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針灸期待值對(duì)針灸治療圍絕經(jīng)期綜合征療效影響的臨床評(píng)價(jià)

發(fā)布時(shí)間:2018-08-07 08:39
【摘要】:目的:針灸期待值是指患者對(duì)自己病情發(fā)展的預(yù)見和對(duì)針刺療法的接受程度,與針灸療效存在一定的相關(guān)性。本研究以圍絕經(jīng)期綜合征患者為研究對(duì)象,觀察針灸期待值對(duì)針灸治療該病療效的影響。方法:本研究為“絕經(jīng)過渡期患者針灸干預(yù)優(yōu)效性隨機(jī)對(duì)照研究”的部分內(nèi)容,將符合納入標(biāo)準(zhǔn)的圍絕經(jīng)期綜合征患者納入試驗(yàn),共103例,按照針灸期待值的高低分為高期待值組和低期待值組。兩組均采用針刺和耳穴貼壓治療,主穴選取關(guān)元,雙側(cè)子宮,雙側(cè)足三里,雙側(cè)三陰交,每次治療30min,前4周每周治療3次,后8周每周治療2次,12周共計(jì)28次;耳穴選穴為心、肝、腎、內(nèi)分泌、神門等穴,每周2次,雙耳交替,共治療12周。針灸期待值于基線期進(jìn)行評(píng)價(jià);主要療效指標(biāo)為絕經(jīng)癥狀評(píng)分量表(MRS)、次要療效指標(biāo)包括圍絕經(jīng)期生存質(zhì)量量表(MENQOL)和平均24h烘熱積分,分別于入組時(shí)、入組第4周、第12周、第16周、第24周和第36周進(jìn)行療效指標(biāo)的評(píng)價(jià),觀察針灸期待值對(duì)療效的影響。結(jié)果:1.兩組基線均衡兩組研究對(duì)象的一般情況基線比較,其差異無統(tǒng)計(jì)學(xué)意義(P0.05),主要療效指標(biāo)MRS中的泌尿生殖癥狀維度積分、心理癥狀維度積分、軀體癥狀維度積分基線比較,差異無統(tǒng)計(jì)學(xué)意義(P≥0.05);次要指標(biāo)MENQOL的軀體癥狀維度積分、血管舒張癥狀維度積分、社會(huì)心理癥狀維度積分基線比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05),生殖內(nèi)分泌癥狀維度積分基線比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),但治療期與治療后的組間比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05),故無需進(jìn)行協(xié)方差檢驗(yàn);兩組平均24h烘熱積分基線比較的差異無統(tǒng)計(jì)學(xué)意義(P0.05)。組間均衡,兩組可進(jìn)行比較。2.組內(nèi)比較:MRS量表各維度值在第0周與第4周、第0周與第12周的差異有統(tǒng)計(jì)學(xué)意義(P0.05);第0周與第16、第24、第36周,第12周與第16、第24、第36周的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。MENQOL量表各維度值在第0周與第4周、第0周與第12周的差異有統(tǒng)計(jì)學(xué)意義(P0.05);第0周與第16、第24、第36周,第12周與第16、第24、第36周的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。平均24h烘熱積分值在第0周與第4周、第0周與第12周的差異有統(tǒng)計(jì)學(xué)意義(P0.05);第0周與第16、第24、第36周,第12周與第16、第24、第36周的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。3.組間比較:主要指標(biāo)MRS各維度積分改善值組間比較,第4周、第12周、第16周、第24周、第36周積分改善值的差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。次要指標(biāo)MENQOL的社會(huì)心理癥狀維度、血管舒張癥狀維度、生殖內(nèi)分泌癥狀維度的積分改善值在第4周、第12周、第16周、第24周、第36周組間比較,其差異均無統(tǒng)計(jì)學(xué)意義(P0.05);軀體癥狀維度積分改善值在第12周、第16周、第24周的組間比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。次要指標(biāo)平均24h烘熱積分改善值在各評(píng)價(jià)時(shí)間點(diǎn)的組間比較,其差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:1.針灸治療圍絕經(jīng)期綜合征有效,能改善其癥狀,提高患者生活質(zhì)量。2.期待值高低對(duì)圍絕經(jīng)綜合征的多數(shù)癥狀影響不明顯,但患者高期待值即積極期待者可能對(duì)圍絕經(jīng)期疼痛癥狀有更好的改善作用,高期待對(duì)針灸療效可能具有更積極的影響作用使得針灸的總療效高于低期待者。
[Abstract]:Objective: the expectant value of acupuncture and moxibustion refers to the patient's foresight of the development of his illness and the degree of acceptance of acupuncture therapy. There is a certain correlation with the effect of acupuncture and moxibustion. In this study, the effect of acupuncture expectant value on the treatment of the disease was observed with perimenopausal syndrome. A total of 103 cases of perimenopausal syndrome were divided into high expectant and low expectant groups according to the expectations of acupuncture and moxibustion. The two groups were treated with acupuncture and auricular point sticking, the main points were selected, bilateral uterus, bilateral Zusanli, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, bilateral, and bilateral. The treatment of 30min, 3 times a week for the first 4 weeks, 2 times a week for the first 8 weeks and 28 times for 12 weeks, the auricular point selection was the heart, the liver, the kidney, the endocrine, the Shen men and other points, 2 times a week, and the double ears were alternately treated for 12 weeks. The value of acupuncture and moxibustion was evaluated at the baseline period; the main therapeutic index was the menopause symptom score scale (MRS) and secondary therapeutic target package. In the group of fourth weeks, Twelfth