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隱孢子蟲實驗室安全風險評估模型的建立

發(fā)布時間:2018-01-22 04:54

  本文關(guān)鍵詞: 隱孢子蟲 實驗室安全 模糊層次分析法 多指標綜合評分法 出處:《中國血吸蟲病防治雜志》2016年06期  論文類型:期刊論文


【摘要】:目的建立隱孢子蟲實驗室安全風險評估模型,為從事隱孢子蟲相關(guān)操作的實驗室人員做好安全工作和預防實驗室內(nèi)發(fā)生隱孢子蟲感染提供依據(jù)。方法通過查閱文獻和德爾菲法確定隱孢子蟲實驗室感染發(fā)生的風險因素,然后通過模糊層次分析法確定風險因素的權(quán)重,建立隱孢子蟲實驗室安全風險評估模型。結(jié)果建立了隱孢子蟲實驗室安全風險評估模型,各風險指標中糞便樣本處理發(fā)生隱孢子蟲實驗室感染的概率較高,且危害程度高,其發(fā)生可能性、危害程度的指標組合權(quán)重分別為0.111和0.107,屬于高危風險因素。結(jié)論本研究建立的隱孢子蟲實驗室安全風險評估模型具有可行性,可望為實驗室人員做好相應防護措施、預防實驗室內(nèi)發(fā)生隱孢子蟲感染發(fā)生提供依據(jù)。
[Abstract]:Objective to establish a laboratory safety risk assessment model for Cryptosporidium. To provide a basis for the safety work and prevention of Cryptosporidium infection among laboratory personnel engaged in cryptosporidium related operations. Methods the incidence of Cryptosporidium infection in laboratory was determined by literature review and Delphi method. Risk factors. Then the weight of risk factors is determined by fuzzy analytic hierarchy process (AHP) and the model of laboratory safety risk assessment of Cryptosporidium is established. Results the model of laboratory safety risk assessment of Cryptosporidium is established. Among the risk indicators, the probability of laboratory infection of Cryptosporidium in fecal sample treatment was higher, and the degree of harm was high. The probability of occurrence and the combined weight of the index of hazard degree were 0.111 and 0.107, respectively. Conclusion the model of laboratory safety risk assessment of Cryptosporidium is feasible, and it is expected to be a good protective measure for laboratory personnel. To prevent Cryptosporidium infection in laboratory.
【作者單位】: 中國疾病預防控制中心寄生蟲病預防控制所、世界衛(wèi)生組織熱帶病合作中心、衛(wèi)生部寄生蟲病原與媒介生物學重點實驗室;上海市嘉定區(qū)疾病預防控制中心;
【基金】:上海市衛(wèi)生和計劃生育委員會委級課題(20134430)
【分類號】:R382.3
【正文快照】: 隱孢子蟲病是一種以腹瀉為主要臨床表現(xiàn)的人獸共患原蟲病[1]。作為隱孢子蟲病的病原,隱孢子蟲主要寄生于人或其他動物腸上皮細胞的刷狀緣層,亦可寄生于呼吸道、肺、扁桃體、胰腺、膽囊和膽管等器官[1]。隱孢子蟲的感染階段為卵囊,其呈圓形或橢圓形,直徑4~6 mm,并隨宿主糞便或

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