單絨毛膜性雙胎臍帶附著位置與雙胎輸血綜合征、雙胎生長不一致及胎兒結(jié)構(gòu)畸形的相關(guān)性研究
發(fā)布時間:2018-01-25 16:58
本文關(guān)鍵詞: 單絨毛膜性雙胎 臍帶附著位置 雙胎輸血綜合癥 生長不一致 胎兒結(jié)構(gòu)畸形 出處:《東南大學學報(醫(yī)學版)》2017年04期 論文類型:期刊論文
【摘要】:目的:探討單絨毛膜性雙胎臍帶附著位置與雙胎輸血綜合征(TTTS)、雙胎生長不一致及胎兒結(jié)構(gòu)畸形的相關(guān)性。方法:自2010年10月至2016年10月行中晚孕超聲檢查單絨毛膜性胎兒共58例,每例胎兒均多切面掃查臍帶附著位置,回顧性分析臍帶附著位置異常雙胎中TTTS、胎兒生長不一致及胎兒結(jié)構(gòu)畸形的發(fā)生率。結(jié)果:58例單絨毛膜性雙胎中雙胎之一臍帶為邊緣性或帆狀附著胎盤者共9例,均出現(xiàn)不同程度TTTS。雙胎之一臍帶附著位置近胎盤邊緣13例,其中8例出現(xiàn)胎兒生長不一致,另5例胎兒生長發(fā)育參數(shù)無明顯差異。胎兒嚴重結(jié)構(gòu)異常4例,輕度結(jié)構(gòu)異常10例,結(jié)構(gòu)異常胎兒中僅1例胎兒臍帶邊緣附著。結(jié)論:單絨毛膜性雙胎之一臍帶附著位置為邊緣性或帆狀附著與TTTS有明確相關(guān)性;臍帶附著近胎盤邊緣與胎兒生長不一致的發(fā)生有一定關(guān)系,但不是決定性因素;臍帶附著位置異常與胎兒畸形無明確相關(guān)性。
[Abstract]:Objective: to investigate the position of umbilical cord attachment and TTS in single chorionic twins. Methods: from October 2010 to October 2016, 58 cases of single chorionic fetus were examined by ultrasound from October 2010 to October 2016. The location of umbilical cord attachment was examined by multi-sectional scanning in each fetus. The TTTS in the twins with abnormal umbilical cord attachment was analyzed retrospectively. Results 9 of 58 single chorionic twins with marginal or sail placenta attached to one of the twin chorionic twins. There were 13 cases of umbilical cord attachment near the placenta edge, 8 of which showed fetal growth inconsistency. All of them had different degrees of TTTS.There were 13 cases of umbilical cord attachment near the edge of placenta. There was no significant difference in the parameters of fetal growth and development in the other 5 cases. There were severe structural abnormalities in 4 cases and mild structural abnormalities in 10 cases. Only one fetus with abnormal structure attached to the edge of umbilical cord. Conclusion: the location of umbilical cord attachment in single chorionic twins is marginal or sails, and there is a clear correlation between umbilical cord attachment and TTTS. There is a certain relationship between umbilical cord attachment near the placental edge and the occurrence of fetal growth inconsistency, but it is not a decisive factor. There was no clear correlation between abnormal attachment of umbilical cord and fetal malformation.
【作者單位】: 中國人民解放軍第一五三中心醫(yī)院超聲科;中國人民解放軍第一五三中心醫(yī)院婦產(chǎn)科;鄭州大學第一附屬醫(yī)院超聲科;
【分類號】:R445.1;R714.5
【正文快照】: 近年來,隨著人口出生率的增加,各種人工輔助生殖技術(shù)的應用,雙胎妊娠率不斷上升。雙胎妊娠的風險較單胎妊娠風險大,特別是單絨毛膜性(MC)雙胎。MC雙胎在所有妊娠中的發(fā)病率為1/400,屬于高危妊娠,胎兒丟失率及圍產(chǎn)期病死率較高[1]。雙胎輸血綜合征(TTTS)是MC雙胎的嚴重并發(fā)癥,,
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