本文選題：生肌玉紅膏 + 深Ⅱ度燒傷��； 參考：《中國衛(wèi)生標(biāo)準(zhǔn)管理》2016年22期

【摘要】：目的探討生肌玉紅膏對深Ⅱ度燒傷模型大鼠創(chuàng)面氧化應(yīng)激水平的影響。方法 96只大鼠被隨機(jī)分為3組(A組、B組、C組),每組32只,A、B組均制成深I(lǐng)I度燒傷動物模型,A組傷后給予生肌玉紅膏換藥,B組給予凡士林換藥,C組為正常對照組,比較3組大鼠燒傷后不同時間點(3 d、7 d、14 d、21 d)創(chuàng)面氧化應(yīng)激水平的變化。結(jié)果與C組比較,A、B組大鼠燒傷后不同時間點創(chuàng)面氧化應(yīng)激水平升高(P0.05);建模后3 d,A,B兩組創(chuàng)面氧化應(yīng)激水平差異無統(tǒng)計學(xué)意義(P0.05);在建模后7,14,21 d,A組燒傷后不同時間點創(chuàng)面氧化應(yīng)激水平與B組差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論深Ⅱ度燒傷后創(chuàng)面氧化應(yīng)激水平升高,不利于創(chuàng)面愈合,生肌玉紅膏對燒傷模型大鼠創(chuàng)面氧化應(yīng)激水平具有明顯抑制作用,從而有助于促進(jìn)創(chuàng)面愈合。
[Abstract]:Objective to investigate the effect of Shengjiyu Hong ointment on oxidative stress of deep second degree burn rats. Methods Ninety-six rats were randomly divided into three groups: group A (n = 32), group B (n = 32), and group A (n = 32). The changes of oxidative stress were compared at different time points after burn in three groups. Results compared with group C, the oxidative stress level of burn wound was increased at different time points after burn in group A, and there was no significant difference in oxidative stress level between group A and group C at 3 days after modeling, and there was no significant difference between group A and group A at different time points after 71421 days after modeling. The level of face oxidative stress was significantly different from that of group B (P 0.05). Conclusion the level of oxidative stress is increased after deep second degree burn, which is not conducive to wound healing. Shengjiyu Hong ointment can obviously inhibit the level of oxidative stress in burn model rats, which is helpful to promote wound healing.
【作者單位】： 甘肅中醫(yī)藥大學(xué)臨床醫(yī)學(xué)院;甘肅中醫(yī)藥大學(xué)附屬醫(yī)院普外科;
【基金】：國家自然科學(xué)基金項目(81260543)
【分類號】：R285.5;R-332

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