本文選題：胚胎停育　切入點：染色體異常　出處：《實用醫(yī)學(xué)雜志》2017年22期

【摘要】：正胚胎停育是指妊娠早期胚胎停止發(fā)育、丟失的病理過程,多發(fā)生在妊娠7~10周,近年來發(fā)病率呈上升趨勢。導(dǎo)致胚胎停育的因素很多,其中主要是因為胚胎染色體異常~([1]),胚胎停育的絨毛染色體異常率可達(dá)50%~70%~([2]),實際上由于受到檢測方法準(zhǔn)確性的制約,染色體的異常可能明顯高于這個比例。而精確檢測流產(chǎn)組織核型,有利于尋找胚胎停育病因、評估預(yù)后及指導(dǎo)后續(xù)的治療。目前國內(nèi)普遍
[Abstract]:Normal embryo arrest is a pathological process in which the embryo stops developing and loses in the first trimester of pregnancy. Most of the pathological processes occur at the 7th week of gestation, the incidence of which is increasing in recent years, and there are many factors leading to the termination of embryo. This is mainly due to the chromosomal abnormalities of embryos ([1]), the abnormal rate of chromosomes in the villi of embryos that are suspended can reach 50% and 70% (2), which is actually restricted by the accuracy of the detection methods. Chromosomal abnormalities may be significantly higher than this ratio. Accurate detection of the karyotype of abortive tissues is beneficial to finding the etiology, evaluating the prognosis and guiding the subsequent treatment of embryo stoppage. At present, it is common in China to detect the karyotype of abortive tissues.
【作者單位】： 上海交通大學(xué)附屬第六人民醫(yī)院生殖醫(yī)學(xué)中心;
【基金】：上海市衛(wèi)生和計劃生育委員會科研課題(編號:201440004)
【分類號】：R440;R714.2
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本文編號：1684218