本文選題：汽化過(guò)氧化氫發(fā)生器 + Polyethylene　； 參考：《江南大學(xué)》2017年碩士論文

【摘要】：滅菌在無(wú)菌灌裝過(guò)程中是十分重要的環(huán)節(jié),直接影響產(chǎn)品的質(zhì)量,汽化過(guò)氧化氫滅菌技術(shù)在國(guó)外已作為一種新型綠色滅菌方法用于無(wú)菌灌裝生產(chǎn)中。而我國(guó)汽化過(guò)氧化氫滅菌技術(shù)還處于起步階段,其生成設(shè)備與國(guó)外設(shè)備也有很大的差距,因此開(kāi)發(fā)新型的汽化過(guò)氧化氫生成設(shè)備對(duì)提高我國(guó)無(wú)菌包裝技術(shù)具有非常重要的現(xiàn)實(shí)意義。本文對(duì)汽化過(guò)氧化氫發(fā)生器進(jìn)行了設(shè)計(jì),并通過(guò)實(shí)驗(yàn)研究了汽化過(guò)氧化氫生成工藝參數(shù)和操作工況對(duì)滅菌效果的影響,主要研究?jī)?nèi)容如下:1.基于文丘里原理,選擇文丘里管射流器作為霧化部件,采用先混合霧化后加熱的方法制備汽化過(guò)氧化氫。對(duì)汽化過(guò)氧化氫發(fā)生器的主體結(jié)構(gòu)、氣液混合及加熱系統(tǒng),流量和溫度控制系統(tǒng)各組成部分進(jìn)行了研究設(shè)計(jì)。對(duì)文丘里管射流器進(jìn)行了理論計(jì)算,并通過(guò)霧化試驗(yàn)對(duì)射流器進(jìn)行了驗(yàn)證。對(duì)加熱器的加熱功率進(jìn)行了計(jì)算,選擇總功率為6kW的加熱器,并采用2 kW和4 kW串聯(lián)的方法實(shí)現(xiàn)對(duì)霧化過(guò)氧化氫加熱和溫度控制。2.采用單因素和響應(yīng)面實(shí)驗(yàn)結(jié)合法研究了汽化過(guò)氧化氫在“未預(yù)熱-滅菌-不吹干”工況下對(duì)Polyethylene Terephthalate(PET)瓶坯內(nèi)表面枯草芽孢桿菌的殺菌效果。由單因素實(shí)驗(yàn)可得,H_2O_2流量和滅菌時(shí)間與殺菌效果呈正相關(guān),隨溶液流量的增加、滅菌時(shí)間的延長(zhǎng),殺菌效果明顯增強(qiáng);而蒸汽溫度與滅菌效果呈負(fù)相關(guān),隨溫度的升高,過(guò)氧化氫分解加劇使得滅菌效果減弱。在此工況下,由響應(yīng)面實(shí)驗(yàn)得出,H_2O_2流量和滅菌時(shí)間的交互作用對(duì)滅菌效果的影響較大,根據(jù)回歸分析結(jié)果得出最佳工藝參數(shù)為:H_2O_2溶液流量16 m L/min,滅菌時(shí)間10 s,蒸汽溫度120℃,經(jīng)驗(yàn)證,測(cè)得在此工藝條件下生成的汽化過(guò)氧化氫對(duì)PET瓶坯中枯草芽孢桿菌的殺菌對(duì)數(shù)值可達(dá)6.85-log(CFU/m L)。3.研究了汽化過(guò)氧化氫在工業(yè)工況(50℃預(yù)熱-滅菌-50℃熱風(fēng)干燥)下對(duì)PET瓶坯內(nèi)表面枯草芽孢桿菌的殺菌效果。在單因素的基礎(chǔ)上,通過(guò)響應(yīng)面優(yōu)化實(shí)驗(yàn)建立了H_2O_2溶液流量、滅菌時(shí)間和蒸汽溫度對(duì)殺菌對(duì)數(shù)值的三元二次回歸方程,經(jīng)分析得出,H_2O_2溶液流量和滅菌時(shí)間的交互作用對(duì)滅菌效果的影響非常顯著,此工況的最佳工藝參數(shù)為:H_2O_2溶液流量14.24 m L/min,滅菌時(shí)間9.05 s,蒸汽溫度120℃,該條件下預(yù)測(cè)滅菌值為5.45-log(CFU/m L),實(shí)驗(yàn)滅菌平均值為5.39-log(CFU/mL)。為保證徹底滅菌,提高H_2O_2溶液流量進(jìn)行試驗(yàn),結(jié)果發(fā)現(xiàn)隨過(guò)氧化氫溶液流量的增大,汽化過(guò)氧化氫殺菌效果明顯增強(qiáng)。本課題提供了一種汽化過(guò)氧化氫發(fā)生器的設(shè)計(jì)方法,通過(guò)對(duì)汽化過(guò)氧化氫滅菌工藝參數(shù)和效果的研究,證明了汽化過(guò)氧化氫滅菌技術(shù)具有效率高,H_2O_2溶液用量少的優(yōu)勢(shì),在無(wú)菌灌裝中具有很好的應(yīng)用價(jià)值。
[Abstract]:Sterilization is a very important link in the process of aseptic filling, which directly affects the quality of products. Vaporization of hydrogen peroxide sterilization technology has been used as a new green sterilization method in aseptic filling production abroad. However, the vaporization of hydrogen peroxide sterilization technology in China is still in its infancy, and its generating equipment is far from that of foreign countries. Therefore, the development of new vaporized hydrogen peroxide production equipment is of great practical significance to improve the aseptic packaging technology in China. In this paper, the vaporization hydrogen peroxide generator is designed, and the effects of the process parameters and operating conditions on the sterilizing effect are studied experimentally. The main research contents are as follows: 1. Based on Venturi principle, Venturi tube jet was selected as atomizing component to prepare vaporized hydrogen peroxide by mixing atomization and heating. The main structure of vaporized hydrogen peroxide generator, gas-liquid mixing and heating system, flow rate and temperature control system are studied and designed. The theoretical calculation of Venturi tube jet was carried out, and the atomization test was carried out to verify the jet. The heating power of the heater is calculated. The heater with total power of 6kW is selected, and the atomized hydrogen peroxide heating and temperature control. 2 kW and 4 kW in series are adopted. The bactericidal effect of vaporized hydrogen peroxide on Bacillus subtilis (Bacillus subtilis) on the inner surface of Polyethylene Terephthalate (PET) flask was studied by single factor and response surface test. From the single factor experiment, it was found that the volume of H2O2 and sterilizing time were positively correlated with the bactericidal effect. With the increase of the solution flow rate, the sterilization time increased obviously, while the steam temperature was negatively correlated with the sterilizing effect and increased with the increase of the temperature. The decomposition of hydrogen peroxide weakens the sterilizing effect. Under this condition, the interaction between the flow rate and sterilizing time was found to have a great influence on the sterilizing effect. According to the regression analysis, the optimum technological parameters were as follows: flow rate 16ml / min, sterilizing time 10s, steam temperature 120 鈩，

本文編號(hào)：1914170