【摘要】：目的:觀察膝骨關(guān)節(jié)炎在小針刀配合補腎強筋膠囊療法治療下的療效,為臨床治療膝骨關(guān)節(jié)炎提供新的方向,以提高臨床療效為目的,為進一步規(guī)范化膝骨關(guān)節(jié)炎的臨床研究提供思路;并在治療前后進行紅外熱成像檢查,與評價療效的相關(guān)評分進行分析,以期挖掘一項客觀指標(biāo)運用于膝骨關(guān)節(jié)炎臨床效評估。方法:根據(jù)病例納入標(biāo)準(zhǔn)及病例排除標(biāo)準(zhǔn),于2016年1月至2017年1月共收集90例患者,所有患者臨床上已經(jīng)確診為腎虛血瘀型膝骨關(guān)節(jié)炎,隨機分為試驗Ⅰ組30例(小針刀配合補腎強筋膠囊)、試驗Ⅱ組30例(補腎強筋膠囊口服)及對照組30例(塞來昔布膠囊口服)。記錄并統(tǒng)計分析各組治療前后的觀察指標(biāo)包括WOMAC評分、VAS評分以及紅外熱成像圖譜溫度值。結(jié)果:臨床療效:試驗Ⅰ組、試驗Ⅱ組與對照組的總有效率分別為96.7%、90.0%、93.3%,試驗Ⅰ組臨床療效優(yōu)于試驗Ⅱ組與對照組(P0.05),試驗Ⅱ組與對照組無顯著性差異(P)0.05)。WOMAC評分:治療前三組間WOMAC評分無顯著性差異(P0.05);治療后三組間WOMAC評分有顯著性差異(P0.01);三組WOMAC評分治療前后對比均有顯著性差異(P0.01);三組間WOMAC評分差值有顯著性差異(P0.01),與試驗Ⅰ組對比,試驗Ⅱ組、對照組的WOMAC評分差值有顯著性差異(P0.05);與試驗Ⅱ組對比,對照組的WOMAC評分差值無顯著性差異(P0.05)。在改善WOMAC評分方面,試驗Ⅰ組優(yōu)于試驗Ⅱ組與對照組,試驗Ⅱ組與對照組療效相當(dāng)。VAS評分:治療前三組間VAS評分無顯著性差異(P0.05);治療后三組間VAS評分有顯著性差異(P0.01);三組VAS評分治療前后對比均有顯著性差異(P0.01);三組間VAS評分差值有顯著性差異(P0.01),與試驗Ⅰ組對比,試驗Ⅱ組、對照組的VAS評分差值有顯著性差異(P0.01);與試驗Ⅱ組對比,對照組的VAS評分差值有顯著性差異(P0.05)。在改善VAS評分方面,試驗Ⅰ組優(yōu)于對照組,對照組優(yōu)于試驗Ⅱ組。熱成像溫度值:治療前三組紅外熱成像圖譜的溫度值無顯著性差異(P0.05);三組溫度治療前后對比均有顯著性差異(P0.01);治療后三組溫度值有顯著性差異(P0.01),與試驗Ⅰ組對比,試驗Ⅱ組無顯著性差異(P0.05)、對照組有顯著性差異(P0.05);與試驗Ⅱ組對比,對照組無顯著性差異(P0.05)。經(jīng)治療后三組溫度值均有下降趨勢。不良事件:治療期間,試驗Ⅰ組與試驗Ⅱ組分別出現(xiàn)出現(xiàn)咽干口苦不適各1例,對照組出現(xiàn)胃腸道不適1例,三組不良事件發(fā)生率均為1/30。結(jié)論:1.膝骨關(guān)節(jié)炎通過小針刀配合補腎強筋膠囊治療能改善關(guān)節(jié)功能、緩解疼痛。2.在膝骨關(guān)節(jié)炎治療過程中小針刀與補腎強筋膠囊具有協(xié)同作用。3.紅外熱成像技術(shù)運用于膝骨關(guān)節(jié)炎臨床療效評估是可行的。
[Abstract]:Objective: to observe the curative effect of knee osteoarthritis treated by small needle knife and Bushen Qiangjin capsule, and to provide a new direction for clinical treatment of knee osteoarthritis, in order to improve the clinical curative effect. To further standardize the clinical study of knee osteoarthritis. Infrared thermal imaging was performed before and after treatment, and related scores for evaluation of curative effect were analyzed in order to excavate an objective index to evaluate the clinical efficacy of knee osteoarthritis. Methods: a total of 90 patients were collected from January 2016 to January 2017 according to the criteria of inclusion and exclusion of cases, all of whom had been clinically diagnosed as knee osteoarthritis with kidney deficiency and blood stasis. They were randomly divided into trial group 鈪，

本文編號：2319703