本文選題：超聲心動描記術(shù) + 先兆子癇��； 參考：《中國醫(yī)學影像技術(shù)》2017年03期

【摘要】：目的采用三維斑點追蹤成像(3D-STI)技術(shù)檢測子癇前期患者左心室收縮功能。方法納入輕度子癇前期患者73例(輕度組)、重度子癇前期患者64例(重度組)和年齡、孕周匹配的健康孕婦60例(對照組)。檢測生化指標和常規(guī)超聲參數(shù),并運用3D-STI測量左心室收縮期整體縱向峰值應(yīng)變(GLS)、整體徑向峰值應(yīng)變(GRS)、整體環(huán)向峰值應(yīng)變(GCS)和整體面積峰值應(yīng)變(GAS),計算面積應(yīng)變不同步指數(shù)(ASDI)。并分析三維應(yīng)變參數(shù)與生化指標及超聲參數(shù)的相關(guān)性。結(jié)果與對照組比較,重度組左心房前后徑(LAD)增大,二尖瓣口舒張期流速比值(E/A)減低,Tei指數(shù)在對照組、輕度組、重度組依次增高(P均0.05)。與對照組比較,輕度組|GLS|、|GAS|降低,ASDI增高,重度組|GLS|、|GRS|、|GCS|、|GAS|和ASDI差異均有統(tǒng)計學意義(P均0.05)。與輕度組比較,重度組GLS、GAS明顯降低,ASDI明顯增高(P均0.05)。|GLS|與Tei指數(shù)呈負相關(guān)(r=-0.471,P=0.036);|GAS|與LVEF呈正相關(guān)(r=0.051,P=0.028),與Tei指數(shù)呈負相關(guān)(r=-0.612,P=0.017);ASDI與心臟脂肪酸結(jié)合蛋白(H-FABP)呈負相關(guān)(r=-0.525,P=0.046),與Tei指數(shù)呈正相關(guān)(r=0.489,P=0.037)。結(jié)論子癇前期患者左心室收縮功能明顯受損,心肌應(yīng)變能力下降,3D-STI技術(shù)可早期無創(chuàng)評價子癇前期患者左心室收縮功能變化。
[Abstract]:Objective to detect left ventricular systolic function in patients with preeclampsia by three-dimensional dot-tracking imaging (3D-STI). Methods 73 patients with mild preeclampsia (mild group), 64 patients with severe preeclampsia (severe group) and 60 healthy pregnant women with age and gestational week matched (control group) were included. Biochemical parameters and conventional ultrasound parameters were measured. The global longitudinal peak strain (GLSN), global radial peak strain (GRSs), global circumferential peak strain (GCSs) and global area peak strain (GASA) were measured by 3D-STI. The correlation of three-dimensional strain parameters with biochemical and ultrasonic parameters was analyzed. Results compared with the control group, the left atrial anterior and posterior diameter (lad) in the severe group was increased, and the mitral orifice diastolic velocity ratio (E / A) was decreased in the control group (P < 0.05). Compared with the control group, GLS, GAS in the mild group was lower than that in the control group, and the GLS, GRS, GCS, GAS and ASDI in the severe group were significantly higher than those in the control group (P < 0.05). Compared with mild group, GLS in severe group was significantly lower than that in mild group (P < 0.05). There was a negative correlation between GLS and Tei index, a negative correlation between GAS and LVEF, a positive correlation between GAS and LVEF, and a negative correlation between GAS and Tei index. There was a negative correlation between GAS and heart fatty acid binding protein H-FABP0.046, and a positive correlation with Tei index. Conclusion left ventricular systolic function is significantly impaired in preeclampsia patients. The 3D-STI technique can be used to evaluate the left ventricular systolic function in preeclampsia patients.
【作者單位】： 湖北省科技學院臨床醫(yī)學院超聲診斷教研室;咸寧市中心醫(yī)院神經(jīng)外科;
【分類號】：R445.1;R714.244

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