weeks, sixteenth weeks, sixteenth weeks, twenty-fourth and thirty-sixth weeks, the effect of acupuncture expectancy on the curative effect was evaluated. The results were: the general baseline comparison between the 1. two groups of baseline equilibrium two groups was not statistically different. P0.05, the dimension integral of genitourinary symptoms in MRS, the dimension integral of psychological symptoms, and the comparison of the dimension integral baseline of somatic symptoms were not statistically significant (P > 0.05); the somatic symptom dimension integral of secondary index MENQOL, the integral of vasodilatation, the comparison of the dimension integral baseline of social psychological symptoms, and the difference between them, were poor. There was no statistical significance (P0.05). There was significant difference in the dimension integral baseline of reproductive endocrine symptoms (P0.05), but there was no significant difference between the treatment period and the group after treatment (P0.05), so there was no need for covariance test; there was no statistical difference between the two groups (P0.05). The comparison between the two groups could be compared in the.2. group: the values of each dimension of the MRS scale were zeroth and fourth weeks, and the difference between the zeroth and the twelfth weeks was statistically significant (P0.05); the zeroth weeks and sixteenth, twenty-fourth, thirty-sixth weeks, Twelfth weeks and sixteenth, twenty-fourth, and thirty-sixth weeks were statistically significant (P0.05) the dimensions of the.MENQOL scales were in the weeks and weeks, and the weeks and weeks. The difference was statistically significant (P0.05). The difference between zeroth weeks and sixteenth, twenty-fourth, thirty-sixth weeks, Twelfth weeks and sixteenth, twenty-fourth, thirty-sixth weeks was statistically significant (P0.05). The average 24h heating integral value was between zeroth and fourth weeks, while zeroth weeks and twelfth weeks were statistically significant. The difference was statistically significant (P0.05).3. group comparison: the main indexes of the MRS dimensions were compared between fourth weeks, Twelfth weeks, sixteenth weeks, twenty-fourth weeks, and thirty-sixth weeks, and there was no statistical significance (P0.05). The degree of social psychological symptoms, the dimension of vasodilatation, the product dimension of reproductive endocrinology, the secondary index of MENQOL. The difference was not statistically significant (P0.05) between the fourth weeks, Twelfth weeks, sixteenth weeks, twenty-fourth weeks and thirty-sixth weeks. The improvement value of physical symptom dimension integral was statistically significant in twelfth, sixteenth, and twenty-fourth weeks (P0.05). The improvement value of the average 24h heating integral was compared between the two groups at the time points of each evaluation. The difference was not statistically significant (P0.05). Conclusion: 1. the treatment of perimenopausal syndrome by Acupuncture and moxibustion is effective, can improve the symptoms and improve the quality of life of the patients with.2. expectancy on most of the symptoms of perimenopause syndrome, but the patient's high expectation, the positive expectant, may have a better effect on the symptoms of perimenopausal pain. High expectations may have a more positive effect on acupuncture efficacy, so that the total curative effect of acupuncture is higher than that of low expectations.
【學(xué)位授予單位】:成都中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2016
【分類號(hào)】:R246.3

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