【摘要】：第一章:成功的合成氮乙酰-L-半胱氨酸(NALC-Au NPs),并將其用于電化學(xué)阻抗傳感器的構(gòu)建,實(shí)現(xiàn)了酪氨酸的手性識別。此傳感器基于L-和D-酪氨酸與傳感界面的作用不同,而導(dǎo)致電化學(xué)阻抗值產(chǎn)生差異,從而實(shí)現(xiàn)對酪氨酸手性識別。與其它方法相比,電化學(xué)阻抗傳感器更加高效、準(zhǔn)確,并且有寬的檢測范圍(10-769μmol·L-1)。另外,考察了NALC-Au NPs、酪氨酸的電沉積圈數(shù)、溶液p H、酪氨酸的濃度等對酪氨酸手性識別的影響。該方法將在醫(yī)藥領(lǐng)域中酪氨酸的手性識別方面有潛在的應(yīng)用價(jià)值。第二章:成功合成了羧甲基-β-環(huán)糊精保護(hù)的石墨烯負(fù)載金納米雜化材料(Au NPs-COOH-CH_3-β-CD-GNs),并將其修飾到玻碳電極表面,用于酪氨酸的手性識別。該材料結(jié)合了石墨烯、金納米良好的導(dǎo)電性及環(huán)糊精手性識別的特性,對酪氨酸對映異構(gòu)體有良好的手性識別效果。且當(dāng)酪氨酸緩沖溶液p H為5.0、濃度為566μmol/L、Au NPs-COOH-CH_3-β-CD-GNs修飾量為6μL、孵化時(shí)間為5分鐘時(shí),Au NPs-COOH-CH_3-β-CD-GNs/GCE傳感界面對酪氨酸的手性識別效果最佳。第三章:合成了β-環(huán)糊精功能化的石墨烯納米材料(β-CD-GNs),考察了其作為一種新型高效吸附劑對水中酸性大紅G(ASG)和橙黃Ⅱ(OrangeⅡ)的吸附性能。該材料結(jié)合了石墨烯和β-環(huán)糊精的特性,表現(xiàn)出對上述兩種染料良好的吸附性能,吸附平衡時(shí)間小于3 min,吸附率達(dá)90%以上,β-CD-GNs對ASG和OrangeⅡ的最大吸附量為622.2 mg·L-1和534.7 mg·L-1。另外,考察了β-CD-GNs用量、溶液p H、反應(yīng)溫度對吸附效果的影響。結(jié)果表明,當(dāng)溶液p H值為6.0、β-CD-GNs濃度為25 mg·L-1時(shí),吸附率最大,而且吸附率隨反應(yīng)溫度升高而降低。通過對吸附數(shù)據(jù)進(jìn)行線性擬合發(fā)現(xiàn),β-CD-GNs對ASG和OrangeⅡ的吸附等溫線符合Langmuir吸附等溫模型。該材料在印染廢水的處理領(lǐng)域有潛在的應(yīng)用價(jià)值。
[Abstract]:In chapter 1, N-acetyl-L-cysteine (NALC-Au NPs),) was successfully synthesized and applied to the construction of electrochemical impedance sensor (EIS) to realize the chiral recognition of tyrosine. Based on the difference of the interaction between L-and D-tyrosine and the sensing interface, the sensor results in the difference of electrochemical impedance, thus the chiral recognition of tyrosine can be realized. Compared with other methods, electrochemical impedance sensor is more efficient, accurate and has a wide detection range (10-769 渭 mol 路L-1). In addition, the effects of the number of electrodeposition cycles, the solution pH and the concentration of tyrosine on the chiral recognition of tyrosine in NALC-Au NPs, were investigated. This method will have potential application value in chiral recognition of tyrosine in medicine field. In chapter 2, carboxymethyl-尾-cyclodextrin protected graphene supported gold nano-hybrid material (Au NPs-COOH-CH_3- 尾-CD-GNs) was synthesized and modified to glassy carbon electrode surface for chiral recognition of tyrosine. The material combines graphene, gold nanoparticles with good conductivity and chiral recognition properties of cyclodextrin, and has a good chiral recognition effect on tyrosine enantiomers. And when the pH value of tyrosine buffer solution is 5.0, the concentration of au NPs-COOH-CH_3- 尾-CD-GNs is 566 渭 mol / L, and the incubation time is 5 minutes, the modification amount of au tyrosine 尾-mol / L is 6 渭 L, and the incubation time is 5 minutes. The chiral recognition effect of Au NPs-COOH-CH_3- 尾-CD-GNs/GCE sensing interface on tyrosine is the best. In chapter 3, 尾-cyclodextrin functionalized graphene nanomaterials (尾-CD-GNs) were synthesized and the adsorption properties of 尾-cyclodextrin functionalized graphene nano-materials for acidic red G (ASG) and orange 鈪，

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