【摘要】：牛病毒性腹瀉病毒(Bovine viral diarrhea virus,BVDV)有兩種基因型:基因1型(BVDV-1)和基因2型(BVDV-2)。以往的流行病學(xué)調(diào)查顯示BVDV-1的分布和流行區(qū)域更加廣泛,但近年來國內(nèi)BVDV-2的發(fā)病率呈持續(xù)升高趨勢。BVDV-2通常會(huì)引起嚴(yán)重的急性感染和出血綜合征,給養(yǎng)牛業(yè)造成巨大損失。本文就BVDV-2特異性檢測方法和基因分型的建立,型特異性BVDV-2毒株的分離與鑒定,BVDV-2優(yōu)勢分離株的全基因組測定與遺傳特性分析及BVDV-1和BVDV-2抗原和抗體檢測平臺(tái)的建立等方面展開簡要綜述。
[Abstract]:There are two genotypes of bovine viral diarrhea virus (Bovine viral diarrhea virus,BVDV): gene type 1 (BVDV-1) and gene type 2 (BVDV-2). Previous epidemiological investigations showed that the distribution and epidemic areas of BVDV-1 were more extensive, but the incidence of BVDV-2 in China was increasing continuously in recent years. BVDV-2 usually causes severe acute infection and hemorrhage syndrome. Cause a great loss to the cattle industry. In this paper, the establishment of BVDV-2 specific detection method and genotyping, isolation and identification of type-specific BVDV-2 strains, The whole genome determination and genetic characteristics analysis of BVDV-2 dominant isolates and the establishment of detection platforms for BVDV-1 and BVDV-2 antigens and antibodies were briefly reviewed.
【作者單位】： 揚(yáng)州大學(xué)獸醫(yī)學(xué)院;江蘇省動(dòng)物重要疫病與人獸共患病防控協(xié)同創(chuàng)新中心;上海市農(nóng)業(yè)科學(xué)院畜牧獸醫(yī)研究所;江蘇農(nóng)牧科技職業(yè)學(xué)院;
【基金】：科技部畜禽重大疫病防控與高效安全養(yǎng)殖綜合技術(shù)研發(fā)重點(diǎn)專項(xiàng)(2016YFD0500900) 江蘇高校優(yōu)勢學(xué)科建設(shè)工程資助項(xiàng)目 重大動(dòng)物疫病防控技術(shù)引進(jìn)(國家農(nóng)業(yè)部948計(jì)劃,2011-G24) 江蘇省屬高校自然科學(xué)重大基礎(chǔ)研究項(xiàng)目(14KJA230001) 江蘇省農(nóng)業(yè)支撐項(xiàng)目(BE2014358) 泰州市農(nóng)業(yè)科技計(jì)劃項(xiàng)目(TZ201421)
【分類號(hào)】：S852.653

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