膽汁反流性胃炎的證素分布特點(diǎn)及相關(guān)因素研究
發(fā)布時(shí)間:2018-05-10 06:53
本文選題:膽汁反流性胃炎 + 證素 ; 參考:《南京中醫(yī)藥大學(xué)》2017年碩士論文
【摘要】:目的:參考證素辨證體系,通過對(duì)膽汁反流性胃炎患者臨床資料分析,初步探究其證素分布規(guī)律及相關(guān)因素,完善本病中醫(yī)辨證體系,指導(dǎo)臨床干預(yù)及治療。方法:收集191例膽汁反流性胃炎患者的病例資料,根據(jù)問卷調(diào)查表搜集的相關(guān)信息,參考朱文鋒教授編寫的《證素辨證學(xué)》中"癥候辨證量表"提取相關(guān)證素,建立數(shù)據(jù)庫,運(yùn)用統(tǒng)計(jì)學(xué)方法,總結(jié)膽汁反流性胃炎的證素分布特點(diǎn)并分析其與多種因素的相關(guān)性。結(jié)果:本次研究人群發(fā)病年齡以51-70歲最多,女性患者多于男性患者,以職員和工人較多。飲酒和辛辣飲食為可能的危險(xiǎn)因素。膽汁反流性胃炎的鏡下反流程度以Ⅰ級(jí)為主。Hp感染率在本病中占14.14%。人群的病理組織學(xué)檢查可見較高程度腺體萎縮及腸化,檢出陽性率為25.13%和21.99%;患者主要的病位證素有胃、肝、脾、膽、大腸,其中胃所占比例最高為76.71%;肝次之,為56.85%;脾、膽及大腸所占比例依次為25.34%、10.96%、6.16%。病位證素組合以雙病位最多(59.59%),其次是單病位(33.56%),其他病位組合少見(6.85%)。病位證素組合以肝胃最多,胃及脾胃次之。主要的病性證素有氣滯(36.99%)、熱(28.77%)、氣虛(26.03%)、血瘀(21.92%)、陰虛(19.86%)、食積(13.70%)、濕(8.22%)、陽虛(4.79%)、寒(3.42%)。雙病性組合較多,單病性次之。實(shí)證為93例(63.70%),虛證22例(15.07%),虛實(shí)夾雜證31例(21.23%)。不同性別的膽汁反流性胃炎患者病位證素分布有差異性。本病的病性證素分布與病理相關(guān)。其證素分布與年齡、Hp感染、鏡下反流程度無相關(guān)性。結(jié)論:本次研究中膽汁反流性胃炎患者女性多于男性,以51-70歲為高發(fā)年齡段。Hp陽性率為14.14%。鏡下反流程度以Ⅰ級(jí)為主。病位證素主要有胃、肝、脾、膽、大腸,病位組合以肝胃為主。其病性證素有氣滯、熱、氣虛、血瘀、陰虛、食積、濕、陽虛、寒;實(shí)證以氣滯和熱最多,虛癥以氣虛、陰虛為主。病性組合以雙病性最多。實(shí)證較虛癥和虛實(shí)夾雜證最多。不同性別的膽汁反流性胃炎患者病位證素分布有差異性。本病的病性證素分布與病理相關(guān)。膽汁反流性胃炎的證素分布與年齡、Hp感染、鏡下反流程度無相關(guān)性。
[Abstract]:Objective: to analyze the clinical data of patients with bile reflux gastritis with reference to syndrome differentiation system, and to explore the distribution of syndromes and related factors, improve the syndrome differentiation system of TCM, and guide clinical intervention and treatment. Methods: the data of 191 patients with bile reflux gastritis were collected. According to the relevant information collected from the questionnaire, the syndrome differentiation scale compiled by Professor Zhu Wenfeng was used to extract the relevant syndromes and to establish a database. The distribution of syndromes in bile reflux gastritis was summarized by statistical method and its correlation with many factors was analyzed. Results: the age of onset in this study was 51-70 years old, female patients were more than male patients, staff and workers were more. Alcohol consumption and spicy diet are possible risk factors. The degree of reflux in bile reflux gastritis was mainly grade 鈪,
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