【摘要】：目的建立電感耦合等離子體質(zhì)譜(ICP-MS)法測定朱砂安神丸中可溶性汞的含有量。方法采用人工胃液保溫浸提及超聲提取法制備供試品溶液,ICP-MS法測定可溶性汞的含有量。結果可溶性汞在0~20.0 g/L范圍內(nèi)呈良好的線性關系,檢測限為0.04 g/L,定量限為0.13 g/L,3種質(zhì)量濃度的平均加樣回收率分別為94.7%、110.4%和92.3%,RSD分別為1.3%、1.0%和3.6%。結論該方法可用于朱砂安神丸中可溶性汞含有量的測定,為其質(zhì)量評價提供科學依據(jù)。
[Abstract]:Objective to establish an inductively coupled plasma mass spectrometry (ICP-MS) method for the determination of soluble mercury in Zhusa Anshen pills. Methods artificial gastric juice extraction and ultrasonic extraction were used to prepare the sample solution and ICP-MS method was used to determine the content of soluble mercury. Results the linear range of soluble mercury was 0 ~ 20.0 g / L, the detection limit was 0.04 g 路L ~ (-1) and the average recoveries of 0.13 g / L ~ (-1) g 路L ~ (-1) 路L ~ (-1) 路L ~ (-1) 路L ~ (-1) of soluble mercury were 94.77% and 92.3%, respectively, and the RSD were 1.3% and 3.6%, respectively. Conclusion the method can be used to determine the content of soluble mercury in Zhusa Anshen pills and provide scientific basis for its quality evaluation.
【作者單位】： 北京市藥品檢驗所中藥成分分析與生物評價北京市重點實驗室;
【基金】：北京市優(yōu)秀人才培養(yǎng)資助青年骨干個人項目(2015)
【分類號】：R286.0;O657.63
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本文編號：2140398