【摘要】：熒光銀納米簇具有獨特的物理及化學性質,憑借合成簡便、熒光強度大、量子產率高、抗光漂白能力強、熒光發(fā)射波長可調及生物相容性好等優(yōu)勢,近年來在生物檢測、成像分析等領域受到了越來越廣泛的關注.文章基于DNA調控熒光銀納米簇的合成方法研究,綜述了關于DNA序列、長度、二級結構等對銀納米簇熒光性質的影響規(guī)律,并詳細介紹熒光銀納米簇在分析檢測和生物成像應用方面的最新進展.相信隨著熒光納米簇材料的應用優(yōu)勢逐步凸顯,該領域的研究將吸引更廣泛的關注,并推動相關交叉學科的進展.
[Abstract]:Due to its unique physical and chemical properties, fluorescent silver nanoclusters have many advantages such as simple synthesis, high fluorescence intensity, high quantum yield, strong photobleaching resistance, adjustable fluorescence emission wavelength and good biocompatibility. Imaging analysis and other fields have attracted more and more attention. Based on the synthesis of silver nanoclusters regulated by DNA, the effects of DNA sequence, length and secondary structure on the fluorescence properties of silver nanoclusters are reviewed. The latest development of fluorescent silver nanoclusters in analytical detection and bioimaging applications is also introduced in detail. It is believed that with the application advantages of fluorescent nanoclusters gradually prominent, the research in this field will attract more attention and promote the development of related interdisciplinary disciplines.
【作者單位】： 華南師范大學生物光子學研究院激光生命科學教育部重點實驗室;
【基金】：國家自然科學基金項目(21475048) 廣東省自然科學杰出青年科學基金(2014A030306008) 廣東省特支計劃(2014TQ01R559) 華南師范大學青年教師科研培育基金項目(671074)
【分類號】：O657.3

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