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363例慢性前列腺炎與勃起功能障礙的相關(guān)性研究

發(fā)布時(shí)間:2019-02-15 04:01
【摘要】:目的:通過對(duì)363例慢性前列腺炎(CP)患者的中醫(yī)證型以及合并勃起功能障礙(ED)的情況,探索慢性前列腺炎在中醫(yī)證型上與勃起功能障礙之間的相關(guān)研究,為慢性前列腺炎的辨證論治提供臨床指導(dǎo)意義。方法:將在2015年10月一2017年2月門診就診的363例CP患者,通過國(guó)際前列腺炎癥狀評(píng)分表(NIH-CPSI);國(guó)際前列腺癥狀評(píng)分(IPSS):下尿路癥狀評(píng)價(jià);國(guó)際勃起功能簡(jiǎn)化量表(IIEF-5)及慢性前列腺炎中醫(yī)證型量表調(diào)查慢性前列腺炎患者NIH-CPSI評(píng)分、IPSS評(píng)分、勃起功能障礙及中醫(yī)證型情況,分析慢性前列腺炎患者中醫(yī)證型與勃起功能障礙之間的相關(guān)性。結(jié)果:(1)CP患者總體中醫(yī)證型以復(fù)合證型為主,復(fù)合證型301例,約占82.92%,并且復(fù)合證型中又以濕熱下注型合并氣滯血瘀型多見,182例,占50.14%。單一證型62例,約占17.08%。(2)363例慢性前列腺炎患者前列腺炎癥狀的嚴(yán)重程度(NIH-CPSI評(píng)分)與勃起功能障礙的嚴(yán)重程度(IIEF-5評(píng)分)比較P0.05,有統(tǒng)計(jì)學(xué)意義。慢性前列腺炎患者ED的患病率隨著前列腺炎下尿路癥狀的嚴(yán)重程度而有逐漸升高的趨勢(shì)。說明慢性前列腺炎下尿路癥狀的嚴(yán)重程度可能與ED的患病有一定關(guān)系。(3)182例濕熱下注合并氣滯血瘀型患者合并勃起功能障礙者有79例;119例其他復(fù)合證型患者合并勃起功能障礙者有35例;62例單一證型患者合并勃起功能障礙有24例。根據(jù)所分3種不同證型合并ED的發(fā)生情況,經(jīng)比較χ2=6.435,P=0.05,差異有統(tǒng)計(jì)學(xué)意義。按照IIEF-5評(píng)分將慢性前列腺炎伴有勃起功能障礙患者分為輕度及中重度ED進(jìn)行比較經(jīng)比較χ2 =6.435,P=0.04差異有統(tǒng)計(jì)學(xué)意義。3種證型中NIH-CPSI評(píng)分與IIEF-5評(píng)分之間呈負(fù)相關(guān)(濕熱下注合并氣滯血瘀型:r=-0.429,P0.001,其他復(fù)合證型:r=-0.406,P0.001,單一證型:r=-0.458,P0.001,總體:r=-0.422,P0.001)。IPSS評(píng)分和IIEF-5評(píng)分之間呈負(fù)相關(guān)(濕熱下注合并氣滯血瘀型:r=-0.171,PO.001,其他復(fù)合證型:r=-0.307,P0.001,單一證型:r=-0.446,P0.001,總體:r=-0.279,P0.001)。結(jié)論:本次調(diào)查,濕熱下注合并氣滯血瘀型是CP患者的主要的中醫(yī)證型。慢性前列腺炎在癥狀的嚴(yán)重程度上與ED有相關(guān)性。CP患者,其下尿路癥狀的嚴(yán)重程度與ED的發(fā)生具有相關(guān)性。CP患者中醫(yī)證型與ED的發(fā)生有一定相關(guān)性,可能是ED誘發(fā)因素,也有可能是其病機(jī)基礎(chǔ)。
[Abstract]:Objective: to investigate the relationship between chronic prostatitis and erectile dysfunction (ED) in patients with chronic prostatitis (CP). To provide clinical guidance for the treatment of chronic prostatitis based on syndrome differentiation. Methods: a total of 363 patients with CP from October to February 2017 were enrolled in this study through the International Prostatitis symptom scale (NIH-CPSI), the International Prostate symptom scale (IPSS):) and the urinary tract symptom Assessment (IPSS):). International simplified erectile function scale (IIEF-5) and TCM Syndrome scale for chronic Prostatitis NIH-CPSI score, IPSS score, erectile dysfunction and TCM Syndromes in patients with chronic Prostatitis were investigated. To analyze the correlation between TCM syndromes and erectile dysfunction in patients with chronic prostatitis. Results: (1) the main types of TCM syndromes in patients with CP were compound syndrome type, 301 cases (82.922), and the type of damp-heat injection combined with Qi stagnation and blood stasis was more common in the complex syndrome type, 182 cases (50.14%). (2) the severity of prostatitis symptoms (NIH-CPSI score) in 363 patients with chronic prostatitis was significantly higher than that in erectile dysfunction (IIEF-5 score) (P 0.05). The prevalence of ED in patients with chronic prostatitis tends to increase with the severity of lower urinary tract symptoms of prostatitis. It is suggested that the severity of lower urinary tract symptoms of chronic prostatitis may be related to the prevalence of ED. (3) there were 79 cases with erectile dysfunction in 182 patients with dampness and heat betting combined with Qi stagnation and blood stasis. There were 35 patients with erectile dysfunction and 24 patients with erectile dysfunction in 62 patients with single syndrome. According to the occurrence of ED in three different syndromes, the difference was statistically significant. According to the IIEF-5 score, the patients with chronic prostatitis with erectile dysfunction were divided into mild and moderate to severe ED. There was a negative correlation between the NIH-CPSI score and the IIEF-5 score in the three syndromes (Wet and Heat betting combined with Qi stagnation and Blood stasis: rhi-0.429, P0.001, other syndrome types: rhi-0.406, P0.001, P 0.001, P 0.001). Single syndrome type: r-0.458U P0.001. overall: r-0.422P0.001). IPSS score and IIEF-5 score were negatively correlated (damp-heat betting combined with Qi stagnation and blood stasis type: rhi-0.171 P0.001, P 0.001, P 0.001). Other complex syndromes were r-0.307 (P0.001), single type: r-0.446N P0.001, total: r-0.279 (P0.001). Conclusion: in this investigation, damp-heat betting combined with Qi stagnation and blood stasis is the main TCM syndrome of CP patients. The severity of chronic prostatitis is related to ED. In CP patients, the severity of lower urinary tract symptoms is correlated with the occurrence of ED. There is a certain correlation between TCM syndromes of CP patients and the occurrence of ED, which may be the inducing factor of ED. It may also be the basis of its pathogenesis.
【學(xué)位授予單位】:新疆醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R277.5

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