本文關鍵詞： 超聲檢查 神經(jīng)內分泌瘤 胰腺腫瘤 時間-強度曲線　出處：《中國醫(yī)學影像技術》2015年01期 　論文類型：期刊論文

【摘要】：目的探討CEUS時間-強度曲線(TIC)定量參數(shù)鑒別胰腺神經(jīng)內分泌腫瘤與胰腺癌的臨床價值。方法回顧獲病理診斷的43例神經(jīng)內分泌腫瘤和胰腺癌的CEUS檢查圖像,并對其動態(tài)圖像進行TIC定量分析,得出峰值強度(IMAX)、到達時間(AT)、達峰時間(TTP)、平均渡越時間(mTT)。結果 16例神經(jīng)內分泌腫瘤與周圍胰腺比較,各項定量參數(shù)差異均無統(tǒng)計學意義(P均0.05),其中12例呈高及等增強型神經(jīng)內分泌腫瘤IMAX與周圍胰腺差異有統(tǒng)計學意義[(146.38±60.35)%vs 100%,P=0.02)]。27例胰腺癌TIC參數(shù)與周圍胰腺比較:胰腺癌IMAX小于周圍胰腺[(59.12±26.17)%vs 100%,P0.01],AT大于周圍胰腺[(14.50±6.83)s vs(11.87±4.51)s,P=0.01],mTT小于周圍胰腺[33.30(26.00~73.70)s vs 45.00(35.00~150.10)s,P=0.11)。神經(jīng)內分泌腫瘤與胰腺癌比較:神經(jīng)內分泌腫瘤IMAX大于胰腺癌,TTP小于胰腺癌,mTT大于胰腺癌(P均0.05)。以IMAX≥97.05%診斷神經(jīng)內分泌腫瘤準確率、敏感度、特異度、陽性預測值、陰性預測值,分別為86.05%(37/43)、75.00%(12/16)、92.60%(25/27)、85.71%(12/14)、86.20%(25/29)。聯(lián)合TTP≤7.70s、mTT≥38.80s診斷指標,可提高神經(jīng)內分泌腫瘤的診斷效率。結論 CEUS定量分析可獲得胰腺神經(jīng)內分泌腫瘤和胰腺癌鑒別診斷的定量化指標,可為兩者鑒別診斷提供更客觀、有力證據(jù)。
[Abstract]:Objective to study the time-intensity curve of CEUS. The clinical value of quantitative parameters in differentiating pancreatic neuroendocrine tumor from pancreatic carcinoma. Methods CEUS images of 43 cases of neuroendocrine tumor and pancreatic carcinoma diagnosed by pathology were reviewed. The TIC quantitative analysis of the dynamic image shows that the peak intensity is higher than that of the IMAX, the arrival time is ATT, and the peak time is TTP). Results the quantitative parameters of 16 patients with neuroendocrine tumors were not significantly different from those of the surrounding pancreas (P < 0.05). The IMAX of 12 cases with high or equal enhancement neuroendocrine tumors was significantly different from that of the surrounding pancreas. [TIC parameters of 27 cases of pancreatic cancer compared with peripheral pancreas: IMAX of pancreatic cancer is smaller than that of peripheral pancreas. [59.12 鹵26.17 + vs 100% P0.01] AT is greater than the surrounding pancreas. [14. 50 鹵6. 83s vs(11.87 鹵4. 51s P0. 01] mTT is smaller than that of the surrounding pancreas. [33.30 / 26.00 / 73.70 / s vs 45.00 / 35.00 / 150.10 / s. Compared with pancreatic carcinoma, the IMAX of neuroendocrine tumor was higher than that of pancreatic carcinoma. The diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive value of IMAX 鈮，

本文編號：1485439