冬病夏治治療膝骨關(guān)節(jié)炎陽(yáng)虛寒凝證的臨床療效觀察
發(fā)布時(shí)間：2018-11-08 20:56
【摘要】：目的:觀察冬病夏治治療膝骨關(guān)節(jié)炎陽(yáng)虛寒凝證的臨床療效,為臨床治療膝骨關(guān)節(jié)炎提供另外一種思路與方法。方法:選擇湖南中醫(yī)藥大學(xué)第一附屬醫(yī)院骨傷科門診在2015年1月至2015年7月期間就診的患者,符合膝骨關(guān)節(jié)炎診斷,中醫(yī)辨證為陽(yáng)虛寒凝證,累積80例。按隨機(jī)數(shù)字表法將80例患者膝骨關(guān)節(jié)炎(陽(yáng)虛寒凝證)患者隨機(jī)分為兩組,對(duì)照組40例患者口服硫酸氨基葡萄糖膠囊(每日3次,每次2粒),口服雙醋瑞因膠囊(4周前,每日1粒,晚餐后口服,后每日2次,每次1粒,飯后口服),治療組口服硫酸氨基葡萄糖膠囊(每日3次,每次2粒),口服雙醋瑞因膠囊(4周前,每日1粒,晚餐后口服,后每日2次,每次1粒,飯后口服)配合三伏天穴位貼敷治療;兩組口服藥物的治療時(shí)間均為3個(gè)月。治療結(jié)束后,觀察兩組患者治療前與治療后、冬天三九天的VAS評(píng)分、WOMAC評(píng)分及中醫(yī)療效評(píng)價(jià)。結(jié)果:1.組內(nèi)比較:治療后,對(duì)照組與治療組兩組患者的VAS評(píng)分、WOMAC評(píng)分較治療前得分均有降低,兩組患者與治療前比較均有差異,差異有顯著和非常顯著的統(tǒng)計(jì)學(xué)意義((P0.05,P0.01);一九天對(duì)照組與治療組兩組患者的VAS評(píng)分、WOMAC評(píng)分得分較治療前得分有降低,與治療前比較,兩者得分有顯著統(tǒng)計(jì)學(xué)意義(P0.05);二九天與三九天對(duì)照組VAS評(píng)分、WOMAC評(píng)分得分較治療前得分有所降低,但與治療前比較無(wú)差異,無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),治療組VAS評(píng)分、WOMAC評(píng)分得分較治療前得分有降低,與治療前比較,兩者得分均有統(tǒng)計(jì)學(xué)意義(P0.05);2.組間比較:治療后及一九天兩個(gè)時(shí)間段,對(duì)照組與治療組在VAS評(píng)分、WOMAC評(píng)分及中醫(yī)療效方面比較,無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);在二九天、三九天兩個(gè)時(shí)間段,對(duì)照組與治療組在VAS評(píng)分、WOMAC評(píng)分及中醫(yī)療效方面比較有顯著統(tǒng)計(jì)學(xué)意義(P0.05)和非常顯著的統(tǒng)計(jì)學(xué)意義(P0.01)。結(jié)論:1.冬病夏治法較單純口服藥物治療更能改善膝骨關(guān)節(jié)炎陽(yáng)虛寒凝證在三九天的疼痛情況。2.冬病夏治法較單純口服藥物治療能明顯降低膝骨關(guān)節(jié)炎陽(yáng)虛寒凝證在三九天的WOMAC評(píng)分。3.冬病夏治法較單純口服藥物治療能明顯減少膝骨關(guān)節(jié)炎陽(yáng)虛寒凝證在三九天的發(fā)病次數(shù)。4.冬病夏治法較單純口服藥物治療能明顯減少膝骨關(guān)節(jié)炎陽(yáng)虛寒凝證在三九天的畏寒、遇寒痛增情況。
[Abstract]:Objective: to observe the clinical effect of treating knee osteoarthritis with yang deficiency and cold coagulation in the treatment of winter disease and summer, and to provide another way of thinking and method for clinical treatment of knee osteoarthritis. Methods: the patients in Department of Orthopaedics and Trauma of the first affiliated Hospital of Hunan University of traditional Chinese Medicine from January 2015 to July 2015 were selected and diagnosed according to the diagnosis of knee osteoarthritis. 80 patients with knee osteoarthritis (Yang deficiency and cold coagulation syndrome) were randomly divided into two groups: the control group (40 cases) received glucosamine sulfate capsules (2 capsules per day 3 times a day) and diacetate capsules (4 weeks ago). The treatment group was treated with glucosamine sulfate capsules (2 capsules per day, 3 times a day) and diacetate capsules (1 capsule per day, 4 weeks ago). After dinner oral, after 2 times a day, each time, oral after meals) with three days of acupoint application treatment; The treatment time of oral drugs in both groups was 3 months. After treatment, the VAS score, WOMAC score and TCM curative effect were observed before and after treatment. The result is 1: 1. Intra-group comparison: after treatment, the VAS scores and WOMAC scores of patients in the control group and the treatment group were lower than those before treatment, and there were significant and very significant differences between the two groups (P 0.05, P 0.05). P0.01); The VAS score and WOMAC score of the control group and the treatment group were significantly lower than those before treatment (P0.05). The scores of VAS and WOMAC in the control group were lower than those before treatment, but there was no significant difference between before and after treatment (P0.05). The VAS score and WOMAC score of the treatment group were lower than those before treatment. Compared with before treatment, both scores were statistically significant (P0.05); 2. Comparison between groups: after treatment and 19 days, the control group and the treatment group in VAS score, WOMAC score and TCM efficacy comparison, there was no statistical significance (P0.05); In two periods of 29 days, 39 days, the control group and the treatment group in VAS score, WOMAC score and curative effect of traditional Chinese medicine compared with significant statistical significance (P0.05) and very significant statistical significance (P0.01). Conclusion: 1. The treatment of winter disease and summer can