【摘要】：目的:探討針灸結(jié)合中藥治療退變性下頸椎不穩(wěn)患者臨床療效及對(duì)血管活性因子的影響,為臨床研究提供參考依據(jù)。方法:選擇2013年1月—2015年12月120例退變性下頸椎不穩(wěn)患者作為研究對(duì)象,采用隨機(jī)數(shù)字表法分為觀察組與對(duì)照組各60例,分別給予針灸結(jié)合中藥治療與單獨(dú)針灸治療,所有患者均治療30 d,比較兩組療效,并抽取空腹血檢測(cè)治療前后血管活性因子一氧化氮(NO)及內(nèi)皮素(ET)水平變化。結(jié)果:觀察組總有效率95.0%明顯高于對(duì)照組83.3%,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。治療后兩組臨床癥狀構(gòu)成比均明顯降低,差異有統(tǒng)計(jì)學(xué)意義(P0.05);觀察組降低更明顯(P0.05)。觀察組治療后ET為(64.52±12.47)ng/L,NO為(38.54±9.99)μmmol/L,與治療前比較ET(88.89±12.92)ng/L,NO(62.64±10.11)μmmol/L,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。對(duì)照組治療后ET為(73.44±12.25)ng/L,NO為(47.84±10.12)μmmol/L,明顯低于治療前(88.90±14.21)ng/L,(62.41±9.72)μmmol/L,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。且治療后觀察組明顯低于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:針灸聯(lián)合中藥治療退變性下頸椎不穩(wěn)患者有更好的臨床療效,在有效改善患者癥狀的同可時(shí)以更明顯降低血管活性因子。
[Abstract]:Objective: to explore the clinical effect of acupuncture and moxibustion combined with traditional Chinese medicine on degenerative cervical spine instability and its influence on vasoactive factors. Methods: from January 2013 to December 2015, 120 patients with degenerative lower cervical vertebra instability were divided into two groups: observation group (n = 60) and control group (n = 60). Acupuncture and moxibustion combined with traditional Chinese medicine and acupuncture alone were used respectively. All patients were treated for 30 days to compare the efficacy of the two groups. Fasting blood samples were taken to detect the changes of nitric oxide (NO) and endothelin (ET) levels before and after treatment. Results: the total effective rate in the observation group was 95.0% significantly higher than that in the control group (83.3%, P0.05). After treatment, the clinical symptom composition ratio of the two groups were significantly decreased, the difference was statistically significant (P0.05); the observation group decreased more significantly (P0.05). After treatment, the ET of the observation group was (64.52 鹵12.47) ng/L,NO (38.54 鹵9.99) 渭 mmol/L, which was significantly higher than that of the pre-treatment ET (88.89 鹵12.92) ng/L,NO (62.64 鹵10.11) 渭 mmol/L, (P0.05). The ET of the control group was (73.44 鹵12.25) ng/L,NO (47.84 鹵10.12) 渭 mmol/L, significantly lower than that of the pre-treatment (88.90 鹵14.21) ng/L, (62.41 鹵9.72) 渭 mmol/L, (P0.05). And the observation group after treatment was significantly lower than the control group, the difference was statistically significant (P0.05). Conclusion: acupuncture and moxibustion combined with traditional Chinese medicine are more effective in treating degenerative lower cervical spine instability.
【作者單位】： 貴州醫(yī)科大學(xué)附屬醫(yī)院中醫(yī)科;
【基金】：國家中醫(yī)藥管理局名老中醫(yī)傳承工作室建設(shè)項(xiàng)目(2014)
【分類號(hào)】：R274.9

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