本文選題：兔　切入點：距下關(guān)節(jié)　出處：《中國運動醫(yī)學(xué)雜志》2016年02期 　論文類型：期刊論文

【摘要】：目的:利用自體半腱肌腱移植建立距跟骨間韌帶重建的動物模型。方法:將72只新西蘭白兔隨機分為重建組、切斷組和對照組。分別于4周、8周、16周、32周取材,對3個實驗組術(shù)前術(shù)后體重變化,重建韌帶的影像學(xué)、組織學(xué)和生物力學(xué)結(jié)果以及術(shù)后距下關(guān)節(jié)的活動范圍進行評估。結(jié)果:術(shù)后8周以后實驗動物體重變化出現(xiàn)差別,韌帶切斷組較重建組體重多增加0.32 kg(P=0.04);影像學(xué)、組織學(xué)和生物力學(xué)均支持移植韌帶成活,生物力學(xué)研究發(fā)現(xiàn)韌帶牽拉時出現(xiàn)2個張力屈服點;術(shù)后3組距下關(guān)節(jié)冠狀面(P0.05)和水平面(P0.001)活動度差異有統(tǒng)計學(xué)意義。結(jié)論:利用自體半腱肌腱移植重建距跟骨間韌帶可有效恢復(fù)距下關(guān)節(jié)的解剖和功能。移植韌帶經(jīng)過壞死、塑形改建、成熟的過程與骨道形成末端結(jié)構(gòu)愈合。對于研究距下關(guān)節(jié)穩(wěn)定性、韌帶斷裂后關(guān)節(jié)的繼發(fā)性改變、韌帶移植重建的轉(zhuǎn)歸提供了良好的動物模型材料。
[Abstract]:Objective: to establish an animal model of reconstruction of intercalcaneal ligament with semitendinosus tendon autograft. Methods: 72 New Zealand white rabbits were randomly divided into reconstruction group, transection group and control group. The changes of body weight before and after operation, the imaging, histological and biomechanical results of the reconstructed ligaments and the range of movement of the subtalar joint in the three experimental groups were evaluated. Results: after 8 weeks of operation, there were differences in the weight changes of the experimental animals. The weight of ligamentotomy group was 0.32 kg / kg, and the survival of graft ligament was supported by imaging, histology and biomechanics. The biomechanical study showed that there were two tension yield points in ligamentum ligamentum. There were statistically significant differences in the range of motion between the three groups (P 0.05) and P 0.001). Conclusion: reconstruction of the intercalcaneal ligament with autogenous semitendinosus tendon can effectively restore the anatomy and function of the subtalar joint. It provides a good animal model material for studying the stability of subtalar joint, the secondary change of joint after ligament rupture and the outcome of ligament graft reconstruction.
【作者單位】： 北京大學(xué)國際醫(yī)院骨科部;北京大學(xué)第三醫(yī)院運動醫(yī)學(xué)研究所;
【分類號】：R687.2;R-332

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本文編號：1620565