針?biāo)幗Y(jié)合干預(yù)痰濕質(zhì)代謝綜合征血脂異常患者的臨床研究
發(fā)布時(shí)間:2018-11-13 14:32
【摘要】:目的:本課題采用前瞻性隨機(jī)對照試驗(yàn),通過針?biāo)幗Y(jié)合治療與單純西藥治療作對照,評價(jià)治療前后患者體重、腰圍、中醫(yī)體質(zhì)積分、甘油三脂(TG)、總膽固醇(TC)、高密度脂蛋白膽固醇(HDL-C,High-density lipoprotein cholesterol)、低密度脂蛋白膽固醇(LDL-C,Low-density lipoprotein cholesterol)的變化差異,探討針?biāo)幗Y(jié)合干預(yù)痰濕質(zhì)代謝綜合征血脂異;颊叩呐R床療效,比較針?biāo)幗Y(jié)合治療與單純西藥對痰濕質(zhì)代謝綜合征血脂異;颊叩寞熜Р町,為尋求治療代謝綜合征更有效更理想的方法。方法:將2016年5月到2017年2月在佛山市中醫(yī)院治未病中心就診的患者,按照符合診斷標(biāo)準(zhǔn)、納入標(biāo)準(zhǔn)和排除標(biāo)準(zhǔn)的方法,收集痰濕質(zhì)代謝綜合征血脂異常病例60例,隨機(jī)分為治療組(針?biāo)幗Y(jié)合組)和對照組(單純西藥組)各30例。治療組在生活方式健康教育的基礎(chǔ)上,進(jìn)行耳穴、腹針結(jié)合山楂消脂膠囊的治療。治療組耳穴取穴:胃、脾、腹、內(nèi)分泌、神門、三焦穴。每次單側(cè)耳穴用管針針刺,另一側(cè)用耳穴壓丸法。腹針取穴:中脘、下腺、氣海、關(guān)元、雙側(cè)天樞、雙側(cè)大橫、雙側(cè)滑肉門、雙側(cè)外陵。對照組在生活方式健康教育的基礎(chǔ)上口服非諾貝特膠囊,每日晚餐服用1粒,每粒200mg。治療組與對照組均4周為1個(gè)療程,共治療2個(gè)療程;颊咝柙谥委熐昂炇鹬橥鈺,及中醫(yī)體質(zhì)量表,治療2個(gè)療程后再次填寫中醫(yī)體質(zhì)量表,復(fù)查體重、腰圍、TG、TC、HDL-C、LDL-C。結(jié)果:治療前對治療組與對照組進(jìn)行性別、年齡、體重、腰圍、中醫(yī)體質(zhì)積分、TG、TC、HDL-C、LDL-C的比較,差異沒有統(tǒng)計(jì)學(xué)意義(p≥0.05),兩組間具有可比性。治療2個(gè)療程后,兩組治療前與治療后的體重、腰圍、中醫(yī)體質(zhì)積分、TG、TC、HDL-C、LDL-C比較,差異均具有統(tǒng)計(jì)學(xué)意義(P0.05)。治療后兩組間在體重、TG、TC、HDL-C、LDL-C的比較上,差異沒有統(tǒng)計(jì)學(xué)意義(p≥0.05),而在腰圍及中醫(yī)體質(zhì)積分上,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:1.針?biāo)幗Y(jié)合組與單純西藥組治療痰濕質(zhì)代謝綜合征血脂異;颊呔携熜;2.針?biāo)幗Y(jié)合組對減輕痰濕質(zhì)代謝綜合征血脂異;颊叩捏w重,降低TG、TC、LDL-C,提高HDL-C的療效與單純西藥組的療效相當(dāng);3.針?biāo)幗Y(jié)合組對減小痰濕質(zhì)代謝綜合征血脂異;颊叩难鼑皽p小中醫(yī)體質(zhì)積分的療效優(yōu)于單純西藥組;4.耳穴、腹針結(jié)合山楂消脂膠囊是治療痰濕質(zhì)代謝綜合征血脂異;颊叩囊环N較理想的治療方法。
[Abstract]:Objective: to evaluate patients' body weight, waist circumference, TCM constitution integral and triglyceride (TG), total cholesterol (TC), before and after treatment by prospective randomized controlled trial. High density lipoprotein cholesterol (HDL-C,High-density lipoprotein cholesterol),) low density lipoprotein cholesterol (LDL-C,Low-density lipoprotein cholesterol) was studied in order to explore the clinical effect of acupuncture combined with medicine on hyperlipidemia in patients with phlegm-wet metabolic syndrome. To compare the curative effect of acupuncture and medicine combined therapy with western medicine on patients with dyslipidemia of phlegm-wet metabolic syndrome, and to seek a more effective and ideal method for the treatment of metabolic syndrome. Methods: from May 2016 to February 2017, 60 patients with dyslipidemia of phlegm-wet metabolic syndrome were collected according to the diagnostic criteria, inclusion criteria and exclusion criteria. They were randomly divided into treatment group (acupuncture combined group) and control group (simple western medicine group). Treatment group on the basis of lifestyle health education, auricular acupoints, abdominal acupuncture combined with Hawthorn Xiaozhi capsule treatment. Treatment group ear points: stomach, spleen, abdomen, endocrine, Shenmen, Sanjiao points. Each side of the auricular point was needled with a tube and the other side with the auricular acupoint pressing pill method. Ventral acupuncture