【摘要】：目的:運用測評量表對單純中醫(yī)藥治療階段的淋巴瘤患者癥狀進行研究,探索其癥狀特征及中醫(yī)證型特點。方法:采用腫瘤常見癥狀及Anderson中醫(yī)癥狀調(diào)查量表(MDASI-TCM)進行問卷調(diào)查;中醫(yī)證型診斷標準參照《惡性腫瘤中醫(yī)診療指南》中淋巴瘤一章中醫(yī)辨證分型部分。對40例處于單純中醫(yī)藥治療階段的淋巴瘤患者進行橫斷面調(diào)查,調(diào)查結(jié)果運用SPSS 20.0軟件對數(shù)據(jù)進行統(tǒng)計分析,多組獨立樣本秩和檢驗分析比較不同證類對生活的干擾程度。結(jié)果:淋巴瘤患者普遍存在多種癥狀,其中發(fā)生頻率最顯著的3個癥狀為口干(65.00%)、疲勞(62.50%)、睡眠不安(62.50%),癥狀強度最顯著的3個癥狀分別是疲勞(3.10±2.99)、出汗(2.80±2.98)、口干(2.30±2.58);淋巴瘤患者辨證常出現(xiàn)兩證(37.5%)或三證(25.0%)相兼的情況;在證型頻次中,虛實夾雜證出現(xiàn)最多,占45.0%,其次為虛證,占42.5%,實證較少,僅占12.5%;虛實夾雜證類患者對一般活動、情緒、生活樂趣方面影響程度大于單純實證類及虛證類。結(jié)論:淋巴瘤患者的癥狀及證型特點較為復(fù)雜,臨床大夫在根據(jù)患者當(dāng)前癥狀表現(xiàn)進行辨證用藥的同時,可參照淋巴瘤不同分期、病理類型及ECOG下不同癥狀的發(fā)生情況,為患者進行預(yù)防性用藥或康復(fù)指導(dǎo)。
[Abstract]:Objective: to study the symptoms of lymphoma patients treated with traditional Chinese medicine (TCM) and to explore the characteristics of symptoms and syndromes. Methods: the common symptoms of tumor and Anderson Chinese Medicine symptom Survey scale (MDASI-TCM) were used to investigate the symptoms, and the diagnosis criteria of TCM syndromes referred to the part of TCM syndrome differentiation and classification in the chapter of Chinese Medicine Syndrome differentiation and Classification of Lymphoma in the Guide of diagnosis and treatment of malignant tumor. A cross-sectional investigation was carried out in 40 cases of lymphoma patients in the stage of treatment with traditional Chinese medicine. The results were statistically analyzed by SPSS 20.0 software, and the degree of interference of different syndromes to life was compared by rank sum test of multiple independent samples. Results: there are many symptoms in patients with lymphoma. The three most frequent symptoms were dry mouth (65.00%), fatigue (62.50%), restlessness of sleep (62.50%), fatigue (3.10 鹵2.99), sweating (2.80 鹵2.98), dry mouth (2.30 鹵2.58). In the frequency of syndromes, deficiency and solid inclusion syndrome appeared most, accounting for 45.0, followed by deficiency syndrome, accounting for 42.5, empirical less, only 12.5; the influence degree on general activity, emotion and life fun of patients with deficiency and solid inclusion syndrome was greater than that of pure empirical syndrome and deficiency syndrome. Conclusion: the characteristics of symptoms and syndromes in patients with lymphoma are more complicated. According to the current symptoms of the patients, the clinicians can refer to the different stages, pathological types and the occurrence of different symptoms under ECOG. Give preventive medication or rehabilitation guidance to patients.
【作者單位】： 中國中醫(yī)科學(xué)院廣安門醫(yī)院腫瘤科;
【基金】：中醫(yī)藥行業(yè)科研專項(No.201307006) 國家國際科技合作專項(No.2013DFA325)~~
【分類號】：R273

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