【摘要】：目的：觀察針刺和口服西藥治療心臟神經(jīng)官能癥的臨床療效,并比較兩種方法療效之間的差異,進一步明確針刺治療心臟神經(jīng)官能癥的臨床療效。方法：本研究將符合納入標準的130例患者,隨機分成兩組即治療組(針刺組)和對照組(口服西藥組),每組各65例。觀察入組治療前后及隨訪時兩組受試者的漢密爾頓焦慮量表評分(HAMA)、焦慮程度、軀體化癥狀自評量表評分(SSS)、癥狀積分表評分的變化,比較兩組組間及組內(nèi)差異。結(jié)果：1.基線：治療前兩組資料基線一致,P0.05,具有可比性。2.漢密爾頓焦慮量表評分(HAMA)及焦慮等級：(1)組間比較：治療后及隨訪時針刺組和口服西藥組HAMA評分及焦慮等級比較,其差異均具有統(tǒng)計學意義(P0.05)。(2)組內(nèi)比較：針刺組和口服西藥組在治療前后HAMA評分及焦慮等級比較,其差異具有統(tǒng)計學意義(P0.05)；隨訪時兩組HAMA評分與治療后相比,差異具有統(tǒng)計學意義(P0.05)。3.軀體化癥狀自評量表評分(SSS)：(1)組間比較：針刺組和口服西藥組在治療后的SSS評分比較,差異有統(tǒng)計學意義(P0.05)；兩組在隨訪時SSS評分比較,差異無統(tǒng)計學意義(P0.05)(2)組內(nèi)比較：針刺組及口服西藥組治療前后SSS評分比較,其差異均有統(tǒng)計學意義(P0.05)：隨訪時兩組SSS評分與治療后相比,差異有統(tǒng)計學意義(P0.05)。4.癥狀積分：(1)組間比較：針刺組和口服西藥組治療后及隨訪時的癥狀積分比較,差異均有統(tǒng)計學意義(P0.05)。 (2)組內(nèi)比較：針刺組及口服西藥組在治療前后癥狀積分比較,其差異均有統(tǒng)計學意義(P0.05)；隨訪時癥狀積分與治療后相比,差異有統(tǒng)計學意義(P0.05)。5.總有效率：治療結(jié)束后,針刺組總有效率86.88%,口服西藥組總有效率71.43%。6.兩組依次性、安全性均較好。結(jié)論：1.針刺與口服西藥對心臟神經(jīng)宮能癥癥狀均具有不同程度的改善作用,且兩種治療方法均有效,但針刺治療的臨床療效優(yōu)于口服西藥。2.針刺治療心臟神經(jīng)官能癥在改善患者焦慮情況和軀體化癥狀方面優(yōu)于口服西藥。針刺改善心臟神經(jīng)官能癥患者焦慮情況遠期療效優(yōu)于口服西藥。3.本試驗中兩組治療方法的安全性、依從性均較好,且針刺療法是治療心臟神經(jīng)官能癥的一種安全有效的治療方法,值得臨床進一步推廣和發(fā)揚。
[Abstract]:Objective: to observe the clinical efficacy of acupuncture and oral western medicine in the treatment of cardiac neurosis and compare the difference between the two methods. Methods: 130 patients were randomly divided into two groups: treatment group (acupuncture group) and control group (oral western medicine group) with 65 cases in each group. Hamilton anxiety scale (HAMA),) and somatization symptom Checklist (SSS),) were observed before and after treatment, and the differences between the two groups were compared. The result is 1: 1. Baseline: the baseline of the two groups before treatment was consistent (P 0.05) and comparable. Hamilton anxiety scale score (HAMA) and anxiety rating: (1) comparison between groups: after treatment and follow-up, HAMA score and anxiety grade were compared between acupuncture group and oral western medicine group. The differences were statistically significant (P0.05). (2) within the group: acupuncture group and oral western medicine group before and after treatment of HAMA score and anxiety grade comparison, the difference was statistically significant (P0.05); follow up between the two groups compared with after treatment HAMA score, The difference was statistically significant (P0.05). Somatization symptom Checklist score (SSS): (1): there was significant difference in SSS score between acupuncture group and oral western medicine group after treatment (P0.05). No significant difference (P0.05) (2) intragroup comparison: acupuncture group and oral western medicine group before and after treatment of SSS scores, the differences were statistically significant (P0.05): at the follow-up of the two groups compared with the treatment, the difference was statistically significant (P0.05). 4. Symptom score: (1) comparison between groups: acupuncture group and oral western medicine group after treatment and follow up the symptom score comparison, the difference was statistically significant (P0.05). (2) Intra-group comparison: the symptoms of acupuncture group and oral western medicine group before and after treatment, the differences were statistically significant (P0.05); at follow-up compared with the treatment, the difference was statistically significant (P0.05). Total effective rate: after treatment, the total effective rate of acupuncture group was 86.88 and that of oral western medicine group was 71.43.6. The safety of the two groups was better than that of the control group. Conclusion 1. Both acupuncture and oral western medicine can improve the symptoms of cardiac neurohypersensitivity in different degrees, and both of them are effective, but the clinical effect of acupuncture is better than that of oral western medicine. 2. Acupuncture is superior to oral medicine in improving anxiety and somatization of patients with cardiac neurosis. The long-term effect of acupuncture on anxiety of patients with cardiac neurosis is better than that of oral medicine. 3. In this experiment, the safety and compliance of the two treatment methods are good, and acupuncture therapy is a safe and effective method for the treatment of cardiac neurosis, which is worthy of further clinical promotion and development.
【學位授予單位】：成都中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R246.6

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