本文選題：成癮記憶 + 相關(guān)線索反應(yīng)�。� 參考：《心理科學(xué)進(jìn)展》2017年07期

【摘要】：成癮記憶消退致力于消除成癮者相關(guān)線索與藥物獎賞效應(yīng)的聯(lián)結(jié),以達(dá)到消除心理渴求、戒斷成癮行為的目的,但其效果還十分有限。最近,大量的動物和人類實(shí)驗(yàn)研究發(fā)現(xiàn):在相關(guān)線索下,成癮者的激活腦區(qū)不僅包括中腦邊緣皮層-背內(nèi)側(cè)紋狀體,還延伸到感覺運(yùn)動腦區(qū)-背外側(cè)紋狀體。這意味著成癮記憶中存在相關(guān)線索與自動化(習(xí)慣性)用藥行為的聯(lián)結(jié)。所以,與成癮相關(guān)的記憶可能包含兩種不同的成分:一是與藥物獎賞效應(yīng)相關(guān)的情緒記憶,另一種是與用藥動作、技能有關(guān)的動作記憶(程序記憶)。由于在成癮階段,藥物獎賞效應(yīng)對藥物使用和復(fù)發(fā)的作用已經(jīng)相對減少,因此,針對成癮記憶的消退訓(xùn)練,以相關(guān)線索與自動化用藥行為的聯(lián)結(jié)為標(biāo)靶,可能可以取得更好的效果,值得做進(jìn)一步的深入探索。
[Abstract]:Addictive memory regression aims to eliminate the association between addict clues and drug reward effect in order to eliminate psychological craving and abstinence from addictive behavior, but its effect is still very limited. Recently, a large number of animal and human experimental studies have found that the activated brain regions of addicts include not only the marginal cortex-dorsomedial striatum, but also the sensorimotor brain region and the dorsolateral striatum. This means that there is a link in addictive memory to automated (habitual) drug use. Therefore, addiction-related memory may contain two different components: one is emotional memory associated with drug reward effect, and the other is motor memory (programmed memory) related to drug use and skill. Since the effect of drug reward effect on drug use and relapse has been relatively reduced during the addiction phase, the regression training of addictive memory is targeted at the association of relevant clues and automated drug use behaviors. May be able to achieve better results, worthy of further in-depth exploration.
【作者單位】： 廣州大學(xué)心理系廣州大學(xué)心理與腦科學(xué)研究中心;
【基金】：廣東省“創(chuàng)新強(qiáng)校工程”省級重大項(xiàng)目(2014WZDXM02) 國家自然科學(xué)基金(31271113)資助
【分類號】：B845.4
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本文編號：2050406