動物醉酒實驗?zāi)Ｐ偷难芯?/H1>
發(fā)布時間：2019-01-21 07:05
【摘要】：過量飲酒會給人們帶來諸多傷害,甚至可導(dǎo)致生命和財產(chǎn)的損失,所以既想飲酒又不想醉酒成了許多飲酒者的愿望,這就使解酒產(chǎn)品的前途一片大好。但目前尚無一個系統(tǒng)的研究解酒產(chǎn)品解酒效果的實驗體系及一個檢驗其解酒效果的檢驗標(biāo)準,因而影響了它的研發(fā)與消費。研制開發(fā)解酒產(chǎn)品需要進行大量的實驗研究,尤其是動物醉酒實驗,即需要建立動物醉酒實驗?zāi)Ｐ�。目前未查到國�?nèi)已建立起動物醉酒實驗?zāi)Ｐ偷南嚓P(guān)報道。因此,為了使動物醉酒實驗更科學(xué),重復(fù)性更好,我們的工作就是要建立起實驗用酒劑量與動物醉酒現(xiàn)象關(guān)系的動物醉酒模型,用于對解酒物質(zhì)的評價。 本研究主要是進行動物(小鼠)醉酒實驗和色譜分析實驗。工作分為三部分。 1.按實驗動物學(xué)的要求,選擇適宜的動物。 2.設(shè)計與動物醉酒有關(guān)的實驗(曠場實驗、滾筒實驗等)。 3.通過用動物醉酒模型及氣相色譜對解酒物質(zhì)解酒效果的分析,檢驗?zāi)Ｐ偷目尚行浴?所得動物醉酒實驗?zāi)Ｐ桶?小鼠無影響灌胃劑量;小鼠上頭灌胃劑量;小鼠醉酒灌胃劑量; 小鼠死亡灌胃劑量。
[Abstract]:Excessive drinking will bring a lot of harm to people, and even lead to loss of life and property, so it is the desire of many drinkers to want to drink and not to be drunk, which makes the future of antialcoholism products bright. However, there is no systematic experimental system to study the antialcoholism effect of antialcoholic products and a test standard to test its antialcoholism effect, which has affected its research and development and consumption. Research and development of antialcoholism products need a lot of experimental research, especially animal drunkenness experiment, that is to say, it is necessary to establish animal drunken experimental model. At present, there is no related report that animal drunken experimental model has been established in China. Therefore, in order to make the animal drunken experiment more scientific and reproducible, our work is to establish the animal drunken model which is related to the experimental alcohol dosage and the animal drunkenness phenomenon, which can be used to evaluate the antialcoholism substance. This research mainly carries on the animal (mouse) drunkenness experiment and the chromatographic analysis experiment. The work is divided into three parts. 1. According to the requirements of experimental zoology, select suitable animals. 2. Design experiments related to animal drunkenness (open field experiment, roller experiment, etc.) 3. The feasibility of the model was tested by the analysis of the effect of the animal drunkenness model and gas chromatography on the antialcoholism substance. The experimental model of animal intoxication includes: the dose of mice without effect, the dose of upper head of mice, the dose of intoxication of mice, and the dose of death of mice.
【學(xué)位授予單位】：中國農(nóng)業(yè)大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2005
【分類號】：R-332
【引證文獻】
相關(guān)期刊論文 前2條
1 張夢妍;鄭露;黨好;李春艷;許欣;徐家玉;饒家權(quán);馬斌;杜禮泉;;濃香型白酒醉酒度評價動物模型的建立[J];現(xiàn)代預(yù)防醫(yī)學(xué);2010年19期
2 鄭露;張夢妍;彭彥卿;黨好;齊亞娜;許欣;王晶;饒家權(quán);馬斌;杜禮泉;;不同醉酒度濃香型白酒對小鼠血中乙醇代謝的影響[J];現(xiàn)代預(yù)防醫(yī)學(xué);2010年19期
相關(guān)碩士學(xué)位論文 前1條
1 黃敏;玉米醒酒肽產(chǎn)品研制及其功效研究[D];齊齊哈爾大學(xué);2012年
，
本文編號：2412419
本文鏈接：http://sikaile.net/yixuelunwen/binglixuelunwen/2412419.html
[Abstract]:Excessive drinking will bring a lot of harm to people, and even lead to loss of life and property, so it is the desire of many drinkers to want to drink and not to be drunk, which makes the future of antialcoholism products bright. However, there is no systematic experimental system to study the antialcoholism effect of antialcoholic products and a test standard to test its antialcoholism effect, which has affected its research and development and consumption. Research and development of antialcoholism products need a lot of experimental research, especially animal drunkenness experiment, that is to say, it is necessary to establish animal drunken experimental model. At present, there is no related report that animal drunken experimental model has been established in China. Therefore, in order to make the animal drunken experiment more scientific and reproducible, our work is to establish the animal drunken model which is related to the experimental alcohol dosage and the animal drunkenness phenomenon, which can be used to evaluate the antialcoholism substance. This research mainly carries on the animal (mouse) drunkenness experiment and the chromatographic analysis experiment. The work is divided into three parts. 1. According to the requirements of experimental zoology, select suitable animals. 2. Design experiments related to animal drunkenness (open field experiment, roller experiment, etc.) 3. The feasibility of the model was tested by the analysis of the effect of the animal drunkenness model and gas chromatography on the antialcoholism substance. The experimental model of animal intoxication includes: the dose of mice without effect, the dose of upper head of mice, the dose of intoxication of mice, and the dose of death of mice.
【學(xué)位授予單位】：中國農(nóng)業(yè)大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2005
【分類號】：R-332
【引證文獻】
相關(guān)期刊論文 前2條
1 張夢妍;鄭露;黨好;李春艷;許欣;徐家玉;饒家權(quán);馬斌;杜禮泉;;濃香型白酒醉酒度評價動物模型的建立[J];現(xiàn)代預(yù)防醫(yī)學(xué);2010年19期
2 鄭露;張夢妍;彭彥卿;黨好;齊亞娜;許欣;王晶;饒家權(quán);馬斌;杜禮泉;;不同醉酒度濃香型白酒對小鼠血中乙醇代謝的影響[J];現(xiàn)代預(yù)防醫(yī)學(xué);2010年19期
相關(guān)碩士學(xué)位論文 前1條
1 黃敏;玉米醒酒肽產(chǎn)品研制及其功效研究[D];齊齊哈爾大學(xué);2012年
，本文編號：2412419
本文鏈接：http://sikaile.net/yixuelunwen/binglixuelunwen/2412419.html
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