points: Zhongwan, inferior gland, Qihai, Guanyuan, bilateral Tianshu, bilateral big transverse, bilateral sliding meat door, bilateral Wingling. The control group took fenofibrate capsule on the basis of lifestyle health education. Treatment group and control group were 4 weeks as a course of treatment, a total of 2 courses of treatment. Patients should sign informed consent form and TCM physique scale before treatment. After 2 courses of treatment, they should fill in TCM physique scale again, review body weight, waist circumference, TG,TC,HDL-C,LDL-C.. Results: there was no significant difference in sex, age, body weight, waist circumference, physique score and TG,TC,HDL-C,LDL-C between the two groups before treatment (p 鈮,
本文編號:2329446
[Abstract]:Objective: to evaluate patients' body weight, waist circumference, TCM constitution integral and triglyceride (TG), total cholesterol (TC), before and after treatment by prospective randomized controlled trial. High density lipoprotein cholesterol (HDL-C,High-density lipoprotein cholesterol),) low density lipoprotein cholesterol (LDL-C,Low-density lipoprotein cholesterol) was studied in order to explore the clinical effect of acupuncture combined with medicine on hyperlipidemia in patients with phlegm-wet metabolic syndrome. To compare the curative effect of acupuncture and medicine combined therapy with western medicine on patients with dyslipidemia of phlegm-wet metabolic syndrome, and to seek a more effective and ideal method for the treatment of metabolic syndrome. Methods: from May 2016 to February 2017, 60 patients with dyslipidemia of phlegm-wet metabolic syndrome were collected according to the diagnostic criteria, inclusion criteria and exclusion criteria. They were randomly divided into treatment group (acupuncture combined group) and control group (simple western medicine group). Treatment group on the basis of lifestyle health education, auricular acupoints, abdominal acupuncture combined with Hawthorn Xiaozhi capsule treatment. Treatment group ear points: stomach, spleen, abdomen, endocrine, Shenmen, Sanjiao points. Each side of the auricular point was needled with a tube and the other side with the auricular acupoint pressing pill method. Ventral acupuncture points: Zhongwan, inferior gland, Qihai, Guanyuan, bilateral Tianshu, bilateral big transverse, bilateral sliding meat door, bilateral Wingling. The control group took fenofibrate capsule on the basis of lifestyle health education. Treatment group and control group were 4 weeks as a course of treatment, a total of 2 courses of treatment. Patients should sign informed consent form and TCM physique scale before treatment. After 2 courses of treatment, they should fill in TCM physique scale again, review body weight, waist circumference, TG,TC,HDL-C,LDL-C.. Results: there was no significant difference in sex, age, body weight, waist circumference, physique score and TG,TC,HDL-C,LDL-C between the two groups before treatment (p 鈮,
本文編號:2329446
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