本文選題：調(diào)脂湯 + 痰瘀阻絡(luò)型　； 參考：《南京中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:觀察調(diào)脂湯治療痰瘀阻絡(luò)型冠心病心絞痛合并血脂異�；颊叩寞熜Ъ鞍踩�,為臨床提供新的思路和方法。方法:選取2016年4月至2017年1月在徐州市中醫(yī)院就診的痰瘀阻絡(luò)型冠心病合并血脂異常的住院患者60例。將患者按隨機表法分組,分為對照組31例,采用常規(guī)西醫(yī)方案:阿司匹林腸溶片、琥珀酸美托洛爾緩釋片、單硝酸異山梨酯片、阿托伐他汀鈣等治療;治療組29例,在對照組基礎(chǔ)上加服自擬調(diào)脂湯。兩組共服藥30天,觀察結(jié)束后,比較兩組治療前后相關(guān)血脂指標(biāo)、超敏C反應(yīng)蛋白、中醫(yī)證候積分和安全性指標(biāo)的改變。運用SPSS 19.0統(tǒng)計軟件進(jìn)行結(jié)果分析。結(jié)果:治療后兩組相關(guān)血脂指標(biāo)均降低,治療組與對照組相比較,血脂指標(biāo)降低更為明顯,差異有統(tǒng)計學(xué)意義(P0.05),且治療組總有效率高于對照組,亦存在統(tǒng)計學(xué)差異(P0.05);兩組均能降低超敏C反應(yīng)蛋白水平,但兩組療效差異無統(tǒng)計學(xué)意義(P0.05);兩組中醫(yī)癥候積分較前均有所改善,且治療組優(yōu)于對照組,差異有統(tǒng)計學(xué)意義(P0.05);兩組治療前后安全性指標(biāo)無明顯改變,兩組對比差異無統(tǒng)計學(xué)意義(P0.05)。結(jié)論:調(diào)脂湯聯(lián)合西藥可以改善痰瘀阻絡(luò)型冠心病心絞痛合并血脂異�；颊叩呐R床癥狀,顯著降低血脂,安全性較好,適合臨床推廣。
[Abstract]:Objective: to observe the efficacy and safety of Tiaozhi decoction in the treatment of angina pectoris complicated with dyslipidemia in patients with phlegm and stagnation of collaterals. Methods: from April 2016 to January 2017, 60 cases of coronary heart disease complicated with dyslipidemia of phlegm and blood stasis were selected from Xuzhou Hospital of traditional Chinese Medicine. The patients were randomly divided into control group (n = 31) and control group (n = 31) treated with aspirin enteric-coated tablets, metoprolol succinate sustained-release tablets, isosorbide mononitrate tablets, Atto vastatin calcium, etc. In the control group on the basis of the addition of self-made Tiaozhi decoction. The changes of blood lipid index, hypersensitive C-reactive protein, TCM syndromes score and safety index were compared before and after treatment. The results were analyzed by SPSS 19.0 software. Results: compared with the control group, the blood lipid index of the treatment group was lower than that of the control group, the difference was statistically significant (P 0.05), and the total effective rate of the treatment group was higher than that of the control group. There was also a statistical difference between the two groups (P 0.05). Both groups could reduce the level of hypersensitive C-reactive protein, but there was no significant difference in curative effect between the two groups (P 0.05). The scores of TCM symptoms in the two groups were improved compared with the former, and the treatment group was better than the control group. The difference was statistically significant (P 0.05), and there was no significant change in the safety index before and after treatment between the two groups, but there was no significant difference between the two groups (P 0.05). Conclusion: Tiaozhi decoction combined with western medicine can improve the clinical symptoms of angina pectoris complicated with dyslipidemia in patients with phlegm and stasis obstruction angina pectoris and dyslipidemia. It is safe and suitable for clinical application.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R259

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