本文選題：乳腺占位性病變 + 擴(kuò)散加權(quán)成像��； 參考：《臨床放射學(xué)雜志》2017年05期

【摘要】：目的探討乳腺占位性病變內(nèi)液性信號(hào)區(qū)MRI表觀擴(kuò)散系數(shù)(ADC)值對(duì)病變性質(zhì)的鑒別診斷價(jià)值。方法回顧性分析內(nèi)含液性區(qū)并經(jīng)病理證實(shí)的54例乳腺疾病患者資料,根據(jù)其病理結(jié)果分為惡性腫瘤組(28例)、良性腫瘤組(13例)、炎性病變組(13例)。術(shù)前行MRI掃描,測(cè)量病變內(nèi)液性區(qū)域ADC值,并采用單因素方差分析,比較三組乳腺病變內(nèi)平均ADC值的差異性。采用受試者工作特征曲線(ROC)分析液性區(qū)ADC值對(duì)乳腺病變性質(zhì)的診斷效能。結(jié)果乳腺惡性腫瘤組、良性腫瘤組和炎性病變組液性區(qū)的ADC均值分別為(2.03±0.52)×10~(-3)mm~2/s、(1.99±0.56)×10~(-3)mm~2/s和(1.17±0.66)×10~(-3)mm~2/s,差異具有統(tǒng)計(jì)學(xué)意義(F=11.242,P0.01)。確定1.61×10~(-3)mm~2/s作為腫瘤性病變與炎性病變的鑒別診斷閾值時(shí),其診斷敏感度、特異度以及約登指數(shù)分別為83%、77%和0.60;取1.61×10~(-3)mm~2/s作為惡性腫瘤與炎性病變的鑒別診斷閾值時(shí),其診斷敏感度、特異度以及約登指數(shù)分別為89%、77%和0.66;采用1.32×10~(-3)mm~2/s作為鑒別良性占位性病變和炎性病變的診斷閾值時(shí),其診斷敏感度、特異度以及約登指數(shù)分別為85%、69%和0.54。結(jié)論乳腺占位性病變液性區(qū)ADC值對(duì)于乳腺惡性腫瘤與炎性病變的鑒別具有較高的應(yīng)用價(jià)值,能夠?yàn)榕R床診斷提供一條新的途徑。
[Abstract]:Objective to investigate the value of MRI apparent diffusion coefficient (MRI) in the fluid signal region of breast occupying lesions in the differential diagnosis of lesions.Methods the data of 54 patients with breast disease confirmed by pathology were retrospectively analyzed. According to the pathological results, they were divided into malignant tumor group (n = 28), benign tumor group (n = 13) and inflammatory lesion group (n = 13).Preoperative MRI scanning was performed to measure the ADC value in the fluid region of the lesion. The difference of the mean ADC value in the three groups was compared by single factor analysis of variance (ANOVA).The effectiveness of ADC value of fluid region in diagnosis of breast lesions was analyzed by means of operating characteristic curve (OC).The diagnostic sensitivity, specificity and Jordan index of 1. 61 脳 10~(-3)mm~2/s as the threshold for differential diagnosis of malignant and inflammatory lesions were 83 77% and 0. 60%, respectively, while 1. 61 脳 10~(-3)mm~2/s was used as the diagnostic threshold for the differential diagnosis of malignant and inflammatory lesions.The diagnostic sensitivity, specificity and Yorden index were 850.69% and 0.54 when 1.32 脳 10~(-3)mm~2/s was used as the diagnostic threshold for differentiating benign and inflammatory lesions.Conclusion the value of ADC in the fluid area of breast occupying lesions is of great value in the differential diagnosis of malignant and inflammatory lesions of breast, and it can provide a new way for clinical diagnosis.
【作者單位】： 廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;
【基金】：廣西壯族自治區(qū)科學(xué)技術(shù)廳科技攻關(guān)計(jì)劃項(xiàng)目(編號(hào):桂科攻14124004-1-11)
【分類號(hào)】：R445.2;R737.9

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 陳利華;陳永峰;張久權(quán);王文偉;夏云寶;王健;;表觀擴(kuò)散系數(shù)值在鑒別不同組織學(xué)類型肺癌中的價(jià)值[J];中國(guó)醫(yī)學(xué)影像技術(shù);2012年08期

2 潘希敏;魏富鑫;黎規(guī)典;;表觀擴(kuò)散系數(shù)在子宮惡性腫瘤診斷中的應(yīng)用價(jià)值[J];臨床醫(yī)學(xué)工程;2013年10期

3 A.F.Halaweish;E.A.Hoffman;D.R.Thedens;M.K.Fuld;J.P.Sieren;E.J.R.van Beek;王霽g;;不吸煙者肺膨脹水平對(duì)超極化~3He表觀擴(kuò)散系數(shù)測(cè)量的影響[J];國(guó)際醫(yī)學(xué)放射學(xué)雜志;2013年05期

4 王霈;張輝;蘇晉生;張華華;武瑞鳳;郭娟;王俊波;秦江波;;正常婦女乳腺不同月經(jīng)周期表觀擴(kuò)散系數(shù)差異的初探[J];中國(guó)藥物與臨床;2009年01期

5 管s，

本文編號(hào)：1736425