發(fā)布時間：2018-03-02 09:18

  本文關(guān)鍵詞： 超聲檢查 足部肌肉 足底組織 2型糖尿病 周圍神經(jīng)病變　出處：《廣西醫(yī)科大學》2017年碩士論文　論文類型：學位論文

【摘要】：目的:探討高頻超聲在檢測2型糖尿病(T2DM)合并周圍神經(jīng)病變(DPN)患者足部肌肉和足底組織變化中的應用價值。方法:選取住院的T2DM患者60例,并分為兩組:T2DM合并DPN患者為DP組,30例;T2DM未合并DPN患者為DM組,30例。另收集健康志愿者25例作為對照(ND組)。應用高頻超聲檢查受檢者非優(yōu)勢足的趾短伸肌(EDB),第一、二跖趾間肌群(MIL)以及第一至第五跖骨頭下足底皮膚(表皮和真皮)、足底脂肪組織,測量EDB的厚度與橫截面,MIL及跖骨頭下足底皮膚、足底脂肪組織的厚度。應用t檢驗和秩和檢驗進行數(shù)據(jù)分析,以P0.05為差異有統(tǒng)計學意義。結(jié)果:DP組的EDB的厚度和橫截面積以及MIL的厚度較DM組、ND組均明顯減小(P均0.01); DM組的EDB橫截面積以及MIL厚度較ND組均明顯減小(P均0.01);DP組的EDB厚度和橫截面積以及MIL厚度較DM組均明顯減小于(P均0.01)。DP組、DM組的足底皮膚厚度較ND組均減小(P均0.05)。DP組的足底脂肪組織厚度較DM組、ND組均減小(P均0.05), DM組的足底脂肪組織厚度較ND組均減小(P均0.05)。結(jié)論:高頻超聲檢查能夠檢測到2型糖尿患者足部肌肉萎縮以及足底皮膚和脂肪組織變薄;2型糖尿病患者合并周圍神經(jīng)病變后肌肉萎縮和足底脂肪組織變薄程度加重。高頻超聲檢查可以客觀的顯示T2DM及合并DPN患者的足部肌肉萎縮和足底組織變薄。
[Abstract]:Objective: to investigate the value of high frequency ultrasound in detecting the changes of muscle and plantar tissue in patients with type 2 diabetes mellitus (T2DM) complicated with peripheral neuropathy (DPN). Two groups were divided into two groups: DP group (n = 30) with T2DM and DPN (n = 30) and healthy volunteers (n = 25) as control group (n = 30). High frequency ultrasound was used to examine the extensor digitorum brevis muscle of non-dominant foot. The thickness and cross section of EDB and the skin of the first to 5th metatarsal heads (epidermis and dermis, plantar adipose tissue) and the subplantar skin of the first to 5th metatarsal heads were measured. Thickness of plantar adipose tissue. Data analysis using t test and rank sum test. Results the thickness and cross-sectional area of EDB and the thickness of MIL in the group of EDB were significantly decreased than those in the group of DM and ND, and the cross-sectional area of EDB and the thickness of MIL in the group of DM were significantly lower than those in the group of ND, and the thickness of MIL in the group of DM was significantly lower than that in the group of ND. The thickness of EDB, cross sectional area and MIL in DM group were significantly lower than those in DM group. The thickness of plantar skin in DM group was significantly lower than that in ND group. The thickness of plantar adipose tissue in DM group was lower than that in ND group, and the thickness of plantar adipose tissue in DM group was lower than that in ND group, and the foot thickness in DM group was lower than that in DM group. Conclusion: high frequency ultrasound can detect foot muscle atrophy and skin and adipose tissue thinning in type 2 diabetic patients with peripheral neuropathy. High frequency ultrasound could objectively show the muscle atrophy and the thinning of plantar tissue in patients with T2DM and DPN.
【學位授予單位】：廣西醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R587.2;R445.1

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