基于中醫(yī)傳承輔助系統(tǒng)治療慢性糜爛性胃炎的用藥規(guī)律分析
發(fā)布時(shí)間：2018-08-05 14:44
【摘要】：第一部分基于中醫(yī)傳承輔助系統(tǒng)當(dāng)代醫(yī)家治療慢性糜爛性胃炎用藥規(guī)律分析目的:基于中醫(yī)傳承輔助系統(tǒng)(V2.5)軟件,探討當(dāng)代醫(yī)家治療慢性糜爛性胃炎的中醫(yī)臨床用藥規(guī)律,以期更好的指導(dǎo)臨床遣方用藥,為進(jìn)一步研制新藥奠定基礎(chǔ)。方法:基于中醫(yī)傳承輔助系統(tǒng)(V2.5)軟件對(duì)2007-2016年公開發(fā)表在中國(guó)學(xué)術(shù)文獻(xiàn)總庫(kù)(CNKI)、維普、萬(wàn)方中文期刊數(shù)據(jù)庫(kù)的治療慢性糜爛性胃炎的中醫(yī)處方進(jìn)行數(shù)據(jù)挖掘,探討當(dāng)代醫(yī)家治療慢性糜爛性胃炎的組方用藥特點(diǎn)及配伍應(yīng)用規(guī)律。結(jié)果:通過對(duì)篩選出來的439首處方進(jìn)行分析,結(jié)果顯示,共使用219味中藥,前5味高頻次使用中藥依次為:甘草、黃連、半夏、白術(shù)、白及;藥物四氣統(tǒng)計(jì)顯示,以寒性和溫性藥物使用最多;藥物五味統(tǒng)計(jì)顯示,苦味藥使用最多;藥物歸經(jīng)分析顯示出現(xiàn)頻率較高的為脾、胃、肺經(jīng);選擇合適的支持度個(gè)數(shù)(40)及置信度(0.9),利用關(guān)聯(lián)規(guī)則分析,可導(dǎo)出7條用藥規(guī)則;利用熵層次聚類法提煉組合出治療新處方共13首。結(jié)論:1當(dāng)代醫(yī)家治療慢性糜爛性胃炎多以健脾祛濕為主,寒溫并用,攻補(bǔ)兼施,注重使用脾、胃、肺經(jīng)中的藥物,用藥廣泛。2利用中醫(yī)傳承輔助系統(tǒng)(V2.5)軟件完成了對(duì)處方的錄入、管理及分析,對(duì)于研究中藥組方規(guī)律、發(fā)現(xiàn)新處方有重要意義,對(duì)臨床治療慢性糜爛性胃炎具有一定的指導(dǎo)作用。第二部分基于中醫(yī)傳承輔助系統(tǒng)王彥剛教授治療慢性糜爛性胃炎用藥規(guī)律分析目的:基于中醫(yī)傳承輔助系統(tǒng)(V2.5)軟件,探討王彥剛教授治療慢性糜爛性胃炎的中醫(yī)臨床用藥規(guī)律,為中醫(yī)藥治療慢性糜爛性胃炎提供一個(gè)客觀的、系統(tǒng)的統(tǒng)計(jì)歸類及分析計(jì)算方法,為臨床治療慢性糜爛性胃炎提供新思路及參考。方法:基于中醫(yī)傳承輔助系統(tǒng)(V2.5)軟件對(duì)2013-2016年王彥剛教授在河北省中醫(yī)院門診治療慢性糜爛性胃炎患者的首診中醫(yī)處方進(jìn)行數(shù)據(jù)挖掘,探討王彥剛教授治療慢性糜爛性胃炎用藥規(guī)律及經(jīng)驗(yàn),最后挖掘新處方。結(jié)果:通過對(duì)508例患者的基本情況及首診處方進(jìn)行分析,結(jié)果顯示,508例患者中,男性247例,女性261例;年齡在51-60歲的人數(shù)最多;共使用220味中藥,前5味高頻次使用中藥依次為:黃芩、半夏、黃連、竹茹、茵陳;藥物四氣統(tǒng)計(jì)顯示,以寒性和溫性藥物使用最多;藥物五味統(tǒng)計(jì)顯示,苦味藥使用最多;藥物歸經(jīng)顯示出現(xiàn)頻率較高的為胃、脾、肝經(jīng);中醫(yī)證型分類統(tǒng)計(jì)顯示,濁毒內(nèi)蘊(yùn)證最多,其次為脾胃濕熱證;將220味中藥按功效分類,共使用18類中藥,前5位使用藥味數(shù)由高到低分別為清熱藥、補(bǔ)虛藥、活血化瘀藥、利水滲濕藥、理氣藥;選擇合適的支持度個(gè)數(shù)(400)及置信度(0.9),利用關(guān)聯(lián)規(guī)則分析,可導(dǎo)出15條用藥規(guī)則;利用熵層次聚類法提煉組合出治療新處方共18首。結(jié)論:1王彥剛教授認(rèn)為濁毒內(nèi)蘊(yùn)為慢性糜爛性胃炎的主要病機(jī),用藥多以化濁解毒為主,形成了通滯、化積、祛濕、滌痰、散瘀、解毒于“六位一體”的綜合性治療網(wǎng)絡(luò),強(qiáng)調(diào)治胃勿忘肝,用藥集中。2利用中醫(yī)傳承輔助平臺(tái)(V2.5)軟件完成了對(duì)處方的錄入、管理及分析,對(duì)于研究中藥組方規(guī)律、發(fā)現(xiàn)新處方及輔助傳承名老中醫(yī)經(jīng)驗(yàn)提供了有力工具,對(duì)臨床治療慢性糜爛性胃炎亦具有一定的指導(dǎo)意義。
[Abstract]:The first part is based on the traditional Chinese Medicine Inheritance assistance system for the treatment of chronic erosive gastritis by contemporary doctors. Based on the V2.5 software, this paper discusses the law of traditional Chinese medicine in the treatment of chronic erosive gastritis by modern doctors, in order to better guide the clinical medicine and lay the foundation for the further development of new drugs. Methods: Based on the traditional Chinese Medicine Inheritance assistance system (V2.5) software, data mining was published in the Chinese medical literature general library (CNKI), VP, Wanfang Chinese Journal Database for the treatment of chronic erosive gastritis in 2007-2016 years, and discussed the characteristics and compatibility rules of the prescriptions for the treatment of chronic erosive gastritis by contemporary doctors. Fruit: through the analysis of the 439 selected prescriptions, the results showed that 219 traditional Chinese medicines were used in total. The first 5 flavors of high frequency traditional Chinese medicine were as follows: Glycyrrhiza, Rhizoma Coptis, Pinellia ternata, Atractylodes macrocephala, and Rhizoma Bletillae; drug four Qi statistics showed that the use of cold and warm drugs was the most; drug five statistics showed that bitter drugs were the most used; drug meridian analysis showed analysis. High frequency is the spleen, stomach, lung meridian; select the appropriate number of support (40) and confidence (0.9), the use of association rules analysis, can derive 7 Rules of drug use, using entropy hierarchical clustering method to extract a total of 13 new prescriptions. Conclusion: 1 modern medical treatment of chronic