【摘要】：目的探討中醫(yī)六君子湯合桃紅四物湯加味治療高尿酸血癥(HUA)的臨床效果。方法將60例HUA患者隨機(jī)分為2組各30例,所有患者給予常規(guī)治療,觀察組在此基礎(chǔ)上加用六君子湯合桃紅四物湯加味治療。12周后觀察2組血尿酸(UA)、血壓、三酰甘油(TG)、空腹血糖(FPG)、糖化血紅蛋白(Hb A1c)、體質(zhì)量指數(shù)的變化情況,并評(píng)價(jià)臨床療效。結(jié)果治療后對(duì)照組血清UA水平較治療前無明顯變化(P0.05),而觀察組UA水平較治療前明顯降低(P0.05),且明顯低于對(duì)照組(P0.05);觀察組收縮壓、舒張壓均較治療前明顯降低(P均0.05),且明顯低于對(duì)照組(P均0.05);觀察組TG水平顯著下降(P0.05),且顯著低于對(duì)照組(P0.05);觀察組Hb A1c與FPG均明顯改善(P均0.05),且明顯優(yōu)于對(duì)照組(P均0.05);觀察組總有效率明顯高于對(duì)照組(P0.05)。結(jié)論六君子湯合桃紅四物湯加味對(duì)于HUA效果確切,且能同時(shí)改善患者血壓、血糖、血脂以及體質(zhì)量指數(shù),并可避免應(yīng)用西藥帶來的不良反應(yīng),安全性高。
[Abstract]:Objective to investigate the clinical effect of Liujunzi decoction combined with Taohong Siwu decoction on hyperuricemia (HUA). Methods 60 patients with HUA were randomly divided into two groups: 30 patients in each group. All patients were treated with routine therapy. The observation group was treated with Liujunzi decoction and Taohong Siwu decoction on the basis of routine treatment. 12 weeks later, the blood pressure of serum uric acid (UA), was observed in both groups. The changes of (FPG), glycosylated hemoglobin (Hb A 1c) and body mass index (BMI) in triacylglycerol (TG), fasting blood glucose were evaluated. Results after treatment, the serum UA level in the control group had no significant change (P0.05), while the UA level in the observation group was significantly lower than that before the treatment (P0.05), and was significantly lower than that in the control group (P0.05). The systolic blood pressure and diastolic blood pressure in the observation group were significantly lower than those in the control group (P 0.05), and the levels of TG in the observation group were significantly lower than those in the control group (P0.05), and those in the observation group were significantly lower than those in the control group (P0.05). The Hb A1c and FPG of the observation group were improved significantly (P 0.05), and the total effective rate of the observation group was significantly higher than that of the control group (P0.05). Conclusion Liujunzi decoction combined with Taohong Siwu decoction can improve blood pressure, blood glucose, blood lipids and body mass index in patients with HUA.
【作者單位】： 北京市房山區(qū)中醫(yī)醫(yī)院;
【分類號(hào)】：R259

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