電針治療膝骨關(guān)節(jié)炎療效性的META分析
發(fā)布時間：2018-08-23 20:19
【摘要】：背景:膝關(guān)節(jié)骨性關(guān)節(jié)炎,又稱退行性膝骨關(guān)節(jié)病,增生性膝骨關(guān)節(jié)炎等,是一種多發(fā)于中老年人的慢性骨關(guān)節(jié)疾患�，F(xiàn)代醫(yī)學(xué)研究證明,膝關(guān)節(jié)的骨質(zhì)和周圍軟組織退變程度隨年齡的增長而加劇,高度的致畸和致殘率,嚴(yán)重影響患者的生活質(zhì)量。目前,臨床上治療方法有很多種,取得了一定的治療效果。但由于膝骨關(guān)節(jié)炎的病因病機(jī)仍處于不明朗的狀況,所以難以達(dá)到理想的治療效果,西醫(yī)的藥物治療又伴有不同程度的不良反應(yīng),所以尋找經(jīng)濟(jì)安全的治療方法成為了社會的關(guān)注焦點。針刺腧穴有通經(jīng)絡(luò)、補氣血、消腫止痛的功效,針刺加電針被證實可以活躍局部組織血液循環(huán)、抑制炎性物質(zhì)發(fā)展,同時提高局部組織的痛閾,從而減輕疼痛等臨床癥狀。國內(nèi)多數(shù)臨床文獻(xiàn)認(rèn)為針刺或電針對膝骨關(guān)節(jié)炎的治療療效樂觀,但國際上對此仍有諸多看法。為探討針刺及電針療法對膝骨關(guān)節(jié)炎的臨床療效,有必要對相關(guān)文獻(xiàn)進(jìn)行科學(xué)、系統(tǒng)的評價與分析,得出結(jié)論,更客觀的指導(dǎo)本病的臨床治療。目的:對電針治療膝骨關(guān)節(jié)炎的臨床療效研究這一課題的多項獨立臨床研究進(jìn)行Meta分析,希望通過探討電針治療膝骨關(guān)節(jié)炎的有效率及不良反應(yīng)發(fā)生率,可以為膝關(guān)節(jié)骨關(guān)節(jié)炎的臨床治療的研究提供循證依據(jù),并可以為臨床指導(dǎo)治療提供證據(jù)。方法:計算機(jī)檢索CBM、CNKI、萬方、維普、Pub Med和The Cochrane Library,搜集電針治療膝骨關(guān)節(jié)炎的隨機(jī)對照試驗。使用Revman 5.3軟件對數(shù)據(jù)進(jìn)行Meta分析。結(jié)果:本分析納入隨機(jī)對照試驗共13篇,實驗組均為電針治療,對照組均為西藥治療。一篇為口服扶他林緩釋片,一篇為口服美洛昔康,一篇為口服鹽酸氨基葡萄糖片,一篇為口服芬必得,兩篇為雙氯芬酸鈉,三篇為布洛芬,一篇為塞來昔布,一篇為壯骨關(guān)節(jié)丸,兩篇為口服扶他林或芬必得。Meta分析結(jié)果顯示:電針治療膝骨關(guān)節(jié)炎療效性與安全性與藥物相比,具有統(tǒng)計學(xué)意義。結(jié)論:電針治療膝骨關(guān)節(jié)炎,較藥物組治療療效顯著,且具有安全性。
[Abstract]:Background: knee osteoarthritis, also known as degenerative knee osteoarthritis, hyperplastic knee osteoarthritis, is a kind of chronic osteoarthritis in middle and old people. Modern medical research has proved that the degree of degeneration of bone and surrounding soft tissue of knee joint increases with age, and the high rate of teratogenicity and disability seriously affects the quality of life of patients. At present, there are many kinds of clinical treatment methods, and have achieved certain therapeutic effects. However, because the etiology and pathogenesis of knee osteoarthritis are still in an uncertain state, it is difficult to achieve an ideal therapeutic effect. Western medicine treatment is accompanied by varying degrees of adverse reactions. Therefore, the search for economic safety treatment has become the focus of social attention. Acupuncture acupoints have the effect of opening meridian, replenishing qi and blood, reducing swelling and relieving pain. Acupuncture plus electroacupuncture has been proved to be able to activate blood circulation of local tissues, inhibit the development of inflammatory substances, and increase the pain threshold of local tissues, thereby alleviating the clinical symptoms such as pain and so on. Most clinical literatures at home think that acupuncture or electroacupuncture is an optimistic treatment for knee osteoarthritis, but there are still many views on it internationally. In order to study the clinical effect of acupuncture and electroacupuncture on knee osteoarthritis, it is necessary to make a scientific, systematic evaluation and analysis of the relevant literature, and draw a conclusion, which is more objective to guide the clinical treatment of this disease. Objective: to study the clinical efficacy of electroacupuncture in the treatment of knee osteoarthritis by Meta analysis in order to explore the effective rate and adverse reaction rate of electroacupuncture in treating knee osteoarthritis. It can provide evidence basis for clinical treatment of knee osteoarthritis and provide evidence for clinical treatment. Methods: a randomized controlled trial was conducted to search CBM,CNKI, Wanfang, Weipub Med and The Cochrane Library, for the treatment of knee osteoarthritis by electroacupuncture. The data were analyzed by Meta using Revman 5.3 software. Results: there were 13 randomized controlled trials. The experimental group was treated with electroacupuncture and the control group with western medicine. One is oral flutamine sustained release tablets, one is oral meloxicam, one is oral glucosamine hydrochloride, one is oral Fenbid, two are diclofenac sodium, three are ibuprofen, one is celecoxib, one is oral glucosamine hydrochloride, one is oral Fenbid, two are diclofenac sodium, three are ibuprofen, one is celecoxib. One was Zhuanggujianwan and the other was oral Fu Talin or Fenbid .Meta analysis showed that the efficacy and safety of electroacupuncture in treating knee osteoarthritis were statistically significant compared with the drug. Conclusion: electroacupuncture treatment of knee osteoarthritis is more effective and safe than that of drug group.