蒙藥山沉香普通粉與超微粉氣相色譜指紋圖譜的研究
發(fā)布時間:2018-08-08 16:28
【摘要】:目的:建立蒙藥山沉香藥材氣相色譜法的特征指紋圖譜研究方法,揭示超微粉碎對山沉香揮發(fā)性成分溶出的影響。方法:采用氣相色譜分析手段對山沉香揮發(fā)性成分進(jìn)行分析,利用"中藥色譜指紋圖譜相似度評價系統(tǒng)"2004A版進(jìn)行比較分析,NIST05普庫檢索對主要指紋峰進(jìn)行歸屬。結(jié)果:建立了山沉香藥材氣相色譜指紋圖譜共用模式,10批山沉香藥材相似度分析結(jié)果為相似度均0.95;通過對普通粉與超微粉指紋圖譜的分析證明,山沉香超微粉碎后,化學(xué)成分種類數(shù)目并未發(fā)生改變,但其主要化學(xué)成分的含量明顯提高(P0.05)。結(jié)論:該分析方法簡便快速、準(zhǔn)確可靠,重現(xiàn)性好,可作為山沉香藥材的鑒定和質(zhì)量控制的有效方法。
[Abstract]:Objective: to establish a method for the study of the characteristic fingerprint of Mongolian Herba Acanthopsis by gas chromatography, and to reveal the effect of ultrafine pulverization on the dissolution of volatile components of Acanthopsis mongolicum. Methods: the volatile components were analyzed by gas chromatography, and the main fingerprint peaks were analyzed by using the similarity Evaluation system of chromatographic fingerprint of traditional Chinese Medicine (2004A). Results: the common pattern of gas chromatographic fingerprint was established. The results of similarity analysis showed that the similarity was 0.95.The fingerprint of common powder and ultrafine powder proved that after ultrafine grinding, the similarity was 0.95. The number of chemical constituents did not change, but the content of the main chemical components increased significantly (P0.05). Conclusion: this method is simple, rapid, accurate, reliable and reproducible, and can be used as an effective method for the identification and quality control of Herba Acanthopsis.
【作者單位】: 內(nèi)蒙古醫(yī)科大學(xué);
【基金】:國家科技部支撐計(jì)劃蒙藥產(chǎn)業(yè)化共性關(guān)鍵技術(shù)研究項(xiàng)目(No.2012BAI28B01)~~
【分類號】:R29;O657.71
本文編號:2172359
[Abstract]:Objective: to establish a method for the study of the characteristic fingerprint of Mongolian Herba Acanthopsis by gas chromatography, and to reveal the effect of ultrafine pulverization on the dissolution of volatile components of Acanthopsis mongolicum. Methods: the volatile components were analyzed by gas chromatography, and the main fingerprint peaks were analyzed by using the similarity Evaluation system of chromatographic fingerprint of traditional Chinese Medicine (2004A). Results: the common pattern of gas chromatographic fingerprint was established. The results of similarity analysis showed that the similarity was 0.95.The fingerprint of common powder and ultrafine powder proved that after ultrafine grinding, the similarity was 0.95. The number of chemical constituents did not change, but the content of the main chemical components increased significantly (P0.05). Conclusion: this method is simple, rapid, accurate, reliable and reproducible, and can be used as an effective method for the identification and quality control of Herba Acanthopsis.
【作者單位】: 內(nèi)蒙古醫(yī)科大學(xué);
【基金】:國家科技部支撐計(jì)劃蒙藥產(chǎn)業(yè)化共性關(guān)鍵技術(shù)研究項(xiàng)目(No.2012BAI28B01)~~
【分類號】:R29;O657.71
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