本文選題：兒童 + 口腔頜面部間隙感染　； 參考：《中華醫(yī)院感染學(xué)雜志》2017年19期

【摘要】：目的分析兒童口腔頜面部間隙感染的臨床特征、病原菌分布及耐藥性,為臨床感染預(yù)防和控制工作提供依據(jù)。方法選取2015年6月-2016年12月的兒童口腔頜面部間隙感染患兒100例,對(duì)所有患兒感染部位、感染來源等臨床特征進(jìn)行觀察和分析,對(duì)膿液標(biāo)本中的病原菌分布及耐藥性進(jìn)行檢測(cè)和比較。結(jié)果患兒感染部位以咀嚼肌間隙、頰間隙、舌下間隙為主,分別占31.00%、24.00%和14.00%,感染來源以腺源性感染為主,占73.00%;分離出143株病原菌,其中,革蘭陽性菌76株占53.15%,革蘭陰性菌62株占43.36%,真菌占5株占3.50%,金黃色葡萄球菌、普雷沃菌、表皮葡萄球菌為主要病原菌;金黃色葡萄球菌、表皮葡萄球菌、肺炎鏈球菌對(duì)青霉素等的耐藥率較高,對(duì)亞胺培南等的耐藥率較低,普雷沃菌、擬桿菌、梭桿菌對(duì)氯霉素等的耐藥率較高,對(duì)甲硝唑、亞胺培南等的耐藥率較低。結(jié)論兒童口腔頜面部間隙感染部位、感染來源、病原菌分布及耐藥性均具有一定的特征性,臨床醫(yī)務(wù)人員應(yīng)對(duì)其給予高度的重視和有效的治療,選取敏感抗菌藥物進(jìn)行抗感染治療,以提高救治成功率,改善患兒預(yù)后。
[Abstract]:Objective to analyze the clinical characteristics, distribution and drug resistance of oral and maxillofacial space infection in children, and to provide evidence for prevention and control of clinical infection. Methods from June 2015 to December 2016, 100 children with oral and maxillofacial space infection were selected. The distribution and drug resistance of pathogenic bacteria in pus samples were detected and compared. Results the sites of infection were masticatory muscle space, buccal space and sublingual space, accounting for 31.00% and 14.00%, respectively. The main source of infection was adenogenic infection (73.00%), 143 strains of pathogenic bacteria were isolated. 76 Gram-positive bacteria accounted for 53.15, 62 Gram-negative bacteria accounted for 43.36, 5 fungi accounted for 3.50. Staphylococcus aureus, Prevoa, Staphylococcus epidermidis were the main pathogens; Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae showed high resistance to penicillin and low resistance to imipenem. The resistance rates of Prevobacter, Bacteroides and Clostridium to chloramphenicol were higher, and those to metronidazole and imipenem were lower. Conclusion the infection site of oral and maxillofacial space in children, the source of infection, the distribution of pathogenic bacteria and drug resistance have some characteristics, which should be paid more attention and effective treatment by clinical medical staff. Select sensitive antimicrobial agents for anti-infection therapy to improve the success rate of treatment and improve the prognosis of children.
【作者單位】： 海口市婦幼保健院口腔科;�？谑械谌嗣襻t(yī)院耳鼻喉科;海南醫(yī)學(xué)院第二附屬醫(yī)院放療科;海南省血液中心;
【基金】：海南省衛(wèi)生廳基金資助項(xiàng)目(瓊衛(wèi)2013-LX-56)
【分類號(hào)】：R446.5;R782.3

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