【摘要】：目的:觀察柴胡加龍骨牡蠣湯加減方治療痰熱內(nèi)擾型失眠癥的短期療效。方法:選擇100例失眠痰熱內(nèi)擾證患者,隨機分為治療組(柴胡加龍骨牡蠣湯加減方)51例、對照組(唑吡坦)49例。兩組均采用匹茲堡睡眠質(zhì)量指數(shù)(PSQI)、中醫(yī)證候總分評定療效,療程為2周。結(jié)果:治療組的總有效率90.20%,優(yōu)于對照組的81.63%(P0.05),其PSQI總分、中醫(yī)證候總分在治療1周后,2周后均明顯低于對照組(P0.01),"寐而易醒""多夢""心煩""胸悶""口苦""頭暈"6個癥狀積分低于對照組(P0.05);不良反應(yīng)發(fā)生率差異無統(tǒng)計學(xué)意義,但治療組起效時間晚于對照組(P0.01)。結(jié)論:柴胡加龍骨牡蠣湯加減方治療痰熱內(nèi)擾型失眠癥的短期療效確切,不良反應(yīng)少,值得推廣。
[Abstract]:Objective: to observe the short-term curative effect of chaihu plus Longgu oyster decoction in treating phlegm-heat internal disturbance insomnia. Methods: 100 patients with internal disturbance of insomnia and phlegm heat were randomly divided into treatment group (51 cases) and control group (49 cases). The two groups were treated with Pittsburgh Sleep quality Index (PSQI),) for 2 weeks. Results: the total effective rate of the treatment group was 90.20%, which was better than that of the control group (81.63%, P0.05). The total score of PSQI and TCM syndromes in the treatment group was significantly lower than that in the control group after 1 week treatment and 2 weeks after treatment (P0.01). The scores of 6 symptoms of "sleep and easy waking", "more dreams", "upset", "chest tightness", "bitter mouth" and "dizziness" were lower than those in the control group (P0.05). There was no significant difference in the incidence of adverse reactions, but the effective time in the treatment group was later than that in the control group (P 0.01). Conclusion: the short-term curative effect of chaihu plus Longgu oyster decoction in treating phlegm-heat internal disturbance insomnia is definite, the adverse reaction is few, and it is worth popularizing.
【作者單位】： 北京中醫(yī)藥大學(xué)東方醫(yī)院康復(fù)科;北京中醫(yī)藥大學(xué)東方醫(yī)院腦病二科;
【基金】：北京市科技計劃課題(No.Z13110200680000) 北京中醫(yī)藥大學(xué)東方醫(yī)院人才培養(yǎng)計劃項目(東方新星)(No.DFRC2014C01)~~
【分類號】：R256.23

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