【摘要】： 睡眠是人體的基本生理和心理的需要,由于各種原因引起的睡眠剝奪可對(duì)人體的各方面功能特別是認(rèn)知功能產(chǎn)生影響,主要包括記憶、注意力及警覺(jué)水平等。研究睡眠剝奪對(duì)認(rèn)知影響的作用機(jī)理不僅是探索睡眠作用機(jī)制的一條有效途徑,而且為提出對(duì)抗措施提供依據(jù)。因此國(guó)外對(duì)該領(lǐng)域的研究通過(guò)腦功能成像、心理科學(xué)評(píng)價(jià)、電生理方法等,已得到一些初步結(jié)論,但尚未形成統(tǒng)一的評(píng)價(jià)方法。國(guó)內(nèi)這方面的研究多側(cè)重于心理學(xué)的評(píng)價(jià)方法。采用電生理的方法來(lái)研究睡眠剝奪對(duì)認(rèn)知功能的影響,所得數(shù)據(jù)是腦神經(jīng)元群活動(dòng)的直接客觀反映。與一般心理學(xué)研究方法不同的是,這種方法不但可以對(duì)外來(lái)刺激下的功能反應(yīng)進(jìn)行研究,還可研究大腦的自發(fā)功能狀態(tài)。本研究采用基于腦電EEG數(shù)據(jù)的電生理方法來(lái)評(píng)價(jià)睡眠剝奪對(duì)認(rèn)知活動(dòng)的影響。 由于人體在認(rèn)知過(guò)程中所直接面對(duì)的常常是關(guān)于感覺(jué)和心理的記憶而不是感覺(jué)和心理本身,即使在沒(méi)有明顯回憶時(shí)也有感覺(jué)記憶和短時(shí)記憶起作用。因此本研究主要關(guān)注的是睡眠剝奪對(duì)記憶特別是短時(shí)記憶所造成的影響。本研究根據(jù)認(rèn)知心理學(xué)中關(guān)于短時(shí)記憶的理論和最新研究成果,通過(guò)應(yīng)用不同的刺激材料,包括視覺(jué)的不同顏色記憶材料與聽(tīng)覺(jué)的不同數(shù)組的記憶材料進(jìn)行的記憶測(cè)試實(shí)驗(yàn),從而從視覺(jué)到聽(tīng)覺(jué)全方位的對(duì)睡眠剝奪造成的損害進(jìn)行了評(píng)定。以往的電生理分析方法主要采用的是事件相關(guān)電位( Event-related Potential ,ERP)成分分析法,只是從單個(gè)腦區(qū)出發(fā)對(duì)心理認(rèn)知功能加以研究。但由于大腦的認(rèn)知過(guò)程是大腦各功能區(qū)共同整合的結(jié)果,因此本研究采用關(guān)注腦區(qū)同步化的評(píng)價(jià)及研究手段,通過(guò)對(duì)腦電EEG數(shù)據(jù)的相關(guān)性分析和腦部FFT成像分析,探討了睡眠剝奪對(duì)短時(shí)記憶影響的作用機(jī)制。 本研究發(fā)現(xiàn)睡眠剝奪主要是造成大腦活動(dòng)減弱區(qū)域的偏移與集中,各功能區(qū)之間的關(guān)聯(lián)下降,發(fā)現(xiàn)睡眠剝奪對(duì)視覺(jué)記憶的損害主要是對(duì)額葉造成了影響,從而降低了記憶的編碼階段的作用及功能;而對(duì)聽(tīng)覺(jué)記憶的損害主要是對(duì)頂葉和顳葉造成影響,從而損害記憶提取階段的作用及功能。
[Abstract]:Sleep is the basic physiological and psychological needs of the human body. Sleep deprivation caused by various reasons can have an impact on all aspects of human body functions, especially cognitive function, including memory, attention and alertness. Studying the mechanism of sleep deprivation on cognition is not only an effective way to explore the mechanism of sleep, but also provides a basis for countermeasures. Therefore, some preliminary conclusions have been obtained through brain functional imaging, psychological science evaluation, electrophysiological methods and so on, but a unified evaluation method has not yet been formed. Domestic research focuses on the evaluation methods of psychology. The effects of sleep deprivation on cognitive function were studied by electrophysiological method. Different from general psychological research methods, this method can not only study the functional responses to external stimuli, but also study the state of spontaneous function of the brain. In this study, electrophysiological methods based on EEG data were used to evaluate the effects of sleep deprivation on cognitive activity. Because the human body in the cognitive process is often directly faced with the feeling and psychological memory rather than the feeling and psychology itself, even when there is no obvious memory, there are sensory memory and short-term memory to play a role. Therefore, this study focuses on the effects of sleep deprivation on memory, especially short-term memory. According to the theory of short-term memory in cognitive psychology and the latest research results, the experiment was carried out by using different stimulative materials, including the memory materials of different colors of vision and different arrays of hearing. The damage caused by sleep deprivation was evaluated from visual to auditory. The previous methods of electrophysiological analysis mainly used event-related potential (Event-related Potential, ERP) component analysis, only from a single brain area to study the psychological cognitive function. However, because the cognitive process of the brain is the result of the integration of the functional regions of the brain, this study adopts the evaluation and research methods of paying close attention to the synchronization of the brain regions, through the correlation analysis of EEG data and the analysis of brain FFT imaging. To explore the effect of sleep deprivation on short-term memory. In this study, we found that sleep deprivation mainly caused the deviation and concentration of reduced brain activity and the decrease of the correlation between the functional areas. It was found that the damage of sleep deprivation to the visual memory was mainly caused by the influence on the frontal lobe. Thus, the function and function of the coding stage of memory are reduced. The impairment of auditory memory mainly affects parietal lobe and temporal lobe, thus impairing the function and function of memory extraction stage.
【學(xué)位授予單位】：天津大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2007
【分類號(hào)】：R363

【引證文獻(xiàn)】

相關(guān)博士學(xué)位論文 前1條

1 吳冠儒;臺(tái)北地區(qū)慢性失眠癥與記憶功能損害相關(guān)性調(diào)查及中藥干預(yù)研究[D];北京中醫(yī)藥大學(xué);2011年

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本文編號(hào)：2368395