代赭旋覆湯治療痰氣交阻型胃食管反流病的臨床研究
發(fā)布時(shí)間：2018-11-07 16:56
【摘要】：胃食管逆流疾病(Gastroesophageal reflux disease,GERD)其定義是指患者因胃內(nèi)容物不正常逆流至食管所形成的。其中以心灼熱感和胃酸逆流為最常見的癥狀。雖然西方國家盛行率比東方國家高,但在內(nèi)地及臺(tái)灣,胃食管逆流疾病的族群有逐年增加的趨勢(shì),不但對(duì)病患造成生活的困擾及生活質(zhì)量的影響,也因此減低工作生產(chǎn)力,消耗診斷及治療的醫(yī)療資源也極為可觀。目的：本研究旨在觀察臺(tái)灣地區(qū)使用代赭旋覆湯科學(xué)中藥粉治療痰氣交阻證胃食管反流病的臨床療效,并比較針刺治療與藥物治療的效果。方法：收集就診于臺(tái)灣國烈中醫(yī)診所之痰氣交阻證胃食管反流病患者60例,全部符合胃食管反流病臨床診斷,按照隨機(jī)分組方法將患者分為觀察組和對(duì)照組,每組各30例。觀察組給予代赭旋覆湯科學(xué)中藥粉加減,中藥粉每日三服,每次一包,每周復(fù)診一次；對(duì)照組給予針刺治療,選穴足三里、中脘、內(nèi)關(guān)、梁門、天樞、四神聰、神庭每周2次,留針30分鐘,全部療程為8周。于治療前、治療8周填寫量表。統(tǒng)計(jì)分析方法：使用SPSS19.0軟件對(duì)所有數(shù)據(jù)進(jìn)行比較分析。采用x2檢驗(yàn)分析計(jì)數(shù)資料,采用t檢驗(yàn)分析計(jì)量資料,采用秩和檢驗(yàn)分析等量資料。結(jié)果：于臺(tái)灣國烈中醫(yī)診所共收集60例符合痰氣交阻證胃食管反流病患者,分為觀察組及對(duì)照組,各30例。兩組間性別、年齡、病勢(shì)的差異均不具統(tǒng)計(jì)學(xué)意義(P0.05),表示觀查組與對(duì)照組具可比性。觀查組與對(duì)照組之GerdQ量表、中醫(yī)癥狀積分量表積分顯示,兩組各自之治療后總積分低于治療前總積分,其差異具統(tǒng)計(jì)學(xué)意義。觀查組與對(duì)照組的治療后積分,經(jīng)獨(dú)立樣本t檢驗(yàn)分析,P0.05,具統(tǒng)計(jì)學(xué)意義。分析中醫(yī)癥狀積分量表治療前后之主證與次證積分,觀察組67%的癥狀具統(tǒng)計(jì)學(xué)意義,對(duì)照組78%的癥狀具統(tǒng)計(jì)學(xué)意義。結(jié)論：GerdQ量表及中醫(yī)癥狀積分量表積分均顯示,觀查組與對(duì)照組治療后癥狀皆獲得改善,且觀察組優(yōu)于對(duì)照組。表示代赭旋覆湯科學(xué)中藥粉治療胃食管反流病的療效優(yōu)于單純針刺治療。觀察組治療較具證狀針對(duì)性,改善各癥狀效果較突出；對(duì)照組具廣泛性,普遍減輕各項(xiàng)證狀,但單一效用較弱。
[Abstract]:Gastroesophageal reflux disease (Gastroesophageal reflux disease,GERD) is defined as the formation of abnormal reflux of stomach contents to the esophagus. Heartburn and acid reflux are the most common symptoms. Although the prevalence rate in the western countries is higher than that in the eastern countries, in the mainland and Taiwan, the number of people suffering from gastroesophageal reflux disease is increasing year by year, which not only affects the patients' lives and the quality of life, but also reduces the productivity of work. Medical resources for diagnosis and treatment are also very significant. Objective: to observe the clinical effect of treating gastroesophageal reflux disease of syndrome of phlegm and qi obstruction with daizhuanfu decoction in Taiwan, and to compare the effect of acupuncture and drug therapy. Methods: sixty patients with gastroesophageal reflux disease with phlegm and qi obstruction syndrome were collected and divided into observation group (n = 30) and control group (n = 30) according to the clinical diagnosis of gastroesophageal reflux disease (GERD). The observation group was given daizhe Xianfu decoction scientific Chinese medicine powder added or subtracted, three times a day, one packet each time, every week; The control group was treated with acupuncture. Zusanli, Zhongwan, Neiguan, Liang Men, Tianshu, Sishencong, Shenting were treated twice a week with 30 minutes of needle retention for 8 weeks. Before treatment, fill out the scale for 8 weeks. Statistical analysis method: using SPSS19.0 software to compare and analyze all the data. The counting data were analyzed by x2 test, the measurement data were analyzed by t test, and the equivalent data were analyzed by rank sum test. Results: a total of 60 patients with gastroesophageal reflux according to phlegm and qi syndrome were collected in Taiwan Guolie TCM Clinic. They were divided into observation group and control group, 30 cases in each group. There was no significant difference in sex, age and disease potential between the two groups (P0.05), indicating that the observation group was comparable with the control group. The GerdQ scale and TCM symptom scale integral showed that the total score of the two groups after treatment was lower than that before treatment, and the difference was statistically significant. After treatment, the scores of observation group and control group were statistically significant by t test analysis (P 0.05). Before and after treatment, 67% of the symptoms in the observation group were statistically significant, and 78% of the symptoms in the control group were statistically significant. Conclusion: both the GerdQ scale and the integral scale of TCM symptom scale showed that the symptoms of the observation group and the control group were improved after treatment, and the observation group was superior to the control group. The therapeutic effect of traditional Chinese medicine powder in treating gastroesophageal reflux disease is better than that of acupuncture alone. In the observation group, the treatment was more targeted, and the effect of improving the symptoms was more prominent. In the control group, the symptoms were generalized and the symptoms were generally alleviated, but the single effect was weak.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259
