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實時剪切波彈性成像在不同大小TI-RADS 3~4類甲狀腺結節(jié)鑒別診斷中的應用

發(fā)布時間:2018-03-02 09:47

  本文關鍵詞: 剪切波彈性成像 甲狀腺結節(jié) TI-RADS ~類 出處:《南京醫(yī)科大學學報(自然科學版)》2017年02期  論文類型:期刊論文


【摘要】:目的:探討實時剪切波彈性成像(shear wave elastography,SWE)在不同大小甲狀腺TI-RADS 3~4類結節(jié)鑒別診斷中的應用。方法:常規(guī)超聲觀察164例患者(共197個結節(jié))甲狀腺結節(jié)的邊界、內部回聲、是否合并鈣化、縱橫比、內部及周邊血流情況等,依據甲狀腺TI-RADS分類方法對相應的甲狀腺狀腺結節(jié)進行分類,同時進行剪切波彈性成像,記錄結節(jié)楊氏模量最大值(Emax),繪制ROC曲線,獲得鑒別診斷甲狀腺良惡性結節(jié)的Emax最佳界值。其中TI-RADS 3~4類結節(jié)186個,分直徑≤10 mm組(Ⅰ組)和直徑10 mm組(Ⅱ組)。以病理結果為金標準,分別繪制ROC曲線,評價Emax值在Ⅰ、Ⅱ組病變中的應用價值。結果:楊氏模量Emax界值為52.5 k Pa。Ⅰ組和Ⅱ組的敏感性、準確性及特異性分別為57.4%、66.2%及90.0%和87.5%、79.5%及68.8%,ROC曲線下面積(area under the curve,AUC)分別為0.810和0.842。結論:SWE界值鑒別診斷甲狀腺良惡性結節(jié)差異有統(tǒng)計學意義;SWE對10 mm甲狀腺結節(jié)良惡性鑒別診斷更有應用價值;SWE對≤10 mm甲狀腺結節(jié)應用價值有限。
[Abstract]:Objective: to investigate the application of real-time shear wave elastography wave (ESR) in differential diagnosis of thyroid TI-RADS 3O 4 nodules of different sizes. Methods: the boundary and internal echo of thyroid nodules in 164 patients (197 nodule) were observed by conventional ultrasound. With or without calcification, aspect ratio, internal and peripheral blood flow, the thyroid gland nodules were classified according to the thyroid TI-RADS classification method, and the shear wave elastic imaging was performed at the same time. The maximum value of Young's modulus was recorded and the ROC curve was drawn to obtain the best value of Emax for differential diagnosis of benign and malignant thyroid nodules. The diameter 鈮,

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