【摘要】：目的:黃褐斑是臨床上常見的損美性疾病之一,雖極少有自覺不適癥狀,但病情遷延日久,給患者身心造成極大的困擾。本次研究通過觀察中西醫(yī)結(jié)合治療肝郁氣滯型黃褐斑的療效,以客觀的角度分析中西醫(yī)內(nèi)外治法相結(jié)合的療效,為黃褐斑的治療方法提供參考依據(jù)。材料與方法:本次研究的56例黃褐斑患者均選自于2015年3月至2016年9月期間,就診于遼寧中醫(yī)藥大學(xué)附屬醫(yī)院皮膚科門診患者。采用隨機分組法,將患者分為治療組(逍遙散加減100ml日2次口服,圍刺法以及維生素C100mg、維生素E100mg日3次口服)和對照組(維生素C、維生素E口服聯(lián)合針灸圍刺法),各28例。兩組均以4周為一個療程,共兩個療程。觀察并記錄每個療程末兩組患者的癥狀。結(jié)果:1.第一療程結(jié)束時,治療組總有效率為35.71%,對照組總有效率為39.29%,兩組患者MASI評分(P=0.7830.05),療效差異不存在統(tǒng)計學(xué)意義。表明兩組治療方法療效相似。2.療程結(jié)束時,治療組總有效率為88.89%,對照組總有效率為57.69%,兩組患者MASI評分(P=0.010.05),療效差異存在統(tǒng)計學(xué)意義。表明治療組治療方法具有更好療效。3.兩個月后隨訪一次,兩組患者評分均有所升高,但總體治療組低于對照組。隨訪結(jié)果:治療組復(fù)發(fā)率為27.27%,對照組復(fù)發(fā)率為64.29%,表明對照組的復(fù)發(fā)率高于治療組。結(jié)論:1、逍遙散加減可有效改善肝郁氣滯型黃褐斑患者的癥狀。2、逍遙散加減、圍刺法結(jié)合維生素C及維生素E能夠有效縮小肝郁氣滯型黃褐斑患者的皮損面積及使斑片顏色變淺。3、逍遙散加減、圍刺法結(jié)合維生素C及維生素E治療肝郁氣滯型黃褐斑效果優(yōu)于維生素C及維生素E聯(lián)合針灸圍刺法治療的療效,值得臨床推廣應(yīng)用。
[Abstract]:Objective: chloasma is one of the most common diseases in clinic. Although there are few symptoms of malaise, the disease is prolonged for a long time. In this study, we observed the curative effect of combination of traditional Chinese and western medicine in treating chloasma with stagnation of liver and qi, and analyzed the curative effect of combination of internal and external treatment of traditional Chinese and western medicine in order to provide reference for the treatment of chloasma. Materials and methods: 56 cases of chloasma were selected from March 2015 to September 2016. The patients were randomly divided into two groups: treatment group (Xiaoyao Powder plus or subtractive 100ml twice daily, peri-acupuncture and vitamin C 100mg, vitamin E 100mg 3 times) and control group (vitamin C, vitamin E oral combined with acupuncture and moxibustion). Each 28 cases. The two groups were given 4 weeks as a course of treatment, a total of two courses of treatment. The symptoms of the two groups were observed and recorded at the end of each course. Results: 1. At the end of the first course of treatment, the total effective rate was 35.71 in the treatment group and 39.29 in the control group. The MASI score of the two groups was 0.7830.05. The results showed that the therapeutic effects of the two groups were similar. 2. 2. At the end of the course of treatment, the total effective rate of the treatment group was 88.89 and the total effective rate of the control group was 57.69. The MASI score of the two groups was 0.010.05, and the difference was statistically significant. The results showed that the treatment group had better curative effect. 3. After two months follow-up, the scores of both groups increased, but the overall treatment group was lower than the control group. The follow-up results showed that the recurrence rate was 27.27 in the treatment group and 64.29 in the control group, indicating that the recurrence rate in the control group was higher than that in the treatment group. Conclusion: 1, Xiaoyao San can effectively improve the symptoms of chloasma with stagnation of liver and qi. The peri-acupuncture method combined with vitamin C and vitamin E can effectively reduce the area of skin lesions and make the spots shallower in the patients with chloasma with stagnation of liver-qi, and add and subtract Xiaoyao San. The efficacy of peri-acupuncture combined with vitamin C and vitamin E in the treatment of chloasma with stagnation of liver-qi was better than that of vitamin C and vitamin E combined with acupuncture and moxibustion.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R275.9

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