本文選題：河車路 + 長盒灸法　； 參考：《成都中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：采用四川省中醫(yī)院著名中醫(yī)大家李仲愚先生的河車路理論,結(jié)合長盒灸法,以河車路(大椎至長強之間)長盒灸法為治療方案治療脆性糖尿病后抑郁癥脾腎陽虛型,比較其與口服百憂解(鹽酸氟西汀膠囊)臨床治療的療效差異,篩選治療脆性糖尿病后抑郁癥的優(yōu)勢方案,為推廣溫陽灸法、河車路理論的臨床運用提供客觀試驗依據(jù)。方法：把符合納入標(biāo)準(zhǔn)的65例脆性糖尿病脾腎陽虛型抑郁癥受試者隨機分為試驗組與對照組,經(jīng)排除本次臨床研究過程中脫落、剔除的病例后,治療組最終完成31例,對照組最終完成30例。試驗組采取河車路長盒灸法,每日1次,10次為1療程,共計2個療程。對照組采用口服百憂解,每日40mg,連續(xù)服用20天。觀察兩組治療前、后漢密爾頓抑郁量表(HAMD)、抑郁自評量表(SDS)、中醫(yī)證候量表的指標(biāo)變化,比較兩組之間的差異。結(jié)果：(1)基線比較：治療前兩組脆性糖尿病后抑郁癥脾腎陽虛型受試者在年齡、性別、脆性糖尿病病程、抑郁癥病程、中醫(yī)證候量表評分、HAMD-17項評分、SDS評分比較,組間均衡(P0.05),具有可比性。(2)組間比較：治療后兩組脆性糖尿病后抑郁癥脾腎陽虛型患者HAMD-17項評分、SDS評分組間對比,差異無統(tǒng)計學(xué)意義(P0.05)；治療后兩組中醫(yī)證候量表評分組間對比,差異有統(tǒng)計學(xué)意義(P0.05)。(3)組內(nèi)比較：治療前、后兩組脆性糖尿病后抑郁癥脾腎陽虛型患者HAMD-17項評分、SDS評分、中醫(yī)證候量表評分組內(nèi)對比,差異均具有統(tǒng)計學(xué)意義(P0.05)。(4)總體療效比較：治療后根據(jù)療效判定準(zhǔn)則判定,治療組共31人,痊愈0人,顯效19人,有效8人,無效4人,總有效率86.70%；對照組30人,痊愈0人,顯效14人,有效8人,無效8人,總效率73.21%,兩組患者總有效率進行比較,差異無統(tǒng)計學(xué)意義(P0.05)。結(jié)論：(1)河車路長盒灸法在改善脆性糖尿病后抑郁癥脾腎陽虛型患者中醫(yī)臨床癥狀上療效較對照組更優(yōu),但HAMD-17項評分、SDS評分變化與對照組比較無明顯差異。(2)河車路長盒灸法操作簡便,安全有效,無毒副反應(yīng),值得臨床推廣運用。
[Abstract]:Objective: to adopt Mr. Li Zhongyu's theory of river car road of Sichuan traditional Chinese Medicine Hospital and combine long box moxibustion with long box moxibustion to treat the deficiency of spleen and kidney yang in depressive patients with brittle diabetes mellitus by using long box moxibustion between Dazhui and Changqiang. To compare the curative effect between Prozac hydrochloride and oral fluoxetine hydrochloride, to screen the superior scheme for treating depression after brittle diabetes, to provide the objective experimental basis for popularizing the moxibustion method of warming yang and the clinical application of the theory of river car road. Methods: 65 subjects of depressive patients with fragile diabetes mellitus with spleen and kidney yang deficiency were randomly divided into two groups: the experimental group and the control group. 31 cases in the treatment group were excluded from the clinical study and eliminated. In the control group, 30 cases were finally completed. The experimental group was treated with long box moxibustion, 10 times a day as a course of treatment, a total of 2 courses. The control group was treated with Prozac 40 mg daily for 20 days. The indexes of Hamilton Depression scale (Hamd), Self-rating Depression scale (SDS) and TCM Syndrome scale (TCM) were observed before and after treatment, and the differences between the two groups were compared. Results: (1) baseline comparison: before treatment, two groups of subjects of depression with deficiency of spleen and kidney yang were compared in age, sex, course of brittle diabetes, course of depression, score of TCM syndromes scale and SDS score. (2) comparison between the two groups: after treatment, there was no significant difference in HAMD-17 score and SDS score between the two groups of depression patients with spleen and kidney yang deficiency after treatment (P0.05); after treatment, the scores of TCM syndrome scale were compared between the two groups. The difference was statistically significant (P0.05). (3): before and after treatment, the scores of HAMD-17 items in depression patients with deficiency of spleen and kidney yang, and the scores of TCM syndromes were compared before and after treatment. The difference was statistically significant (P0.05). (4). According to the criteria of curative effect, there were 31 patients in the treatment group, 0 were cured, 19 were effective, 8 were effective, 4 were ineffective, the total effective rate was 86.70, while in the control group, 30 patients were cured. The total efficiency of the two groups was 73.21. There was no significant difference in the total effective rate between the two groups (P0.05). Conclusion: (1) the effect of long box moxibustion on improving the clinical symptoms of patients with spleen and kidney yang deficiency after brittle diabetes mellitus is better than that of the control group. But there was no significant difference in SDS score between HAMD-17 score and control group. (2) the long box moxibustion method on Heche Road was simple, safe and effective, and had no toxicity and side effects, so it was worth popularizing in clinic.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R246.1

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本文編號：2098513