本文選題：腦梗死 + 擴散張量成像　； 參考：《中國腦血管病雜志》2015年07期

【摘要】：目的應用磁共振擴散張量成像(DTI)及擴散張量纖維束成像(DTT)評價腦梗死患者皮質脊髓束(CST)損傷程度及與運動功能預后的關系。方法前瞻性納入腦梗死患者68例,行常規(guī)MRI、DWI、DTI檢查,并應用DTT技術進行CST三維重組,于發(fā)病7 d內和3個月時測量腦梗死區(qū)及健側相應區(qū)域白質各向異性分數(shù)(FA),采用Fugl-Meyer量表進行運動功能評分,將CST受累程度分為4級。根據(jù)治療后Fugl-Meyer評分情況將患者分為1組(96~99分,大致恢復正常,16例)、2組(51~95分,部分恢復,34例)、3組(≤50分,恢復差,18例),采用方差分析、Pearson和Spearman相關分析,分析腦梗死區(qū)FA值及CST受累程度與運動功能恢復的關系。結果發(fā)病7 d內和3個月時3組FA的變化幅度[(0.05±0.06、0.08±0.07、0.18±0.02)、(0.11±0.02、0.21±0.06、0.39±0.03)]差異有統(tǒng)計學意義(7 d內F=32.821,3個月時F=192.372,均P0.05)。DTT顯示CST病變側表現(xiàn)為受壓、變形、移位和中斷。發(fā)病7 d內CST等級與患者肢體肌力呈負相關(r=-0.682,P0.01),3個月復查CST等級與患者肢體肌力呈負相關(r=-0.728,P0.01)。結論腦梗死患者梗死區(qū)FA值降低及CST受累程度均與運動功能預后有關。MR DTT能直觀顯示CST受累程度,可為早期判斷腦梗死預后提供重要依據(jù)。
[Abstract]:Objective to evaluate the relationship between the damage degree of the corticospinal tract (CST) and the prognosis of motor function in patients with cerebral infarction by magnetic resonance diffusion tensor imaging (DTI) and diffusion tensor fiber beam imaging (DTT). Methods 68 patients with cerebral infarction were prospectively included, routine MRI, DWI, DTI examination were performed, and DTT technique was used to reconstruct the CST, within 7 d and 3 cases. The white matter anisotropy fraction (FA) in the cerebral infarction area and the corresponding region was measured at month time. The Fugl-Meyer scale was used to score the movement function, and the degree of CST involvement was divided into 4 levels. The patients were divided into 1 groups according to the Fugl-Meyer score after treatment (96~99, roughly normal, 16 cases), and the 2 groups (51~95, partial recovery, 34 cases), and the 3 groups (< < 50 points, poor recovery). 18 cases), using variance analysis, Pearson and Spearman correlation analysis, the relationship between the FA value of cerebral infarction and the degree of CST involvement and the recovery of motor function was analyzed. Results the range of changes of FA in the 3 groups (0.05 + 0.06,0.08 + 0.07,0.18 + 0.02) and (0.11 + 0.02,0.21 + 0.06,0.39 + 0.03) in the 7 d and 3 months was statistically significant (7 d within F=32.821,3). At month F=192.372, P0.05).DTT showed that the CST lesion side showed compression, deformation, displacement and interruption. The CST grade in 7 d was negatively correlated with the patient's limb muscle strength (r=-0.682, P0.01), and the 3 month reexamination CST grade was negatively correlated with the patient's limb muscle strength (r=-0.728, P0.01). .MR DTT can directly display the degree of CST involvement and provide an important basis for early judgement of prognosis of cerebral infarction.

【作者單位】： 河南省商丘市第一人民醫(yī)院神經內科;
【分類號】：R743.3;R445.2

【參考文獻】

相關期刊論文 前2條

1 鄭莎莎;盧潔;李坤成;;擴散張量成像在評價腦梗死預后的研究進展[J];中華老年心腦血管病雜志;2011年10期

2 ;各類腦血管疾病診斷要點[J];中華神經科雜志;1996年06期

【共引文獻】

相關期刊論文 前10條

1 劉劍波,史曉冬;香丹注射液對腦梗死患者血液流變學的干預作用[J];安徽中醫(yī)臨床雜志;2003年04期

2 黃俊臣,周紀平,李彥春;核桃承氣湯對腦梗死急性期輔助治療作用的觀察[J];安徽中醫(yī)臨床雜志;2003年04期

3 龐家善,李樹標,陳艷艷;自擬化痰祛瘀方治療急性腦梗死療效觀察[J];中醫(yī)藥臨床雜志;2004年01期

4 潘啟明,張松林,蘭小平;自擬偏癱方配合早期康復治療腦梗死偏癱56例臨床觀察[J];中醫(yī)藥臨床雜志;2004年02期

5 華卡;復方丹參注射液治療急性腦梗死臨床藥效分析[J];中醫(yī)藥臨床雜志;2004年04期

6 郭漢強;醒腦凈合息風通絡化痰湯對急性腦出血的治療作用[J];中醫(yī)藥臨床雜志;2004年05期

7 張波,鄭軍,鮑遠程,蔡永亮,陳懷珍,王艷昕,王曉e，

本文編號：1830992