甘露糖結(jié)合凝集素相關(guān)絲氨酸蛋白酶與相關(guān)疾病最新研究進(jìn)展
發(fā)布時(shí)間:2018-03-02 12:00
本文選題:甘露糖結(jié)合凝集素 切入點(diǎn):甘露糖結(jié)合凝集素相關(guān)絲氨酸蛋白酶 出處:《中國(guó)老年學(xué)雜志》2017年16期 論文類型:期刊論文
【摘要】:正惡性腫瘤與自身免疫性疾病的發(fā)病率逐年增高,國(guó)內(nèi)外學(xué)者的目光逐漸聚焦在天然免疫這一方面。補(bǔ)體系統(tǒng)則是天然免疫中的關(guān)鍵環(huán)節(jié),其在疾病發(fā)生、發(fā)展過(guò)程中所起作用也越來(lái)越受到重視。補(bǔ)體是存在于人或動(dòng)物血清中一組不耐熱的且具有酶活性的蛋白質(zhì),并非單一分子,是由30多種蛋白成分組成的限制性蛋白酶解系統(tǒng),又稱為補(bǔ)體系統(tǒng)。廣泛參與機(jī)體的多種免疫效應(yīng)機(jī)制。補(bǔ)體需要被激活才能發(fā)揮其相應(yīng)的生物學(xué)作用。激活過(guò)程根據(jù)起始順序的不同分為經(jīng)典途徑、甘露
[Abstract]:The incidence of positive malignant tumors and autoimmune diseases is increasing year by year. The attention of scholars at home and abroad is gradually focused on innate immunity. Complement system is the key link in innate immunity, and it occurs in diseases. The role of complement in human or animal serum is not a single molecule, but is a restriction proteolysis system composed of more than 30 proteins. It is also called complement system. It participates in many kinds of immune effect mechanism. Complement needs to be activated in order to play its corresponding biological function. Activation process is divided into classical way according to different starting sequence, mannose
【作者單位】: 河北北方學(xué)院;
【基金】:河北省高等學(xué)?茖W(xué)技術(shù)研究項(xiàng)目(No.ZC2016015)
【分類號(hào)】:R363
【相似文獻(xiàn)】
相關(guān)期刊論文 前1條
1 趙修竹;補(bǔ)體系統(tǒng)的有限蛋白解[J];上海免疫學(xué)雜志;1997年04期
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