improve the pain of knee osteoarthritis with yang deficiency and cold coagulation in 39 days. 2. The treatment of winter disease and summer can obviously reduce the WOMAC score of knee osteoarthritis with yang deficiency and cold coagulation in 39 days. The treatment of winter disease and summer treatment can obviously reduce the incidence times of yang deficiency and cold coagulation syndrome of knee osteoarthritis in 39 days. 4. The treatment of winter disease and summer treatment was more effective than oral medicine only in reducing the chills and increasing cold pain in knee osteoarthritis with Yang deficiency and cold coagulation syndrome in three or nine days.
【學(xué)位授予單位】：湖南中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R274.9
[Abstract]:Objective: to observe the clinical effect of treating knee osteoarthritis with yang deficiency and cold coagulation in the treatment of winter disease and summer, and to provide another way of thinking and method for clinical treatment of knee osteoarthritis. Methods: the patients in Department of Orthopaedics and Trauma of the first affiliated Hospital of Hunan University of traditional Chinese Medicine from January 2015 to July 2015 were selected and diagnosed according to the diagnosis of knee osteoarthritis. 80 patients with knee osteoarthritis (Yang deficiency and cold coagulation syndrome) were randomly divided into two groups: the control group (40 cases) received glucosamine sulfate capsules (2 capsules per day 3 times a day) and diacetate capsules (4 weeks ago). The treatment group was treated with glucosamine sulfate capsules (2 capsules per day, 3 times a day) and diacetate capsules (1 capsule per day, 4 weeks ago). After dinner oral, after 2 times a day, each time, oral after meals) with three days of acupoint application treatment; The treatment time of oral drugs in both groups was 3 months. After treatment, the VAS score, WOMAC score and TCM curative effect were observed before and after treatment. The result is 1: 1. Intra-group comparison: after treatment, the VAS scores and WOMAC scores of patients in the control group and the treatment group were lower than those before treatment, and there were significant and very significant differences between the two groups (P 0.05, P 0.05). P0.01); The VAS score and WOMAC score of the control group and the treatment group were significantly lower than those before treatment (P0.05). The scores of VAS and WOMAC in the control group were lower than those before treatment, but there was no significant difference between before and after treatment (P0.05). The VAS score and WOMAC score of the treatment group were lower than those before treatment. Compared with before treatment, both scores were statistically significant (P0.05); 2. Comparison between groups: after treatment and 19 days, the control group and the treatment group in VAS score, WOMAC score and TCM efficacy comparison, there was no statistical significance (P0.05); In two periods of 29 days, 39 days, the control group and the treatment group in VAS score, WOMAC score and curative effect of traditional Chinese medicine compared with significant statistical significance (P0.05) and very significant statistical significance (P0.01). Conclusion: 1. The treatment of winter disease and summer can improve the pain of knee osteoarthritis with yang deficiency and cold coagulation in 39 days. 2. The treatment of winter disease and summer can obviously reduce the WOMAC score of knee osteoarthritis with yang deficiency and cold coagulation in 39 days. The treatment of winter disease and summer treatment can obviously reduce the incidence times of yang deficiency and cold coagulation syndrome of knee osteoarthritis in 39 days. 4. The treatment of winter disease and summer treatment was more effective than oral medicine only in reducing the chills and increasing cold pain in knee osteoarthritis with Yang deficiency and cold coagulation syndrome in three or nine days.
【學(xué)位授予單位】：湖南中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R274.9
【參考文獻(xiàn)】
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