神經(jīng)系統(tǒng)通過(guò)電活動(dòng)實(shí)現(xiàn)信息處理及生物功能,電活動(dòng)的節(jié)律和時(shí)空行為是功能的動(dòng)力學(xué)表征.神經(jīng)電生理實(shí)驗(yàn)結(jié)合理論模型,借助于分岔揭示了外界激勵(lì)、參數(shù)和噪聲調(diào)控下的周期、混沌和隨機(jī)等多樣性的節(jié)律模式及其節(jié)律的復(fù)雜轉(zhuǎn)遷規(guī)律,揭示了感覺(jué)神經(jīng)對(duì)信息（如血壓壓力信號(hào)和痛覺(jué)信息）的節(jié)律編碼機(jī)制,揭示了突觸噪聲擴(kuò)大腦神經(jīng)元的信息傳遞能力并對(duì)能力強(qiáng)弱進(jìn)行了分類,結(jié)果可用于提高信息檢測(cè)能力和指導(dǎo)鎮(zhèn)痛;借助于單神經(jīng)元節(jié)律的動(dòng)力學(xué)——如分岔和簇放電節(jié)律的快慢動(dòng)力學(xué)——解釋了網(wǎng)絡(luò)功能異常的時(shí)空行為,如藥物調(diào)控腦皮層的螺旋波/癲癇和慢抑制耦合調(diào)控的運(yùn)動(dòng)網(wǎng)絡(luò)的同步轉(zhuǎn)遷/運(yùn)動(dòng)模式異常,結(jié)果給出了調(diào)控系統(tǒng)功能的途徑;通過(guò)大數(shù)據(jù)分析獲得自閉癥患者的腦功能網(wǎng)絡(luò)的時(shí)空行為特征——癥狀相關(guān)腦區(qū)的同步活動(dòng)降低,給出了用于診斷的潛在指標(biāo).通過(guò)新實(shí)驗(yàn)發(fā)現(xiàn)、新建理論模型、新分析方法和新觀點(diǎn)闡釋,揭示了神經(jīng)系統(tǒng)的復(fù)雜動(dòng)力學(xué),認(rèn)識(shí)和解釋了神經(jīng)系統(tǒng)的信息處理機(jī)制和異常生物功能/疾病,具有重要科學(xué)意義和潛在應(yīng)用價(jià)值. 

【文章來(lái)源】：力學(xué)學(xué)報(bào). 2017,49(02)北大核心EICSCD

【文章頁(yè)數(shù)】：11 頁(yè)

【參考文獻(xiàn)】：
期刊論文
[1]Spatiotemporal dynamics in a network composed of neurons with different excitabilities and excitatory coupling[J]. XIAO Wei Wei,GU Hua Guang,LIU Ming Rui.  Science China（Technological Sciences）. 2016(12)
[2]Potassium-induced bifurcations and chaos of firing patterns observed from biological experiment on a neural pacemaker[J]. GU HuaGuang,CHEN ShengGen.  Science China（Technological Sciences）. 2014(05)
[3]生物神經(jīng)元系統(tǒng)同步轉(zhuǎn)遷動(dòng)力學(xué)問(wèn)題[J]. 王青云,張紅慧.  力學(xué)進(jìn)展. 2013(01)
[4]Parameter Diversity Induced Multiple Spatial Coherence Resonances and Spiral Waves in Neuronal Network with and Without Noise[J]. 李玉葉,賈冰,古華光,安書成.  Communications in Theoretical Physics. 2012(05)
[5]Dynamics of firing patterns,synchronization and resonances in neuronal electrical activities:experiments and analysis[J]. Qishao Lu Huaguang Gu Zhuoqin Yang Xia Shi Lixia Duan Yanhong Zheng School of Science,Beihang University,100191 Beijing,China College of Life Science,Shaanxi Normal University,710062 Xi’ an,China School of Science,Beijing University of Posts and Telecommunications,100876 Beijing,China College of Science,North China University of Technology,100144 Beijing,China School of Mathematics and Computer Science.Fujian Normal University,Fuzhou 350007,China.  Acta Mechanica Sinica. 2008(06)
[6]生物神經(jīng)網(wǎng)絡(luò)系統(tǒng)動(dòng)力學(xué)與功能研究[J]. 陸啟韶,劉深泉,劉鋒,王青云,侯中懷,鄭艷紅.  力學(xué)進(jìn)展. 2008(06)



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