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R246.9
，
本文編號：2199814
[Abstract]:Background: knee osteoarthritis, also known as degenerative knee osteoarthritis, hyperplastic knee osteoarthritis, is a kind of chronic osteoarthritis in middle and old people. Modern medical research has proved that the degree of degeneration of bone and surrounding soft tissue of knee joint increases with age, and the high rate of teratogenicity and disability seriously affects the quality of life of patients. At present, there are many kinds of clinical treatment methods, and have achieved certain therapeutic effects. However, because the etiology and pathogenesis of knee osteoarthritis are still in an uncertain state, it is difficult to achieve an ideal therapeutic effect. Western medicine treatment is accompanied by varying degrees of adverse reactions. Therefore, the search for economic safety treatment has become the focus of social attention. Acupuncture acupoints have the effect of opening meridian, replenishing qi and blood, reducing swelling and relieving pain. Acupuncture plus electroacupuncture has been proved to be able to activate blood circulation of local tissues, inhibit the development of inflammatory substances, and increase the pain threshold of local tissues, thereby alleviating the clinical symptoms such as pain and so on. Most clinical literatures at home think that acupuncture or electroacupuncture is an optimistic treatment for knee osteoarthritis, but there are still many views on it internationally. In order to study the clinical effect of acupuncture and electroacupuncture on knee osteoarthritis, it is necessary to make a scientific, systematic evaluation and analysis of the relevant literature, and draw a conclusion, which is more objective to guide the clinical treatment of this disease. Objective: to study the clinical efficacy of electroacupuncture in the treatment of knee osteoarthritis by Meta analysis in order to explore the effective rate and adverse reaction rate of electroacupuncture in treating knee osteoarthritis. It can provide evidence basis for clinical treatment of knee osteoarthritis and provide evidence for clinical treatment. Methods: a randomized controlled trial was conducted to search CBM,CNKI, Wanfang, Weipub Med and The Cochrane Library, for the treatment of knee osteoarthritis by electroacupuncture. The data were analyzed by Meta using Revman 5.3 software. Results: there were 13 randomized controlled trials. The experimental group was treated with electroacupuncture and the control group with western medicine. One is oral flutamine sustained release tablets, one is oral meloxicam, one is oral glucosamine hydrochloride, one is oral Fenbid, two are diclofenac sodium, three are ibuprofen, one is celecoxib, one is oral glucosamine hydrochloride, one is oral Fenbid, two are diclofenac sodium, three are ibuprofen, one is celecoxib. One was Zhuanggujianwan and the other was oral Fu Talin or Fenbid .Meta analysis showed that the efficacy and safety of electroacupuncture in treating knee osteoarthritis were statistically significant compared with the drug. Conclusion: electroacupuncture treatment of knee osteoarthritis is more effective and safe than that of drug group.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R246.9
，
本文編號：2199814
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