【摘要】：目的：評(píng)估安腦顆粒治療急性腦梗死痰瘀阻絡(luò)證的臨床療效,為安腦顆粒治療急性腦梗死提供依據(jù)。方法：嚴(yán)格選取60例2015年3月至2016年1月至江蘇省中西醫(yī)結(jié)合醫(yī)院就診的急性腦梗死患者辨證屬痰瘀阻絡(luò)證,將其隨機(jī)分為兩組：安腦顆粒組(治療組)和西藥組(對(duì)照組),每組各30名患者。治療組在對(duì)照組治療的基礎(chǔ)上加用安腦顆粒,每日1劑,早晚兩次溫服,兩組連續(xù)治療,療程14天。于治療前、治療后分別進(jìn)行中醫(yī)證候積分、NIHSS積分和Bathel評(píng)分,以此為依據(jù)評(píng)價(jià)安腦顆粒療效,同時(shí)在觀察過程中記錄安全性指標(biāo)及不良反應(yīng)。結(jié)果：1.經(jīng)統(tǒng)計(jì)檢驗(yàn),兩組患者在年齡、性別、治療前中醫(yī)證候積分、NIHSS評(píng)分及Bathel評(píng)分等方面比較均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),由此說明兩組病例具有可比性。2.治療14天后治療組和對(duì)照組兩組的中醫(yī)證候積分.NIHSS評(píng)分均有降低,Bathel評(píng)分均有升高,兩組治療前、治療后評(píng)分差異均具有高度統(tǒng)計(jì)學(xué)意義(P0.01)。3.將治療組及對(duì)照組治療后中醫(yī)證候積分.NIHSS評(píng)分及Bathel評(píng)分進(jìn)行統(tǒng)計(jì)學(xué)分析,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論：安腦顆粒治療急性腦梗死痰瘀阻絡(luò)證安全有效,可改善患者中醫(yī)證候及神經(jīng)功能缺損癥狀,提高患者自理能力,較單純西醫(yī)治療療效明顯,為安腦顆粒治療急性腦梗死提供依據(jù)。
[Abstract]:Objective: to evaluate the clinical efficacy of Annao granule in treating acute cerebral infarction with phlegm and blood stasis syndrome. Methods: from March 2015 to January 2016, 60 patients with acute cerebral infarction diagnosed as phlegm and stasis syndrome were randomly divided into two groups: group A (treatment group) and group B (control group). There were 30 patients in each group. In the treatment group, on the basis of the treatment in the control group, Annao granule was added, once a day, twice in the morning and evening, the two groups were treated continuously for 14 days. Before and after treatment, TCM syndromes score, NIHSS score and Bathel score were used to evaluate the efficacy of Annao granule. Meanwhile, safety indexes and adverse reactions were recorded in the course of observation. Results: 1. After statistical test, the two groups of patients in age, gender, TCM syndrome score before treatment, NIHSS score and Bathel score were not statistically significant (P0.05), which showed that the two groups of cases are comparable. 2. After 14 days of treatment, the scores of TCM syndromes, NIHSS scores and Bathel scores in the treatment group and the control group were all decreased, and the differences between the two groups before and after treatment were highly statistically significant (P0.01). The treatment group and control group after treatment of TCM syndrome score, NIHSS score and Bathel score were statistically analyzed, the difference was statistically significant (P0.05). Conclusion: Annao granule is safe and effective in treating phlegm and stagnation of collaterals in patients with acute cerebral infarction. It can improve the symptoms of TCM syndromes and nerve function defects, and improve the self-care ability of patients, which is more effective than that of western medicine alone. To provide evidence for the treatment of acute cerebral infarction with Annao granule.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R277.7

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