疏肝和胃護(hù)膜法治療肝胃不和型膽汁反流性胃炎的理論及臨床研究
[Abstract]:Objective: to observe the clinical effect of Chaishao protective membrane decoction, which was created by professor Shan Zhaowei, on the basis of soothing liver and stomach protective membrane, in the treatment of hepatogastric bile reflux gastritis (bile reflux gastritis,BRG), and to provide a new idea and method for clinical treatment of BRG. Methods: 1 theoretical research: it is divided into the study of etiology and pathogenesis, diagnosis and treatment of BRG in modern medicine and the study of disease name, etiology and pathogenesis, syndrome differentiation, treatment principle and treatment of BRG in traditional Chinese medicine. 2 Clinical study: 60 patients with hepatogastric disharmony type BRG were randomly divided into experimental group (n = 30) and control group (n = 30). The experimental group (n = 30) was treated with mosapride citrate dispersible tablet and magnesium aluminum carbonate tablet for 8 weeks. The clinical data, symptom score and bile reflux degree under gastroscopy were statistically analyzed by SPSS16.0. Results: before treatment, there was no significant difference in sex, age, symptom distribution and bile reflux degree between the two groups (P 0.05), indicating that the two groups were comparable, and there were no adverse reactions between the two groups. After treatment, the symptoms of the two groups were improved to varying degrees, and the improvement of the main symptoms (epigastric distension, pain or fullness, belching and acid ingestion, hiccup, nausea and vomiting, stomach noise) was the same between the two groups; there were differences in the improvement of secondary symptoms (lack of food, loose stools, depression or irritability, bitter mouth and mouth) between the two groups (P 0.05), and the experimental group was superior to the control group in improving the secondary symptoms (lack of food, loose stools, depression or irritability, bitter mouth, dry mouth and mouth). The total effective rates of the experimental group and the control group were 86.7% and 63.3%, respectively. Compared with the two groups, the curative effect of TCM syndrome in the experimental group was better than that in the control group. Conclusion: Fangchai Shaohumembrane decoction has a good clinical effect on the treatment of liver-stomach disharmony BRG, has obvious advantages in improving the overall symptoms of the patients, can improve the overall quality of life of the patients, and has a good clinical application prospect.
【學(xué)位授予單位】:南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R259
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