大鼠腹膜粘連的模型構建與評價
發(fā)布時間:2018-05-08 16:47
本文選題:腹膜粘連 + 動物模型。 參考:《中國比較醫(yī)學雜志》2017年09期
【摘要】:腹膜粘連是腹部外科手術術后的常見并發(fā)癥,可導致腸梗阻、慢性盆腹腔疼痛、不孕等,并可增加再入院率、再次手術的風險及經(jīng)濟負擔。建立合適的腹膜粘連動物模型對于研究腹膜粘連及其并發(fā)癥的發(fā)病機制、治療和預防等具有重要的作用。粘連模型動物中以大鼠最為常用,根據(jù)腹膜粘連形成的不同因素,其造模的方式也多種多樣,但目前尚無任何一種造模方式及評價方法可代表所有情況。本文對目前大鼠腹膜粘連模型常用的造模方式、評價方法作一綜述。
[Abstract]:Peritoneal adhesion is a common complication after abdominal surgery, which can lead to intestinal obstruction, chronic pelvic and abdominal pain, infertility and so on. It can also increase the readmission rate, the risk and economic burden of reoperation. The establishment of a suitable animal model of peritoneal adhesion plays an important role in studying the pathogenesis, treatment and prevention of peritoneal adhesion and its complications. Rats are the most commonly used adhesions model, according to the different factors of peritoneal adhesion formation, the way of modeling is also varied, but there is no one model and evaluation method can represent all the conditions. In this paper, the methods and evaluation methods of rat peritoneal adhesion model are reviewed.
【作者單位】: 汕頭大學醫(yī)學院第二附屬醫(yī)院;
【分類號】:R-332;R656
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1 茹金泉,周卸來,章志量,倪有娣,江素君,杜紅英,鄭婷;缺血性大鼠腹膜粘連模型的建立及其病理學特征[J];杭州醫(yī)學高等?茖W校學報;2003年03期
2 周海金;章志量;杜紅英;戴一帆;茹金泉;;缺血性大鼠腹膜粘連模型的建立[J];杭州師范學院學報(自然科學版);2005年06期
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