發(fā)布時(shí)間：2018-10-18 09:43

【摘要】：纖維結(jié)締組織在身體中的作用是支撐、連接和分隔不同的組織和器官。最近,人體斷肢解剖研究證實(shí),一種定向纖維結(jié)締組織組成了一種長(zhǎng)程液體傳輸通路。其解剖位置有兩種:皮膚傳輸通路(包括真皮、皮下組織和脂肪小葉間隔)和血管周圍傳輸通路(靜脈和動(dòng)脈周圍纖維結(jié)締組織)。這種纖維通路的三維空間內(nèi)部結(jié)構(gòu)是一種縱向分布、相互連接的纖維絲,在每一根纖維絲及其周圍水凝膠之間形成了一種固液界面區(qū);纖維結(jié)締組織中的液體能夠通過這種界面區(qū)傳輸,命名為"生物界面流體傳輸通路";存在于各種組織和器官纖維基質(zhì)中的液體,很可能并沒有被束縛在"組織凝膠"中,而是在尚未明確的某種物理機(jī)制的作用下,朝向一定的方向傳輸。這些研究結(jié)果為理解纖維結(jié)締組織的功能提供了一個(gè)新的視角。
[Abstract]:The role of fibrous connective tissue in the body is to support, connect, and separate different tissues and organs. Recently, anatomical studies of human amputated limbs have confirmed that a directional fibrous connective tissue forms a long-range liquid transport pathway. There are two anatomical sites: the cutaneous transmission pathway (including dermis, subcutaneous tissue and fat interlobular septum) and the perivascular transmission pathway (vein and periarterial fibrous connective tissue). The three-dimensional internal structure of the fiber pathway is a longitudinal distribution of the interlinked fiber filament, forming a solid-liquid interface between each fiber filament and its surrounding hydrogel. Liquids in fibrous connective tissues can be transported through this interfacial region, known as the "biological interface fluid transport pathway"; liquids found in various tissue and organ fibrous matrices are probably not bound to "tissue gels." Rather, it is transmitted in a certain direction under the action of some undefined physical mechanism. These findings provide a new perspective for understanding the function of fibrous connective tissue.
【作者單位】： 北京醫(yī)院國家老年醫(yī)學(xué)中心;國家納米科學(xué)中心;中國科學(xué)院計(jì)算技術(shù)研究所;
【基金】：“973”項(xiàng)目(2015CB554507) 國家自然科學(xué)基金(31350002)資助課題
【分類號(hào)】：R33

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