erosive gastritis mainly to strengthen the spleen and dampness, cold temperature and use, attack and complement both application Pay attention to use the medicine in the spleen, stomach and lung meridian, and use the medicine widely.2 to use the traditional Chinese Medicine Inheritance auxiliary system (V2.5) software to complete the entry, management and analysis of the prescription. It is of great significance for the study of the law of the prescription of traditional Chinese Medicine and the discovery of the new prescription. The second part is based on the inheritance of traditional Chinese medicine. Prof. Wang Yangang in the treatment of chronic erosive gastritis by Professor Wang Yangang: Based on the software of traditional Chinese Medicine Inheritance assistant system (V2.5), the law of Professor Wang Yangang in the treatment of chronic erosive gastritis was discussed, and an objective, systematic statistical classification and analysis method were provided for the treatment of chronic erosive gastritis by traditional Chinese medicine. To provide new ideas and reference for clinical treatment of chronic erosive gastritis. Methods: Based on the software of traditional Chinese medicine V2.5 (V2.5), data mining on the first doctor's prescription of Professor Wang Yangang in the treatment of chronic erosive gastritis in the outpatient clinic of Hebei province was carried out, and the prescriptions of Professor Wang Yangang on the treatment of chronic erosive gastritis were discussed. Results: through the analysis of the basic situation and the first prescription of the 508 cases, the results showed that among the 508 patients, 247 cases were male, 261 cases were female, and the number of people aged 51-60 years was the most. A total of 220 traditional Chinese medicines were used, and the first 5 high-frequency times made traditional Chinese medicine in order of the traditional Chinese medicine: Scutellaria baicalensis, Pinellia ternata, Rhizoma Coptidis, bamboo, Yin Chen, medicine four. Gas statistics show that the use of cold and warm drugs is the most; the five statistics of drugs show that the bitter medicine is the most used; the drug return to meridian shows the high frequency of the stomach, spleen, liver meridian; TCM syndrome classification statistics show that the syndrome is the most, followed by the spleen and stomach damp heat syndrome, the 220 Chinese herbs are classified according to the efficacy, the total use of 18 kinds of traditional Chinese medicine, the first 5 make the The drug flavour was from high to low, respectively as the antipyretic medicine, supplementing the deficiency medicine, promoting blood circulation and removing stasis medicine, leudiation and humidifying medicine and physical Qi medicine; choosing the appropriate number of support (400) and confidence (0.9), using the association rules analysis, the 15 rules of drug use can be derived, and a total of 18 new prescriptions were extracted and combined by entropy hierarchical clustering method. Conclusion: 1 professor Wang Yangang believed turbid poison. It is the main pathogenesis of chronic erosive gastritis. The drug is mainly treated with turbid and detoxification. It forms the comprehensive treatment network of "six in one" with stagnation, accumulation, dispelling dampness, removing phlegm, dispersing stasis and detoxifying the "six in one", and concentrating on the administration and analysis of the prescription by using the traditional Chinese medicine V2.5 software. In the study of the rules of the prescription of Chinese medicine, we found the new prescription and the help to inherit the experience of the old Chinese medicine. It also has a certain guiding significance for the clinical treatment of chronic erosive gastritis.
