本文選題：食物過敏 + 動物模型　； 參考：《現(xiàn)代預(yù)防醫(yī)學(xué)》2017年09期

【摘要】：食品安全問題受到世界各國的關(guān)注,隨著新食物產(chǎn)品的不斷開發(fā)研究,關(guān)于是否會增加人體致敏風(fēng)險等問題成為眾專家學(xué)者競相爭論的焦點,嚙齒類動物模型以其特有的優(yōu)勢在食物致敏性評價中占有重要位置,本文例舉了BN大鼠、Balb/c小鼠、C3H/HeJ小鼠此三類最具代表性的嚙齒類動物模型,并對致敏過程中常見致敏原及其影響因素、致敏途徑和體內(nèi)檢測指標(biāo)作一綜述,為食品致敏性評價提供參考。
[Abstract]:The problem of food safety has attracted the attention of all countries in the world. With the continuous development and research of new food products, the issue of whether it will increase the risk of human sensitization has become the focus of debate among the experts and scholars. The rodent model occupies an important position in the evaluation of food sensitivities with its unique advantages. This article exemplifies the BN rat, Balb/c Mice and C3H/HeJ mice are the three most representative rodent models. The common sensitivities and their influencing factors in the sensitization process, the sensitization pathway and the detection indexes in the body are reviewed to provide a reference for the evaluation of food sensitivities.
【作者單位】： 濟(jì)南大學(xué)山東省醫(yī)學(xué)科學(xué)院醫(yī)學(xué)與生命科學(xué)學(xué)院;山東省醫(yī)學(xué)科學(xué)院山東省職業(yè)衛(wèi)生與職業(yè)病防治研究院;
【基金】：山東省醫(yī)藥衛(wèi)生科技發(fā)展計劃項目(2014WS0332)
【分類號】：R155;R-332

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本文編號：1922243