【摘要】：牛病毒性腹瀉病毒(Bovine viral diarrhea virus,BVDV)有兩種基因型:基因1型(BVDV-1)和基因2型(BVDV-2)。以往的流行病學調查顯示BVDV-1的分布和流行區(qū)域更加廣泛,但近年來國內BVDV-2的發(fā)病率呈持續(xù)升高趨勢。BVDV-2通常會引起嚴重的急性感染和出血綜合征,給養(yǎng)牛業(yè)造成巨大損失。本文就BVDV-2特異性檢測方法和基因分型的建立,型特異性BVDV-2毒株的分離與鑒定,BVDV-2優(yōu)勢分離株的全基因組測定與遺傳特性分析及BVDV-1和BVDV-2抗原和抗體檢測平臺的建立等方面展開簡要綜述。
[Abstract]:There are two genotypes of bovine viral diarrhea virus (Bovine viral diarrhea virus,BVDV): gene type 1 (BVDV-1) and gene type 2 (BVDV-2). Previous epidemiological investigations showed that the distribution and epidemic areas of BVDV-1 were more extensive, but the incidence of BVDV-2 in China was increasing continuously in recent years. BVDV-2 usually causes severe acute infection and hemorrhage syndrome. Cause a great loss to the cattle industry. In this paper, the establishment of BVDV-2 specific detection method and genotyping, isolation and identification of type-specific BVDV-2 strains, The whole genome determination and genetic characteristics analysis of BVDV-2 dominant isolates and the establishment of detection platforms for BVDV-1 and BVDV-2 antigens and antibodies were briefly reviewed.
【作者單位】： 揚州大學獸醫(yī)學院;江蘇省動物重要疫病與人獸共患病防控協(xié)同創(chuàng)新中心;上海市農(nóng)業(yè)科學院畜牧獸醫(yī)研究所;江蘇農(nóng)牧科技職業(yè)學院;
【基金】：科技部畜禽重大疫病防控與高效安全養(yǎng)殖綜合技術研發(fā)重點專項(2016YFD0500900) 江蘇高校優(yōu)勢學科建設工程資助項目 重大動物疫病防控技術引進(國家農(nóng)業(yè)部948計劃,2011-G24) 江蘇省屬高校自然科學重大基礎研究項目(14KJA230001) 江蘇省農(nóng)業(yè)支撐項目(BE2014358) 泰州市農(nóng)業(yè)科技計劃項目(TZ201421)
【分類號】：S852.653

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