【學(xué)位授予單位】：河北醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259
本文編號(hào)：2166109
[Abstract]:The first part is based on the traditional Chinese Medicine Inheritance assistance system for the treatment of chronic erosive gastritis by contemporary doctors. Based on the V2.5 software, this paper discusses the law of traditional Chinese medicine in the treatment of chronic erosive gastritis by modern doctors, in order to better guide the clinical medicine and lay the foundation for the further development of new drugs. Methods: Based on the traditional Chinese Medicine Inheritance assistance system (V2.5) software, data mining was published in the Chinese medical literature general library (CNKI), VP, Wanfang Chinese Journal Database for the treatment of chronic erosive gastritis in 2007-2016 years, and discussed the characteristics and compatibility rules of the prescriptions for the treatment of chronic erosive gastritis by contemporary doctors. Fruit: through the analysis of the 439 selected prescriptions, the results showed that 219 traditional Chinese medicines were used in total. The first 5 flavors of high frequency traditional Chinese medicine were as follows: Glycyrrhiza, Rhizoma Coptis, Pinellia ternata, Atractylodes macrocephala, and Rhizoma Bletillae; drug four Qi statistics showed that the use of cold and warm drugs was the most; drug five statistics showed that bitter drugs were the most used; drug meridian analysis showed analysis. High frequency is the spleen, stomach, lung meridian; select the appropriate number of support (40) and confidence (0.9), the use of association rules analysis, can derive 7 Rules of drug use, using entropy hierarchical clustering method to extract a total of 13 new prescriptions. Conclusion: 1 modern medical treatment of chronic erosive gastritis mainly to strengthen the spleen and dampness, cold temperature and use, attack and complement both application Pay attention to use the medicine in the spleen, stomach and lung meridian, and use the medicine widely.2 to use the traditional Chinese Medicine Inheritance auxiliary system (V2.5) software to complete the entry, management and analysis of the prescription. It is of great significance for the study of the law of the prescription of traditional Chinese Medicine and the discovery of the new prescription. The second part is based on the inheritance of traditional Chinese medicine. Prof. Wang Yangang in the treatment of chronic erosive gastritis by Professor Wang Yangang: Based on the software of traditional Chinese Medicine Inheritance assistant system (V2.5), the law of Professor Wang Yangang in the treatment of chronic erosive gastritis was discussed, and an objective, systematic statistical classification and analysis method were provided for the treatment of chronic erosive gastritis by traditional Chinese medicine. To provide new ideas and reference for clinical treatment of chronic erosive gastritis. Methods: Based on the software of traditional Chinese medicine V2.5 (V2.5), data mining on the first doctor's prescription of Professor Wang Yangang in the treatment of chronic erosive gastritis in the outpatient clinic of Hebei province was carried out, and the prescriptions of Professor Wang Yangang on the treatment of chronic erosive gastritis were discussed. Results: through the analysis of the basic situation and the first prescription of the 508 cases, the results showed that among the 508 patients, 247 cases were male, 261 cases were female, and the number of people aged 51-60 years was the most. A total of 220 traditional Chinese medicines were used, and the first 5 high-frequency times made traditional Chinese medicine in order of the traditional Chinese medicine: Scutellaria baicalensis, Pinellia ternata, Rhizoma Coptidis, bamboo, Yin Chen, medicine four. Gas statistics show that the use of cold and warm drugs is the most; the five statistics of drugs show that the bitter medicine is the most used; the drug return to meridian shows the high frequency of the stomach, spleen, liver meridian; TCM syndrome classification statistics show that the syndrome is the most, followed by the spleen and stomach damp heat syndrome, the 220 Chinese herbs are classified according to the efficacy, the total use of 18 kinds of traditional Chinese medicine, the first 5 make the The drug flavour was from high to low, respectively as the antipyretic medicine, supplementing the deficiency medicine, promoting blood circulation and removing stasis medicine, leudiation and humidifying medicine and physical Qi medicine; choosing the appropriate number of support (400) and confidence (0.9), using the association rules analysis, the 15 rules of drug use can be derived, and a total of 18 new prescriptions were extracted and combined by entropy hierarchical clustering method. Conclusion: 1 professor Wang Yangang believed turbid poison. It is the main pathogenesis of chronic erosive gastritis. The drug is mainly treated with turbid and detoxification. It forms the comprehensive treatment network of "six in one" with stagnation, accumulation, dispelling dampness, removing phlegm, dispersing stasis and detoxifying the "six in one", and concentrating on the administration and analysis of the prescription by using the traditional Chinese medicine V2.5 software. In the study of the rules of the prescription of Chinese medicine, we found the new prescription and the help to inherit the experience of the old Chinese medicine. It also has a certain guiding significance for the clinical treatment of chronic erosive gastritis.
【學(xué)位授予單位】：河北醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259
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