[Abstract]:Gastroesophageal reflux disease (Gastroesophageal reflux disease,GERD) is defined as the formation of abnormal reflux of stomach contents to the esophagus. Heartburn and acid reflux are the most common symptoms. Although the prevalence rate in the western countries is higher than that in the eastern countries, in the mainland and Taiwan, the number of people suffering from gastroesophageal reflux disease is increasing year by year, which not only affects the patients' lives and the quality of life, but also reduces the productivity of work. Medical resources for diagnosis and treatment are also very significant. Objective: to observe the clinical effect of treating gastroesophageal reflux disease of syndrome of phlegm and qi obstruction with daizhuanfu decoction in Taiwan, and to compare the effect of acupuncture and drug therapy. Methods: sixty patients with gastroesophageal reflux disease with phlegm and qi obstruction syndrome were collected and divided into observation group (n = 30) and control group (n = 30) according to the clinical diagnosis of gastroesophageal reflux disease (GERD). The observation group was given daizhe Xianfu decoction scientific Chinese medicine powder added or subtracted, three times a day, one packet each time, every week; The control group was treated with acupuncture. Zusanli, Zhongwan, Neiguan, Liang Men, Tianshu, Sishencong, Shenting were treated twice a week with 30 minutes of needle retention for 8 weeks. Before treatment, fill out the scale for 8 weeks. Statistical analysis method: using SPSS19.0 software to compare and analyze all the data. The counting data were analyzed by x2 test, the measurement data were analyzed by t test, and the equivalent data were analyzed by rank sum test. Results: a total of 60 patients with gastroesophageal reflux according to phlegm and qi syndrome were collected in Taiwan Guolie TCM Clinic. They were divided into observation group and control group, 30 cases in each group. There was no significant difference in sex, age and disease potential between the two groups (P0.05), indicating that the observation group was comparable with the control group. The GerdQ scale and TCM symptom scale integral showed that the total score of the two groups after treatment was lower than that before treatment, and the difference was statistically significant. After treatment, the scores of observation group and control group were statistically significant by t test analysis (P 0.05). Before and after treatment, 67% of the symptoms in the observation group were statistically significant, and 78% of the symptoms in the control group were statistically significant. Conclusion: both the GerdQ scale and the integral scale of TCM symptom scale showed that the symptoms of the observation group and the control group were improved after treatment, and the observation group was superior to the control group. The therapeutic effect of traditional Chinese medicine powder in treating gastroesophageal reflux disease is better than that of acupuncture alone. In the observation group, the treatment was more targeted, and the effect of improving the symptoms was more prominent. In the control group, the symptoms were generalized and the symptoms were generally alleviated, but the single effect was weak.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R259
【參考文獻(xiàn)】
相關(guān)期刊論文 前5條
1 黃琳;;腹針配合中藥治療胃食管反流病的療效觀察[J];湖北中醫(yī)雜志;2012年02期
2 杜艷茹;劉啟泉;王淑杰;齊媛;;英連降胃湯治療反流性食管炎126例臨床研究[J];河北中醫(yī)藥學(xué)報(bào);2008年03期
3 林三仁;許國銘;胡品津;周麗雅;陳e，
本文編號(hào)：2316976
本文鏈接：http://sikaile.net/zhongyixuelunwen/2316976.html
最近更新
教材專著
