發(fā)布時間：2019-02-14 13:34

【摘要】：在頻域光學(xué)相干層析(Spectral Domain Optical Coherence Tomography,SDOCT)系統(tǒng)中,為了在橫向和縱向兩個方向均獲得高的分辨率,需要采用大數(shù)值孔徑的物鏡。這時,僅位于物鏡焦深范圍內(nèi)的結(jié)構(gòu)有高橫向分辨率,在焦外分辨率降低。干涉合成孔徑顯微術(shù)(ISAM)是一種三維圖像重構(gòu)算法,可以消除離焦區(qū)的圖像模糊,達到在所有成像深度中都可以獲得焦平面處的橫向分辨率的效果,可以解決SDOCT中系統(tǒng)的橫向分辨率和成像深度之間的矛盾。本文分析了 ISAM重構(gòu)算法的原理和適用的范圍,對比分析了傳統(tǒng)SDOCT成像算法和經(jīng)過ISAM重構(gòu)算法處理的成像圖像結(jié)果。為了減少算法運算時間,本文將非均勻傅里葉變換(NUFFT)引入了 ISAM算法,實驗結(jié)果表明了該方法節(jié)省了算法的運算時間,給實時成像高分辨率SDOCT系統(tǒng)成像提供了基礎(chǔ)。其次,為了檢測光學(xué)元件的亞表面損傷,將全內(nèi)反射法(TIRM)和SDOCT兩套系統(tǒng)聯(lián)合來進行檢測和評估分析,本文提出了一套標(biāo)定和測量的方法并進行了實驗。實驗通過標(biāo)定雙系統(tǒng)的探測臂位置使之可以對同一點先進行粗定位后進行精確的層析成像,得到對亞表面損傷進行表征的參數(shù)。
[Abstract]:In the frequency-domain optical coherence tomography (Spectral Domain Optical Coherence Tomography,SDOCT) system, in order to obtain high resolution in both transverse and longitudinal directions, a large numerical aperture objective is needed. In this case, the structure located within the focal depth of the objective lens has a high lateral resolution and a lower resolution outside the focal point. Interferometric synthetic aperture microscopy (ISAM) is a 3D image reconstruction algorithm, which can eliminate the image blur in the defocus region and achieve the effect that the horizontal resolution of the focal plane can be obtained in all imaging depths. It can solve the contradiction between lateral resolution and imaging depth in SDOCT. In this paper, the principle and application range of ISAM reconstruction algorithm are analyzed, and the results of traditional SDOCT imaging algorithm and image processed by ISAM reconstruction algorithm are compared and analyzed. In order to reduce the computational time of the algorithm, the non-uniform Fourier transform (NUFFT) is introduced into the ISAM algorithm. The experimental results show that the algorithm saves the computation time and provides the basis for real-time imaging of high-resolution SDOCT system. Secondly, in order to detect the subsurface damage of optical elements, the total internal reflection method (TIRM) and SDOCT are combined to detect and evaluate the subsurface damage. In this paper, a set of calibration and measurement methods are proposed and the experiments are carried out. By calibrating the position of the detecting arm of the two systems, the parameters of the subsurface damage can be obtained by the initial coarse location of the same point and the accurate tomography.
【學(xué)位授予單位】：南京理工大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：TP391.41

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