基于分段讀出平面回波序列的體素內(nèi)不相干運(yùn)動(dòng)DWI在單純性鼻炎和慢性肥厚性鼻炎中的應(yīng)用
發(fā)布時(shí)間:2018-04-27 08:17
本文選題:磁共振成像 + 體素內(nèi)不相干運(yùn)動(dòng) ; 參考:《中國醫(yī)學(xué)影像技術(shù)》2017年12期
【摘要】:目的研究基于分段讀出平面回波序列(RS-EP)單指數(shù)模型DWI、雙指數(shù)模型體素內(nèi)不相關(guān)運(yùn)動(dòng)(IVIM)成像診斷單純性鼻炎和慢性肥厚性鼻炎的價(jià)值。方法收集鼻阻塞患者20例,按病理結(jié)果分為單純性鼻炎組和慢性肥厚性鼻炎組。所有受試者均接受RS-EP序列的IVIM和單指數(shù)模型DWI檢查,獲得IVIM參數(shù)純擴(kuò)散系數(shù)(D)、假性灌注系數(shù)(D~*)、灌注分?jǐn)?shù)(f)和ADC參數(shù)圖。分別測量2組下鼻甲黏膜的前、中、后部3個(gè)區(qū)域的參數(shù)值。比較2組和3個(gè)區(qū)域間各擴(kuò)散參數(shù)值的差異,采用ROC曲線分析其診斷效能。結(jié)果慢性單純性鼻炎組的ADC和D值分別為(1 938.84±170.46)×10~(-6)mm~2/s和(1 698.91±145.17)×10~(-6)mm~2/s,慢性肥厚性鼻炎組ADC值為(1 681.76±132.21)×10~(-6)mm~2/s,D值為(1 439.39±101.26)×10~(-6)mm~2/s,2組間差異有統(tǒng)計(jì)學(xué)意義(P均0.05)。D~*和f值2組間差異無統(tǒng)計(jì)學(xué)意義(P均0.05)。下鼻甲黏膜前、中、后部ADC值依次增高(P均0.05);下鼻甲前、中、后部D~*值差異無統(tǒng)計(jì)學(xué)意義(P0.05)。ROC曲線分析表明,D值的曲線下面積高于ADC值(0.932±0.044 vs 0.896±0.058,P0.05),其敏感度、特異度、準(zhǔn)確率、陽性預(yù)測值和陰性預(yù)測值分別為92.31%、93.75%、90.00%、93.75%、85.71%。結(jié)論基于RS-EP序列的IVIM成像和單指數(shù)DWI成像在鑒別單純性鼻炎和慢性肥厚性鼻炎中具有較大的應(yīng)用價(jià)值,其中基于IVIM模型的D值較常規(guī)ADC值具有更高的診斷效能。
[Abstract]:Objective to study the diagnostic value of single index model (DWI) based on piecewise readout plane echo sequence (RS-EPV) and single index model (DWI) in diagnosis of simple rhinitis and chronic hypertrophic rhinitis. Methods 20 patients with nasal obstruction were divided into simple rhinitis group and chronic hypertrophic rhinitis group. All subjects were examined by IVIM of RS-EP sequence and single exponential model DWI, and obtained the pure diffusion coefficient of IVIM parameters, pseudo-perfusion coefficient, perfusion fraction) and ADC parameter diagram. The parameters of the anterior, middle and posterior regions of the inferior turbinate mucosa were measured. The difference of diffusion parameters between two groups and three regions was compared, and the diagnostic effectiveness was analyzed by ROC curve. 緇撴灉鎱㈡,
本文編號(hào):1809947
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