本文選題：雄激素 + 體脂　； 參考：《中國現(xiàn)代醫(yī)學雜志》2017年22期

【摘要】：目的探討青藏高原地區(qū)雄激素對中年婦女體脂的影響。方法選取2014年6月-2015年5月在青海紅十字醫(yī)院進行體檢的116名健康婦女作為研究對象,根據(jù)月經(jīng)狀態(tài)將所有患者分為生育期(n=31)、絕經(jīng)過渡期(n=26)和絕經(jīng)后期(n=59)。比較3組的年齡、體重指數(shù)(BMI)、體脂指標以及血脫氫表雄酮(DHEA)、性激素結(jié)合球蛋白(SHBG)、總睪酮(TT)及游離雄激素指數(shù)(FAI)等水平。采用Pearson相關(guān)系數(shù)分析體脂指標和雄激素的關(guān)系。結(jié)果生育期婦女的年齡、軀干脂肪占全身脂肪含量的百分比、A/G均低于其他兩組(P0.05),男性區(qū)域的脂肪比例低于絕經(jīng)后期婦女。絕經(jīng)過渡期婦女的年齡、軀干脂肪占全身脂肪含量的百分比低于絕經(jīng)后期婦女,差異有統(tǒng)計學意義(P0.05)。絕經(jīng)后期的TT、FAI均低于其他兩組,差異有統(tǒng)計學意義(P0.05)。Pearson分析結(jié)果表明,TT與BMI、全身脂肪組織的總含量及比例呈正相關(guān)(P0.05),FAI與BMI、全身脂肪組織的總含量及比例、男性區(qū)域的脂肪比例、A/G呈正相關(guān)(P0.05)。結(jié)論青藏高原地區(qū)中年婦女的雄激素水平越高,體脂含量也更多,更趨向于中心性分布,但雄激素可能不是主要影響因素。
[Abstract]:Objective to study the effect of androgen on body fat in middle-aged women in Qinghai-Tibet Plateau. Methods 116 healthy women who underwent physical examination in Qinghai Red Cross Hospital from June 2014 to May 2015 were selected as study subjects. According to menstrual status, all the patients were divided into three groups, I. e. Age, body mass index (BMI), body fat index (BMI), serum dehydroepiandrosterone (DHEAA), sex hormone binding globulin (SHBG), total testosterone (TTT) and free androgen index (FAI) were compared among the three groups. Pearson correlation coefficient was used to analyze the relationship between body fat index and androgen. Results the age and the percentage of trunk fat in whole body fat of women in reproductive period were lower than those of the other two groups (P 0.05), and the percentage of fat in male region was lower than that in postmenopausal women. The percentage of trunk fat in body fat in menopausal transitional women was lower than that in postmenopausal women (P 0.05). In postmenopausal women, the levels of TTU FAI were significantly lower than those of the other two groups. The results of Pearson analysis showed that there was a positive correlation between TT and BMI. the total content and proportion of body adipose tissue were positively correlated with FAI and BMI, and the total content and proportion of adipose tissue. The ratio of fat to fat in the male area was positively correlated with that of P / P 0.05. Conclusion the higher the androgen level and the more body fat content, the more central distribution of androgen, but androgen may not be the main influencing factor in Qinghai-Xizang Plateau.
【作者單位】： 青海紅十字醫(yī)院婦科;
【分類號】：R33

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