發(fā)布時間：2018-01-05 03:15

  本文關(guān)鍵詞：活血散瘀湯聯(lián)合圍刺治療尋常型斑塊狀銀屑病的臨床觀察　出處：《黑龍江中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 圍刺 活血散瘀湯 斑塊狀銀屑病 血瘀證

【摘要】：目的:以中醫(yī)學(xué)理論為依據(jù),觀察"活血散瘀湯"聯(lián)合圍刺療法治療尋常型斑塊狀銀屑病(血瘀證)的臨床療效,以皮損面積及嚴(yán)重程度指數(shù)(PASI)評分和中醫(yī)瘙癢癥候評分作為評價指標(biāo),進(jìn)行觀察和分析。方法:將符合入選標(biāo)準(zhǔn)的90名斑塊狀銀屑病患者采用隨機(jī)分組的方法分為治療組、對照組,每組各45人。觀察過程中脫落4例,實(shí)際為治療組42例、對照組44例。治療組給予口服"活血散瘀湯"配合圍刺療法及對照組給予口服"血府逐瘀膠囊",兩組均聯(lián)合外用"凡士林",共治療56天。通過觀察皮損面積及嚴(yán)重程度指數(shù)(PASI)評分變化及瘙癢癥候程度,分別于治療后第28天、第56天記錄評分并進(jìn)行療效判定,以此評價"活血散瘀湯"聯(lián)合圍刺療法的臨床療效。并對患者在治療期間出現(xiàn)的不良反應(yīng)進(jìn)行評估,從而對藥物的安全性進(jìn)行評價。結(jié)果:1.治療第28天,兩組各自于治療前、后相比較,PASI評分和中醫(yī)瘙癢癥候評分均存在顯著性差異(P0.05);治療第56天末,兩組間比較,上述兩指標(biāo)評分均存在顯著性差異(P0.05)。2.治療第56天,以PASI評分的改善程度作為療效評判指數(shù),治療組42例患者中臨床痊愈1例、顯效24例、有效11例、無效6例,總有效率85.71%;相比治療組,對照組44例患者中臨床痊愈0例、顯效1 6例、有效1 7例、無效11例,總有效率75.00%。兩組療效比較存在顯著性差異(P0.05)。結(jié)論:1."活血散瘀湯"聯(lián)合圍刺療法與"血府逐瘀膠囊"聯(lián)合"凡士林"相比,前者在減少銀屑病患者PASI分值及緩解主觀中醫(yī)瘙癢癥候上優(yōu)于后者,療效確切,且安全性高。2."活血散瘀湯"聯(lián)合圍刺是治療尋常型斑塊狀銀屑病血瘀證的有效方法。
[Abstract]:Objective: to observe the clinical effect of "Huoxue Sanyu decoction" combined with peri-acupuncture therapy on plaque psoriasis vulgaris (blood stasis syndrome) based on the theory of traditional Chinese medicine. The index of lesion area and severity (PASI) and the score of pruritus in traditional Chinese medicine (TCM) were used as the evaluation index. Methods: 90 patients with plaque psoriasis were randomly divided into treatment group (n = 45), control group (n = 45) and control group (n = 45). 42 cases in the treatment group and 44 cases in the control group. The treatment group was treated with "Huoxue Sanyu decoction" and the control group was given "Xuefu Zhuyu capsule", both of which were combined with "vaseline". Total 56 days of treatment. By observing the lesion area and severity index (PASI) and the degree of pruritus symptoms, the scores were recorded on the 28th day and the 56th day after the treatment and the curative effect was evaluated. In order to evaluate the clinical efficacy of "Huoxue Sanyu Tang" combined with peri-acupuncture therapy, and to evaluate the adverse reactions of patients during treatment, the safety of the drug was evaluated. Results: 1. The 28th day of treatment. Before and after treatment, there were significant differences between the two groups in PASI score and TCM pruritus score. At the end of the 56th day of treatment, there was significant difference between the two groups in the scores of the above two indexes. On the 56th day of treatment, the improvement degree of the PASI score was taken as the evaluation index of the curative effect. In the treatment group, 1 case was clinically cured, 24 cases were markedly effective, 11 cases were effective, 6 cases were ineffective. The total effective rate was 85.71%. Compared with the treatment group, there were 0 cases of clinical cure, 16 cases of remarkable effect, 17 cases of effective and 11 cases of ineffectiveness in the control group (44 cases). The total effective rate was 75.00. There was a significant difference between the two groups. Conclusion: 1. "Huoxue Sanyu Tang" and "Xuefu Zhuyu capsule" combined with "vaseline" were compared. The former is better than the latter in reducing PASI score and relieving subjective pruritus in psoriasis patients. The combination of Huoxue Sanyu decoction and Peripheral needling is an effective method for the treatment of blood stasis syndrome of plaque psoriasis vulgaris.
【學(xué)位授予單位】：黑龍江中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R275.9

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 胡素娟;黃友光;賀延敏;毛立國;崔勇;;尋常性銀屑病發(fā)病誘因分析[J];中國皮膚性病學(xué)雜志;2016年12期

2 李峰;晉紅中;別志欣;唐國棟;;銀屑病血脂特點(diǎn)分析[J];中國麻風(fēng)皮膚病雜志;2016年07期

3 曹玉婷;孫立;;銀屑病易患基因研究進(jìn)展[J];醫(yī)學(xué)綜述;2016年07期

4 董霞;陳敬;;銀屑病生物治療與光療研究進(jìn)展[J];繼續(xù)醫(yī)學(xué)教育;2016年02期

5 高麗娜;崔元璐;延闊;邱超;;丹參紅花配伍研究進(jìn)展[J];中草藥;2016年04期

6 郭艷明;梁永瑛;顧鈞青;周帥亮;李德華;岑玨;;電針圍刺治療早中期膝骨關(guān)節(jié)炎[J];吉林中醫(yī)藥;2016年01期

7 許筱凰;李婷;王一濤;陸金健;;桃仁的研究進(jìn)展[J];中草藥;2015年17期

8 介思;武偉;杜位良;魏江山;;針刺背俞穴合局部圍刺治療尋常型銀屑病40例臨床觀察[J];中國民族民間醫(yī)藥;2015年16期

9 王曉寧;鄭偉娟;周映;包軍;李家璜;陳東琛;華子春;;銀屑病發(fā)病機(jī)制和治療方法的研究進(jìn)展[J];藥物生物技術(shù);2015年03期

10 姜春燕;王莒生;李元文;周冬梅;張廣中;;養(yǎng)血化斑湯治療斑塊型銀屑病血燥證[J];中國實(shí)驗(yàn)方劑學(xué)雜志;2015年11期

，

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