自擬平肝養(yǎng)血湯治療偏頭痛肝陽上亢證的臨床觀察
發(fā)布時間：2018-11-11 15:26
【摘要】：研究目的:本研究課題是基于通過對近些年來偏頭痛肝陽上亢證的中醫(yī)辨證論治觀察及偏頭痛肝陽上亢證的治療進行調查、分析、思考后,針對當今中西醫(yī)治療上的成果及出現(xiàn)的問題進行分析思考與總結。最終擬定平肝養(yǎng)血湯,對臨床上出現(xiàn)的偏頭痛肝陽上亢證患者的證候指征評分作為觀察與統(tǒng)計的指標、以中醫(yī)辨證論治為方法的觀察與研究,探討并初步制定一套更為規(guī)范化的臨床治療方案,觀察中藥治療偏頭痛肝陽上亢證的療效,從而探討新的治療偏頭痛肝陽上亢證的規(guī)范化中醫(yī)診療方案。研究方法:選取72例在長春中醫(yī)藥大學附屬醫(yī)院老年病一科門診或療區(qū)就診的符合本研究納入標準的偏頭痛患者,隨機分為治療組36例,對照組36例,病例采集日期為2013年12月至2015年12月。治療組給予閆鳳杰教授的經驗方平肝養(yǎng)血湯;對照組給予天士力制藥集團股份有限公司養(yǎng)血清腦顆粒(國藥準字Z10960082)口服。兩組療程相同,均為4周。分別觀察兩組患者的疼痛評分變化和中醫(yī)證侯積分、病程、年齡等進行統(tǒng)計分析。分別觀察治療期間的藥物療效性和安全性。研究結果:(1)治療組與對照組臨床療效的總有效率分別為88.89%和66.67%。治療組與對照組的總療效有明顯差異(P0.05),說明治療組平肝養(yǎng)血湯的療效優(yōu)于對照組養(yǎng)血清腦顆粒。(2)兩組患者治療后的中醫(yī)證侯總積分對比治療前均有明顯下降,同時兩組患者治療后的組間比較有明顯差異(P0.05),說明平肝養(yǎng)血湯和養(yǎng)血清腦顆粒兩種藥物均能有效緩解頭痛,改善中醫(yī)癥候,同時治療組平肝養(yǎng)血湯在緩解頭痛以及改善中醫(yī)癥候方面均優(yōu)于養(yǎng)血清腦顆粒。結論:在臨床上兩種藥物取均有較好療效,經過研究結果分析后發(fā)現(xiàn)治療組在臨床癥狀的改善等方面要優(yōu)于對照組,服藥過程中患者安全性指標均未見異常,說明平肝養(yǎng)血湯有確切療效又安全可靠,具有一定的臨床推廣價值。
[Abstract]:Objective: this research subject is based on the observation of TCM syndrome differentiation and treatment of migraine liver yang hyperactivity syndrome in recent years and the treatment of migraine liver yang hyperactivity syndrome. This paper analyzes and summarizes the achievements and problems in the treatment of traditional Chinese and western medicine. Finally, we draw up Pinggan Yangxue decoction, and observe and study the syndrome indication score of the patients with syndrome of migraine and liver yang hyperactivity in clinic as the index of observation and statistics, and take TCM syndrome differentiation and treatment as the method of observation and research. To explore and preliminarily establish a more standardized clinical treatment plan, observe the efficacy of Chinese medicine in treating migraine and liver yang hyperactivity syndrome, and explore a new standardized Chinese medicine diagnosis and treatment scheme for migraine liver yang hyperactivity syndrome. Methods: a total of 72 patients with migraine, who met the criteria of this study, were randomly divided into treatment group (n = 36) and control group (n = 36). Cases were collected from December 2013 to December 2015. The treatment group was given Professor Yan Fengjie's experience Fang Pinggan Yangxue decoction and the control group was given Yangxuannao granule (Z10960082) of Tianshili Pharmaceutical Group Co., Ltd. The course of treatment was the same in both groups (4 weeks). The changes of pain score, TCM syndromes score, course of disease, age and so on were observed. The efficacy and safety of the drug during the treatment were observed. Results: (1) the total effective rates of the treatment group and the control group were 88.89% and 66.67% respectively. There was significant difference between the treatment group and the control group in the total curative effect (P0.05), indicating that the therapeutic effect of the treatment group was better than that of the control group. (2) after treatment, the total score of traditional Chinese medicine syndrome in the two groups were significantly decreased before treatment. At the same time, there was a significant difference between the two groups after treatment (P0.05), indicating that Pinggan Yangxue decoction and Yangxuannao granule can effectively relieve headache and improve TCM symptoms. At the same time, the treatment group was superior to Yangxuannao granule in relieving headache and improving symptoms of TCM. Conclusion: the two drugs have good curative effect in clinic. After the analysis of the results, it is found that the treatment group is superior to the control group in the improvement of clinical symptoms, and the safety indexes of the patients in the course of taking medicine are not abnormal. It shows that Pinggan Yangxue decoction has definite curative effect, safe and reliable, and has certain clinical popularizing value.
【學位授予單位】：長春中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R277.7
本文編號：2325271
[Abstract]:Objective: this research subject is based on the observation of TCM syndrome differentiation and treatment of migraine liver yang hyperactivity syndrome in recent years and the treatment of migraine liver yang hyperactivity syndrome. This paper analyzes and summarizes the achievements and problems in the treatment of traditional Chinese and western medicine. Finally, we draw up Pinggan Yangxue decoction, and observe and study the syndrome indication score of the patients with syndrome of migraine and liver yang hyperactivity in clinic as the index of observation and statistics, and take TCM syndrome differentiation and treatment as the method of observation and research. To explore and preliminarily establish a more standardized clinical treatment plan, observe the efficacy of Chinese medicine in treating migraine and liver yang hyperactivity syndrome, and explore a new standardized Chinese medicine diagnosis and treatment scheme for migraine liver yang hyperactivity syndrome. Methods: a total of 72 patients with migraine, who met the criteria of this study, were randomly divided into treatment group (n = 36) and control group (n = 36). Cases were collected from December 2013 to December 2015. The treatment group was given Professor Yan Fengjie's experience Fang Pinggan Yangxue decoction and the control group was given Yangxuannao granule (Z10960082) of Tianshili Pharmaceutical Group Co., Ltd. The course of treatment was the same in both groups (4 weeks). The changes of pain score, TCM syndromes score, course of disease, age and so on were observed. The efficacy and safety of the drug during the treatment were observed. Results: (1) the total effective rates of the treatment group and the control group were 88.89% and 66.67% respectively. There was significant difference between the treatment group and the control group in the total curative effect (P0.05), indicating that the therapeutic effect of the treatment group was better than that of the control group. (2) after treatment, the total score of traditional Chinese medicine syndrome in the two groups were significantly decreased before treatment. At the same time, there was a significant difference between the two groups after treatment (P0.05), indicating that Pinggan Yangxue decoction and Yangxuannao granule can effectively relieve headache and improve TCM symptoms. At the same time, the treatment group was superior to Yangxuannao granule in relieving headache and improving symptoms of TCM. Conclusion: the two drugs have good curative effect in clinic. After the analysis of the results, it is found that the treatment group is superior to the control group in the improvement of clinical symptoms, and the safety indexes of the patients in the course of taking medicine are not abnormal. It shows that Pinggan Yangxue decoction has definite curative effect, safe and reliable, and has certain clinical popularizing value.
【學位授予單位】：長春中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R277.7
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